Research ExplorerResearch UnitsDepartment of Stem Cell Transplantation Publications

Department of Stem Cell Transplantation

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Publications

  1. 2003

  2. Predictable and efficient retroviral gene transfer into murine bone marrow repopulating cells using a defined vector dose

    Li, Z., Schwieger, M., Lange, C., Kraunus, J., Sun, H., van den Akker, E., Modlich, U., Serinsöz, E., Will, E., von Laer, D., Stocking, C., Fehse, B., Schiedlmeier, B. & Baum, C., 01.12.2003, In: Experimental hematology. 31, 12, p. 1206-14 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. Mutagenesis by retroviral transgene insertion: risk assessment and potential alternatives

    Baum, C. & Fehse, B., 10.2003, In: Current opinion in molecular therapeutics. 5, 5, p. 458-62 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  4. Minor histocompatibility antigens on canine hemopoietic progenitor cells

    Weber, M., Lange, C., Günther, W., Franz, M., Kremmer, E. & Kolb, H-J., 15.06.2003, In: J IMMUNOL. 170, 12, p. 5861-8 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Receptor activator of nuclear factor kappaB ligand plays a nonredundant role in doxorubicin-induced apoptosis

    Müller, I., Pfister, S. M., Grohs, U., Zweigner, J., Handgretinger, R., Niethammer, D. & Bruchelt, G., 15.04.2003, In: CANCER RES. 63, 8, p. 1772-5 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Side effects of retroviral gene transfer into hematopoietic stem cells

    Baum, C., Düllmann, J., Li, Z., Fehse, B., Meyer, J., Williams, D. A. & von Kalle, C., 15.03.2003, In: BLOOD. 101, 6, p. 2099-114 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Review article › Research

  7. ATG as part of the conditioning regimen reduces transplant-related mortality (TRM) and improves overall survival after unrelated stem cell transplantation in patients with chronic myelogenous leukemia (CML).

    Zander, A. R., Kröger, N., Schleuning, M., Finke, J., Zabelina, T., Beelen, D., Schwerdtfeger, R., Baurmann, H., Bornhäuser, M., Ehninger, G., Fauser, A. A., Kiehl, M., Trenschel, R., Ottinger, H. D., Bertz, H., Berger, J., Kolb, H-J. & Schaefer, U. W., 2003, In: BONE MARROW TRANSPL. 32, 4, p. 355-361 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. Characterization of cell types during rat liver development.

    Fiegel, H. C., Park, J. J. H., Lioznov, M., Martin, A., Jaeschke-Melli, S., Kaufmann, P. M., Fehse, B., Zander, A. R. & Kluth, D., 2003, In: HEPATOLOGY. 37, 1, p. 148-154 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  9. Hepatic lineages isolated from developing rat liver show different ways of maturation.

    Fiegel, H. C., Kluth, J., Lioznov, M., Holzhüter, S., Fehse, B., Zander, A. & Kluth, D., 2003, In: BIOCHEM BIOPH RES CO. 305, 1, p. 46-53 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Influence of anti-thymocyte globulin as part of the conditioning regimen on immune reconstitution following matched related bone marrow transplantation.

    Fehse, N., Fehse, B., Kröger, N-M., Zabelina, T., Freiberger, P., Krüger, W., Kabisch, H., Erttmann, R. & Zander, A., 2003, In: J HEMATOTH STEM CELL. 12, 2, p. 237-242 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Liver-specific gene expression in cultured human hematopoietic stem cells.

    Fiegel, H. C., Lioznov, M., Cortes-Dericks, L., Lange, C., Kluth, D., Fehse, B. & Zander, A. R., 2003, In: STEM CELLS. 21, 1, p. 98-104 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Myeloablative intensified conditioning regimen with in vivo T-cell depletion (ATG) followed by allografting in patients with advanced multiple myeloma. A phase I/II study of the German Study-group Multiple Myeloma (DSMM).

