Department of Tumor Biology
Publications
- 2017
Strong fascin expression promotes metastasis independent of its F-actin bundling activity
Heinz, L. S., Muhs, S., Schiewek, J., Grüb, S., Nalaskowski, M., Lin, Y-N., Wikman, H., Oliveira-Ferrer, L., Lange, T., Wellbrock, J., Konietzny, A., Mikhaylova, M. & Windhorst, S., 15.12.2017, In: ONCOTARGET. 8, 66, p. 110077-110091 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Evaluation of serum epidermal growth factor receptor (EGFR) in correlation to circulating tumor cells in patients with metastatic breast cancer
Banys-Paluchowski, M., Witzel, I., Riethdorf, S., Rack, B., Janni, W., Fasching, P. A., Solomayer, E-F., Aktas, B., Kasimir-Bauer, S., Pantel, K., Fehm, T. & Müller, V., 11.12.2017, In: SCI REP-UK. 7, 1, p. Art. 17307Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy
Zheng, H., Bae, Y., Kasimir-Bauer, S., Tang, R., Chen, J., Ren, G., Yuan, M., Esposito, M., Li, W., Wei, Y., Shen, M., Zhang, L., Tupitsyn, N., Pantel, K., King, C., Sun, J., Moriguchi, J., Jun, H. T., Coxon, A., Lee, B. & Kang, Y., 11.12.2017, In: CANCER CELL. 32, 6, p. 731-747.e6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of Circulating Plasma Cells in Multiple Myeloma
Alix-Panabières, C. & Pantel, K., 12.2017, In: CLIN CHEM. 63, 12, p. 1797-1798Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
The current status and clinical value of circulating tumor cells and circulating cell-free tumor DNA in bladder cancer
Riethdorf, S., Soave, A. & Rink, M., 12.2017, In: TRANSL ANDROL UROL. 6, 6, p. 1090-1110 21 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Tracing the Seeds in the Soil
Werner, S. & Pantel, K., 11.2017, In: CLIN CHEM. 63, 11, p. 1764-1765Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Circulating tumor cells as liquid biomarker for high HCC recurrence risk after curative liver resection
von Felden, J., Schulze, K., Krech, T., Ewald, F., Nashan, B., Pantel, K., Lohse, A. W., Riethdorf, S. & Wege, H., 27.10.2017, In: ONCOTARGET. 8, 52, p. 89978-89987 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of BRCA1 promotor hypermethylation in recurrent high-grade ovarian cancer
Prieske, K., Prieske, S., Joosse, S. A., Trillsch, F., Grimm, D., Burandt, E., Mahner, S., Schmalfeldt, B., Milde-Langosch, K., Oliveira-Ferrer, L. & Woelber, L., 10.10.2017, In: ONCOTARGET. 8, 47, p. 83063-83074 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Immunotherapy of WAP-TNP mice with early stage mammary gland tumors
Bruns, M. & Deppert, W., 15.09.2017, In: ONCOTARGET. 8, 40, p. 67790-67804Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plasma microRNA signature is associated with risk stratification in prostate cancer patients
Al-Qatati, A., Akrong, C., Stevic, I., Pantel, K., Awe, J., Saranchuk, J., Drachenberg, D., Mai, S. & Schwarzenbach, H., 15.09.2017, In: INT J CANCER. 141, 6, p. 1231-1239 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prognostic impact of circulating tumor cells for breast cancer patients treated in the neoadjuvant "Geparquattro" trial
Riethdorf, S., Müller, V., Loibl, S., Nekljudova, V., Weber, K. E., Huober, J., Fehm, T., Schrader, I., Hilfrich, J., Holms, F., Tesch, H., Schem, C., von Minckwitz, G., Untch, M. & Pantel, K., 15.09.2017, In: CLIN CANCER RES. 23, 18, p. 5384-5393Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Management immunvermittelter Nebenwirkungen - CME Fortbildung
Janning, M. & Loges, S., 09.2017, In: InFo Onkologie. 20, S1, p. 54-64Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells
Babayan, A., Alawi, M., Gormley, M., Müller, V., Wikman, H., McMullin, R. P., Smirnov, D. A., Li, W., Geffken, M., Pantel, K. & Joosse, S. A., 22.08.2017, In: ONCOTARGET. 8, 34, p. 56066-56080 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Copy number variations of circulating, cell-free DNA in urothelial carcinoma of the bladder patients treated with radical cystectomy: a prospective study
Soave, A., Chun, F. K-H., Hillebrand, T., Rink, M., Weisbach, L., Steinbach, B., Fisch, M., Pantel, K. & Schwarzenbach, H., 22.08.2017, In: ONCOTARGET. 8, 34, p. 56398-56407 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B
Wroblewski, M., Bauer, R., Cubas Córdova, M., Udonta, F., Ben-Batalla, I., Legler, K., Hauser, C., Egberts, J., Janning, M., Velthaus, J., Schulze, C., Pantel, K., Bokemeyer, C. & Loges, S., 16.08.2017, In: NAT COMMUN. 8, 1, p. 269Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating Tumour Cell Release after Cement Augmentation of Vertebral Metastases
Mohme, M., Riethdorf, S., Dreimann, M., Werner, S., Maire, C. L., Joosse, S. A., Bludau, F., Mueller, V., Neves, R. P. L., Stoecklein, N. H., Lamszus, K., Westphal, M., Pantel, K., Wikman, H. & Eicker, S. O., 03.08.2017, In: SCI REP-UK. 7, 1, p. 7196Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biology and clinical significance of circulating tumor cell subpopulations in lung cancer
O'Flaherty, L., Wikman, H. & Pantel, K., 08.2017, In: TRANSL LUNG CANCER R. 6, 4, p. 431-443 13 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Nanoplatforms for Circulating Tumor Cell Detection in Lung Cancer
Wikman, H. & Pantel, K., 08.2017, In: CLIN CHEM. 63, 8, p. 1318-1320 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Biological Labels: Here comes the spaser
Alix-Panabières, C. & Pantel, K., 26.07.2017, In: NAT MATER. 16, 8, p. 790-791 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Implementing liquid biopsies into clinical decision making for cancer immunotherapy
Quandt, D., Dieter Zucht, H., Amann, A., Wulf-Goldenberg, A., Borrebaeck, C., Cannarile, M., Lambrechts, D., Oberacher, H., Garrett, J., Nayak, T., Kazinski, M., Massie, C., Schwarzenbach, H., Maio, M., Prins, R., Wendik, B., Hockett, R., Enderle, D., Noerholm, M., Hendriks, H., Zwierzina, H. & Seliger, B., 18.07.2017, In: ONCOTARGET. 8, 29, p. 48507-48520 14 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Hamburg-Glasgow classification: preoperative staging by combination of disseminated tumour load and systemic inflammation in oesophageal carcinoma
Reeh, M., Ghadban, T., Uzunoglu, F. G., Nentwich, M. F., Bockhorn, M., Pantel, K., Izbicki, J. R. & Vashist, Y. K., 13.07.2017, In: BRIT J CANCER. 117, 5, p. 612-618Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Prevalence of Circulating Tumor Cells After Adjuvant Chemotherapy With or Without Anthracyclines in Patients With HER2-negative, Hormone Receptor-positive Early Breast Cancer
Schramm, A., Schochter, F., Friedl, T. W. P., de Gregorio, N., Andergassen, U., Alunni-Fabbroni, M., Trapp, E., Jaeger, B., Heinrich, G., Camara, O., Decker, T., Ober, A., Mahner, S., Fehm, T. N., Pantel, K., Fasching, P. A., Schneeweiss, A., Janni, W., Rack, B. K. & SUCCESS Study Group, 07.2017, In: CLIN BREAST CANCER. 17, 4, p. 279-285Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer stem cells: The root of tumor recurrence and metastases
Peitzsch, C., Tyutyunnykova, A., Pantel, K. & Dubrovska, A., 06.2017, In: SEMIN CANCER BIOL. 44, p. 10-24 15 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Clinical Relevance of Serum HER2 and Circulating Tumor Cell Detection in Metastatic Breast Cancer Patients
Banys-Paluchowski, M., Witzel, I., Riethdorf, S., Rack, B., Janni, W., Fasching, P. A., Solomayer, E-F., Aktas, B., Kasimir-Bauer, S., Pantel, K., Fehm, T. & Müller, V., 06.2017, In: ANTICANCER RES. 37, 6, p. 3117-3128 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection and oncological effect of circulating tumour cells in patients with variant urothelial carcinoma histology treated with radical cystectomy
Soave, A., Riethdorf, S., Dahlem, R., Minner, S., Weisbach, L., Engel, O., Fisch, M., Pantel, K. & Rink, M., 06.2017, In: BJU INT. 119, 6, p. 854-861 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumour microenvironment: informing on minimal residual disease in solid tumours