    Kröger, N-M., Einsele, H., Wolff, D., Casper, J., Freund, M., Derigs, G., Wandt, H., Schäfer-Eckart, K., Wittkowsky, G., Schmitz, N., Krüger, W., Zabelina, T., Renges, H., Ayuketang Ayuk, F., Krüll, A. & Zander, A., 2003, In: BONE MARROW TRANSPL. 31, 11, p. 973-979 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Non-overt disseminated intravascular coagulation in patients during treatment with antithymocyte globulin for unrelated allogeneic hematopoietic stem cell transplantation.

    Weber, M., Kröger, N., Langer, F., Hansen, A., Zabelina, T., Eifrig, B., Hossfeld, D. K. & Zander, A. R., 2003, In: BONE MARROW TRANSPL. 31, 9, p. 817-822 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. 2002

  15. A novel 'sort-suicide' fusion gene vector for T cell manipulation

    Fehse, B., Kustikova, O. S., Li, Z., Wahlers, A., Bohn, W., Beyer, W. R., Chalmers, D., Tiberghien, P., Kühlcke, K., Zander, A. R. & Baum, C., 12.2002, In: GENE THER. 9, 23, p. 1633-1638 6 p.

    Research output: SCORING: Contribution to journal › Short publication › Research › peer-review

  16. Human mesenchymal stem cells are not of donor origin in patients with severe aplastic anemia who underwent sex-mismatched allogeneic bone marrow transplant

    Stute, N., Fehse, B., Schröder, J., Arps, S., Adamietz, P., Held, K. R. & Zander, A. R., 12.2002, In: J HEMATOTH STEM CELL. 11, 6, p. 977-984 8 p.

    Research output: SCORING: Contribution to journal › Short publication › Research › peer-review

  17. Molecular methods for detection and quantification of myeloma cells after bone marrow transplantation: comparison between real-time quantitative and nested PCR

    Tögel, F., Kröger, N., Korioth, F., Fehse, B. & Zander, A. R., 12.2002, In: J HEMATOTH STEM CELL. 11, 6, p. 971-976 6 p.

    Research output: SCORING: Contribution to journal › Short publication › Research › peer-review

  18. Interleukin-10 modulation of alloreactivity and graft-versus-host reactions

    Wang, X-N., Lange, C., Schulz, U., Sviland, L., Eissner, G., Oliver, K. M., Jackson, G. H., Holler, E. & Dickinson, A. M., 27.09.2002, In: TRANSPLANTATION. 74, 6, p. 772-8 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Persisting multilineage transgene expression in the clonal progeny of a hematopoietic stem cell

    Li, Z., Fehse, B., Schiedlmeier, B., Düllmann, J., Frank, O., Zander, A. R., Ostertag, W. & Baum, C., 09.2002, In: LEUKEMIA. 16, 9, p. 1655-63 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Upstream conserved sequences of mouse leukemia viruses are important for high transgene expression in lymphoid and hematopoietic cells

    Wahlers, A., Kustikova, O., Zipfel, P. F., Itoh, K., Koester, M., Heberlein, C., Li, Z., Schiedlmeier, B., Skerka, C., Fehse, B. & Baum, C., 09.2002, In: MOL THER. 6, 3, p. 313-320 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Murine leukemia induced by retroviral gene marking

    Li, Z., Düllmann, J., Schiedlmeier, B., Schmidt, M., von Kalle, C., Meyer, J., Forster, M., Stocking, C., Wahlers, A., Frank, O., Ostertag, W., Kühlcke, K., Eckert, H-G., Fehse, B. & Baum, C., 19.04.2002, In: SCIENCE. 296, 5567, p. 497

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. Allogeneic stem cell transplantation of adult chronic myelomonocytic leukaemia. A report on behalf of the Chronic Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT).