Pantel, K. & Alix-Panabières, C., 06.2017, In: NAT REV CLIN ONCOL. 14, 6, p. 325-326 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia
Ben Batalla, I., Erdmann, R., Jørgensen, H., Mitchell, R., Ernst, T., von Amsberg, G., Schafhausen, P., Velthaus, J. L., Rankin, S., Clark, R. E., Koschmieder, S., Schultze, A., Mitra, S., Vandenberghe, P., Brümmendorf, T. H., Carmeliet, P., Hochhaus, A., Pantel, K., Bokemeyer, C., Helgason, G. V., Holyoake, T. L. & Loges, S., 01.05.2017, In: CLIN CANCER RES. 23, 9, p. 2289-2300Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells
Nagarajan, S., Bedi, U., Budida, A., Hamdan, F. H., Mishra, V. K., Najafova, Z., Xie, W., Alawi, M., Indenbirken, D., Knapp, S., Chiang, C-M., Grundhoff, A., Kari, V., Scheel, C. H., Wegwitz, F. & Johnsen, S. A., 07.04.2017, In: NUCLEIC ACIDS RES. 45, 6, p. 3130-3145 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PLA2G7 associates with hormone receptor negativity in clinical breast cancer samples and regulates epithelial-mesenchymal transition in cultured breast cancer cells
Lehtinen, L., Vainio, P., Wikman, H., Huhtala, H., Mueller, V., Kallioniemi, A., Pantel, K., Kronqvist, P., Kallioniemi, O., Carpèn, O. & Iljin, K., 04.2017, In: J PATHOL CLIN RES. 3, 2, p. 123-138 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of HYAL1 expression in primary breast cancer in the formation of brain metastases
Witzel, I., Marx, A. K., Müller, V., Wikman, H., Matschke, J., Schumacher, U., Stürken, C., Prehm, P., Laakmann, E., Schmalfeldt, B., Milde-Langosch, K. & Oliveira-Ferrer, L., 04.2017, In: BREAST CANCER RES TR. 162, 3, p. 427-438 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism
Braig, F., Kriegs, M., Voigtlaender, M., Habel, B., Grob, T., Biskup, K., Blanchard, V., Sack, M., Thalhammer, A., Ben Batalla, I., Braren, I., Laban, S., Danielczyk, A., Goletz, S., Jakubowicz, E., Märkl, B., Trepel, M., Knecht, R., Riecken, K., Fehse, B., Loges, S., Bokemeyer, C. & Binder, M., 01.03.2017, In: CANCER RES. 77, 5, p. 1188-1199 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating and disseminated tumour cells - mechanisms of immune surveillance and escape
Mohme, M., Riethdorf, S. & Pantel, K., 03.2017, In: NAT REV CLIN ONCOL. 14, 3, p. 155-167Research output: SCORING: Contribution to journal › SCORING: Review article › Research
A combination of low-dose bevacizumab and imatinib enhances vascular normalisation without inducing extracellular matrix deposition
Schiffmann, L. M., Brunold, M., Liwschitz, M., Goede, V., Loges, S., Wroblewski, M., Quaas, A., Alakus, H., Stippel, D., Bruns, C. J., Hallek, M., Kashkar, H., Hacker, U. T. & Coutelle, O., 28.02.2017, In: BRIT J CANCER. 116, 5, p. 600-608 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Catch and Release: rare cell analysis from a functionalised medical wire
Chen, S., El-Heliebi, A., Tauber, G., Langsenlehner, T., Pötscher, M., Kashofer, K., Czyż, Z. T., Polzer, B., Riethdorf, S., Kuske, A., Leitinger, G., Pantel, K., Kroneis, T. & Sedlmayr, P., 24.02.2017, In: SCI REP-UK. 7, p. 43424Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liquid Biopsies, What We Do Not Know (Yet)
Bardelli, A. & Pantel, K., 13.02.2017, In: CANCER CELL. 31, 2, p. 172-179 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epithelial-mesenchymal plasticity in circulating tumor cells
Alix-Panabières, C., Mader, S. & Pantel, K., 02.2017, In: J MOL MED. 95, 2, p. 133-142 10 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Liquid biopsy in 2016: Circulating tumour cells and cell-free DNA in gastrointestinal cancer
Pantel, K. & Alix-Panabières, C., 02.2017, In: NAT REV GASTRO HEPAT. 14, 2, p. 73-74 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
A nonrandomized, prospective, clinical study on the impact of circulating tumor cells on outcomes of urothelial carcinoma of the bladder patients treated with radical cystectomy with or without adjuvant chemotherapy
Soave, A., Riethdorf, S., Dahlem, R., von Amsberg, G., Minner, S., Weisbach, L., Engel, O., Fisch, M., Pantel, K. & Rink, M., 15.01.2017, In: INT J CANCER. 140, 2, p. 381-389 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PTEN mediates the cross talk between breast and glial cells in brain metastases leading to rapid disease progression
Hohensee, I., Chuang, H-N., Grottke, A., Werner, S., Schulte, A., Horn, S., Lamszus, K., Bartkowiak, K., Witzel, I., Westphal, M., Matschke, J., Glatzel, M., Jücker, M., Pukrop, T., Pantel, K. & Wikman, H., 01.2017, In: ONCOTARGET. 8, 4, p. 6155-6168Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of Single Circulating Tumor Cells
Alix-Panabières, C. & Pantel, K., 2017, In: FEBS LETT. 591, 15, p. 2241 - 2250Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical Relevance of Circulating, Cell-Free and Exosomal microRNAs in Plasma and Serum of Breast Cancer Patients
Schwarzenbach, H., 2017, In: ONCOL RES TREAT. 40, 7-8, p. 423-429 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Discordance in Human Epidermal Growth Factor Receptor 2 (HER2) Phenotype Between Primary Tumor and Circulating Tumor Cells in Women With HER2-Negative Metastatic Breast Cancer
de Gregorio, A., Friedl, T. W. P., Huober, J., Scholz, C., de Gregorio, N., Rack, B., Trapp, E., Alunni-Fabbroni, M., Riethdorf, S., Muller, V., Schneeweiss, A., Pantel, K., Meier-Stiegen, F., Jaeger, B., Hartkopf, A., Taran, F-A., Fasching, P. A., Janni, W. & Fehm, T., 2017, In: JCO PRECIS ONCOL. 2017, 1, p. 1-12Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of Epithelial Mesenchymal Transition and Cancer Stem Cell Markers in Circulating Tumor Cells
Werner, S., Stenzl, A., Pantel, K. & Todenhöfer, T., 2017, In: ADV EXP MED BIOL. 994, p. 205-228 24 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liquid Biopsy: Current Status and Future Perspectives
Mader, S. & Pantel, K., 2017, In: ONCOL RES TREAT. 40, 7-8, p. 404-408 5 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Prenatal Administration of Betamethasone Causes Changes in the T Cell Receptor Repertoire Influencing Development of Autoimmunity
Gieras, A., Gehbauer, C., Perna-Barrull, D., Engler, J. B., Diepenbruck, I., Glau, L., Joosse, S. A., Kersten, N., Klinge, S., Mittrücker, H-W., Friese, M. A., Vives-Pi, M. & Tolosa, E., 2017, In: FRONT IMMUNOL. 8, p. 1505Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The HER2 phenotype of circulating tumor cells in HER2-positive early breast cancer: A translational research project of a prospective randomized phase III trial
Jaeger, B. A. S., Neugebauer, J., Andergassen, U., Melcher, C., Schochter, F., Mouarrawy, D., Ziemendorff, G., Clemens, M., V Abel, E., Heinrich, G., Schueller, K., Schneeweiss, A., Fasching, P., Beckmann, M. W., Scholz, C., Friedl, T. W. P., Friese, K., Pantel, K., Fehm, T., Janni, W. & Rack, B., 2017, In: PLOS ONE. 12, 6, p. e0173593Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2016
Improved detection of circulating tumor cells in non-metastatic high-risk prostate cancer patients
Kuske, A., Gorges, T. M., Tennstedt, P., Tiebel, A-K., Pompe, R., Preißer, F., Prues, S., Mazel, M., Markou, A., Lianidou, E., Peine, S., Alix-Panabières, C., Riethdorf, S., Beyer, B., Schlomm, T. & Pantel, K., 21.12.2016, In: SCI REP-UK. 6, p. 39736Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blood-Based Analysis of Circulating Cell-Free DNA and Tumor Cells for Early Cancer Detection
Pantel, K., 12.2016, In: PLOS MED. 13, 12, p. e1002205Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Cancer immunotherapy: weak beats strong
Deppert, W. & Bruns, M., 30.11.2016, In: AGING-US. 8, 11, p. 2607-2608 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells
Gorges, T. M., Kuske, A., Röck, K., Mauermann, O., Müller, V., Peine, S., Verpoort, K., Novosadova, V., Kubista, M., Riethdorf, S. & Pantel, K., 11.2016, In: CLIN CHEM. 62, 11, p. 1504-1515 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review