    Kröger, N., Zabelina, T., Guardiola, P., Volker, R., Sierra, J., Anja, V. B., Niederwieser, D., Zander, A. R. & Theo, D. W., 2002, In: BRIT J HAEMATOL. 118, 1, p. 67-73 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  23. Allogeneic transplantation after reduced conditioning in high risk patients is complicated by a high incidence of acute and chronic graft-versus-host disease.

    Schetelig, J., Kröger, N-M., Held, T. K., Christian, T., Krusch, A., Zabelina, T., Dubiel, M., Rick, O., Bornhäuser, M., Ehninger, G., Zander, A. & Siegert, W., 2002, In: HAEMATOLOGICA. 87, 3, p. 299-305 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma.

    Kröger, N-M., Schwerdtfeger, R., Kiehl, M., Sayer, H. G., Renges, H-H., Zabelina, T., Fehse, B., Tögel, F., Wittkowsky, G., Kuse, R. & Zander, A., 2002, In: BLOOD. 100, 3, p. 755-760 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. Binding of activated platelets to WBCs in vivo after transfusion.

    Gutensohn, K., Geidel, K., Brockmann, M., Siemensen, M., Krueger, W., Kröger, N. & Kuehnl, P., 2002, In: TRANSFUSION. 42, 10, p. 1373-1380 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Dose-reduced conditioning regimen followed by allogeneic stem cell transplantation in patients with myelofibrosis with myeloid metaplasia.

    Hessling, J., Kröger, N-M., Werner, M., Zabelina, T., Hansen, A., Kordes, U., Ayuketang Ayuk, F., Renges, H-H., Panse, J., Erttmann, R. & Zander, A., 2002, In: BRIT J HAEMATOL. 119, 3, p. 769-772 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Highly efficient retroviral gene transfer based on centrifugation-mediated vector preloading of tissue culture vessels.

    Kühlcke, K., Fehse, B., Schilz, A., Loges, S., Lindemann, C., Ayuketang Ayuk, F., Lehmann, F., Stute, N., Fauser, A. A., Zander, A. R. & Eckert, H-G., 2002, In: MOL THER. 5, 4, p. 473-478 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. In vivo T cell depletion with pretransplant anti-thymocyte globulin reduces graft-versus-host disease without increasing relapse in good risk myeloid leukemia patients after stem cell transplantation from matched related donors.

    Kröger, N., Zabelina, T., Krüger, W., Renges, H., Stute, N., Rischewski, J., Sonnenberg, S., Ayuk, F., Ayuketang Ayuk, F., Schade, U., Fiegel, H., Erttmann, R., Löliger, C. & Zander, A. R., 2002, In: BONE MARROW TRANSPL. 29, 8, p. 683-689 8.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  29. Long-term follow-up of allogeneic stem cell transplantation in patients with severe aplastic anemia after conditioning with cyclophosphamide plus antithymocyte globulin.

    Kröger, N., Zabelina, T., Renges, H., Krüger, W., Kordes, U., Rischewski, J., Schrum, J., Horstmann, M., Ayuketang Ayuk, F., Erttmann, R., Kabisch, H. & Zander, A. R., 2002, In: ANN HEMATOL. 81, 11, p. 627-631 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Platelet function testing in apheresis products: flow cytometric, resonance thrombographic (RTG) and rotational thrombelastographic (roTEG) analyses.

    Gutensohn, K., Geidel, K., Kröger, N., Eifrig, B., Crespeigne, N. & Kuehnl, P., 2002, In: TRANSFUS APHER SCI. 26, 3, p. 147-155 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Radiotherapy after high-dose chemotherapy and peripheral blood stem cell support in high-risk breast cancer.

    Hoeller, U., Juergen, H., Kröger, N., Krueger, W., Jaenicke, F. & Alberti, W., 2002, In: INT J RADIAT ONCOL. 53, 5, p. 1234-1239 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Reconstitution of mRNA editing in yeast using a Gal4-apoB-Gal80 fusion transcript as the selectable marker.

    Lellek, H., Welker, S., Diehl, I., Kirsten, R. & Greeve, J., 2002, In: J BIOL CHEM. 277, 26, p. 23638-23644 26.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. [Unrelated donor stem cell transplantation in children: low toxicity using a GvHD-prophylaxis regimen with CSA, MTX, metronidazole,iv-immunoglobulin and ATG]

    Graf Finckenstein, F., Zabelina, T., Dürken, M., Dahlke, J., Kröger, N., Krüger, W., Janka-Schaub, G., Erttmann, R., Zander, A. R. & Kabisch, H., 2002, In: KLIN PADIATR. 214, 4, p. 206-211 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  34. Unrelated stem cell transplantation in multiple myeloma after a reduced-intensity conditioning with pretransplantation antithymocyte globulin is highly effective with low transplantation-related mortality.

    Kröger, N., Sayer, H. G., Schwerdtfeger, R., Kiehl, M., Nagler, A., Renges, H., Zabelina, T., Fehse, B., Ayuketang Ayuk, F., Wittkowsky, G., Schmitz, N. & Zander, A. R., 2002, In: BLOOD. 100, 12, p. 3919-3924 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. 2001

  36. Noncutaneous varicella-zoster virus (VZV) infection with fatal liver failure in a child with acute lymphoblastic leukemia (ALL)

    Müller, I., Aepinus, C., Beck, R., Bültmann, B., Niethammer, D. & Klingebiel, T., 08.2001, In: Med Pediatr Oncol. 37, 2, p. 145-7 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Mass-spectrometry-linked screening of protein fractions for enzymatic activities--a tool for functional genomics

    Jankowski, J., Stephan, N., Knobloch, M., Fischer, S., Schmaltz, D., Zidek, W. & Schlüter, H., 03.2001, In: ANAL BIOCHEM. 290, 2, p. 324-9 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. Membrane-anchored peptide inhibits human immunodeficiency virus entry

    Hildinger, M., Dittmar, M. T., Schult-Dietrich, P., Fehse, B., Schnierle, B. S., Thaler, S., Stiegler, G., Welker, R. & von Laer, D., 03.2001, In: J VIROL. 75, 6, p. 3038-42 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro

    Horn, S., Meyer, J., Heukeshoven, J., Fehse, B., Schulze, C., Li, S., Frey, J., Poll, S., Stocking, C. & Jücker, M., 01.2001, In: LEUKEMIA. 15, 1, p. 112-20 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  40. A fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome.

    Kröger, N., Schetelig, J., Zabelina, T., Krüger, W., Renges, H., Stute, N., Schrum, J., Kabisch, H., Siegert, W. & Zander, A. R., 2001, In: BONE MARROW TRANSPL. 28, 7, p. 643-647 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Anti-thymocyte-globulin as part of the preparative regimen prevents graft failure and severe graft versus host disease (GvHD) in allogeneic stem cell transplantation from unrelated donors.

    Kröger, N., Zabelina, T., Krüger, W., Renges, H., Stute, N., Dürken, M., Graf von Finkenstein, F., Erttmann, R., Kabisch, H., Schafhausen, P., Jaburg, N., Löliger, C. & Zander, A. R., 2001, In: ANN HEMATOL. 80, 4, p. 209-215 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. Comparison of total body irradiation vs busulfan in combination with cyclophosphamide as conditioning for unrelated stem cell transplantation in CML patients.

    Kröger, N., Zabelina, T., Krüger, W., Renges, H., Stute, N., Kabisch, H., Jaburg, N., Löliger, C., Krüll, A. & Zander, A. R., 2001, In: BONE MARROW TRANSPL. 27, 4, p. 349-354 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Donor lymphocyte infusion enhances remission status in patients with persistent disease after allografting for multiple myeloma.

    Kröger, N., Krüger, W., Renges, H., Zabelina, T., Stute, N., Jung, R., Wittkowsky, G., Kuse, R. & Zander, A., 2001, In: BRIT J HAEMATOL. 112, 2, p. 421-423 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. Patient cytomegalovirus seropositivity with or without reactivation is the most important prognostic factor for survival and treatment-related mortality in stem cell transplantation from unrelated donors using pretransplant in vivo T-cell depletion with anti-thymocyte globulin.

    Kröger, N., Zabelina, T., Krüger, W., Renges, H., Stute, N., Schrum, J., Kabisch, H., Schafhausen, P., Jaburg, N., Löliger, C., Schäfer, P., Hinke, A. & Zander, A. R., 2001, In: BRIT J HAEMATOL. 113, 4, p. 1060-1071 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Real-time quantitative Y chromosome-specific PCR (QYCS-PCR) for monitoring hematopoietic chimerism after sex-mismatched allogeneic stem cell transplantation.

    Fehse, B., Chukhlovin, A., Kühlcke, K., Marinetz, O., Vorwig, O., Renges, H., Krüger, W., Zabelina, T., Dudina, O., Finckenstein, F. G., Kröger, N., Kabisch, H., Hochhaus, A. & Zander, A. R., 2001, In: J HEMATOTH STEM CELL. 10, 3, p. 419-425 3.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. T lymphocytes as targets of gene transfer with Moloney-type retroviral vectors.

    Ayuketang Ayuk, F., Zander, A. R. & Fehse, B., 2001, In: CURR GENE THER. 1, 4, p. 325-337 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. 2000

  48. Generation of functionally mature dendritic cells from the multipotential stem cell line FDCP-mix

    Schroeder, T., Strehl, J., Lange, C. & Just, U., 01.12.2000, In: BRIT J HAEMATOL. 111, 3, p. 890-7 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  49. In vitro-generated stem cell leukaemia showing altered cell cycle progression with distinct signalling of the tyrosine-phosphorylated rasGAP-associated p62(dok) protein

    Huss, R., Weissinger, E. M., Lange, C., Gatsios, P., Eissner, G., Kolb, H. J., Diebold, J., Heinrich, P. C. & Graeve, L., 01.11.2000, In: J PATHOL. 192, 3, p. 363-72 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. Quiescence of CD34-negative haematopoietic stem cells is mediated by downregulation of Cyclin B and no stat activation

    Huss, R., Gatsios, P., Graeve, L., Lange, C., Eissner, G., Kolb, H. J., Thalmeier, K. & Heinrich, P. C., 01.08.2000, In: CYTOKINE. 12, 8, p. 1195-204 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. CD34 splice variant: an attractive marker for selection of gene-modified cells

    Fehse, B., Richters, A., Putimtseva-Scharf, K., Klump, H., Li, Z., Ostertag, W., Zander, A. R. & Baum, C., 05.2000, In: MOL THER. 1, 5 Pt 1, p. 448-456 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Evidence of peripheral blood-derived, plastic-adherent CD34(-/low) hematopoietic stem cell clones with mesenchymal stem cell characteristics

    Huss, R., Lange, C., Weissinger, E. M., Kolb, H. J. & Thalmeier, K., 01.01.2000, In: STEM CELLS. 18, 4, p. 252-60 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. Dose-dependent effect of etoposide in combination with busulfan plus cyclophosphamide as conditioning for stem cell transplantation in patients with acute myeloid leukemia.

    Kröger, N., Zabelina, T., Sonnenberg, S., Krüger, W., Renges, H., Stute, N., Finkenstein, F., Mayer, U., Holstein, K., Fiedler, W., Colberg, H., Sonnen, R., Kuse, R., Braumann, D., Metzner, B., Del Valle, F., Erttmann, R., Kabisch, H. & Zander, A. R., 2000, In: BONE MARROW TRANSPL. 26, 7, p. 711-716 7.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. Extracorporeal plateletpheresis induces the interaction of activated platelets with white blood cells.

    Gutensohn, K., Alisch, A., Krueger, W., Kröger, N. & Kuehnl, P., 2000, In: VOX SANG. 78, 2, p. 101-105 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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