Department of Tumor Biology
Publications
- 2016
Biological and Clinical Relevance of H19 in Colorectal Cancer Patients
Schwarzenbach, H., 11.2016, In: EBIOMEDICINE. 13, p. 9-10 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Impact of apoptotic circulating tumor cells (aCTC) in metastatic breast cancer
Deutsch, T. M., Riethdorf, S., Nees, J., Hartkopf, A. D., Schönfisch, B., Domschke, C., Sprick, M. R., Schütz, F., Brucker, S. Y., Stefanovic, S., Sohn, C., Pantel, K., Trumpp, A., Schneeweiss, A. & Wallwiener, M., 11.2016, In: BREAST CANCER RES TR. 160, 2, p. 277-290 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness
Kari, V., Mansour Khalfallah, W. Y., Raul, S. K., Baumgart, S. J., Mund, A., Grade, M., Sirma, H., Simon, R., Will, H., Dobbelstein, M., Dikomey, E. & Johnsen, S. A., 11.2016, In: EMBO REP. 17, 11, p. 1609-1623 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Antibody production using a ciliate generates unusual antibody glycoforms displaying enhanced cell-killing activity
Calow, J., Behrens, A-J., Mader, S., Bockau, U., Struwe, W. B., Harvey, D. J., Cormann, K. U., Nowaczyk, M. M., Loser, K., Schinor, D., Hartmann, M. W. W. & Crispin, M., 30.10.2016, In: MABS-AUSTIN. 8, 8, p. 1498-1511 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cancer: A shocking protein complex
Bartkowiak, K. & Pantel, K., 20.10.2016, In: NATURE. 538, 7625, p. 322-323 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Frequent detection of PIK3CA mutations in single circulating tumor cells of patients suffering from HER2-negative metastatic breast cancer
Gasch, C., Oldopp, T., Mauermann, O., Gorges, T. M., Andreas, A., Coith, C., Müller, V., Fehm, T., Janni, W., Pantel, K. & Riethdorf, S., 10.2016, In: MOL ONCOL. 10, 8, p. 1330-43 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liquid biopsies for surveillance and monitoring treatment response of bladder cancer
Riethdorf, S. & Pantel, K., 10.2016, In: J TRANSL MED. 4, 19, p. 379Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo
Wegwitz, F., Lenfert, E., Gerstel, D., von Ehrenstein, L., Einhoff, J., Schmidt, G., Logsdon, M., Brandner, J., Tiegs, G., Beauchemin, N., Wagener, C., Deppert, W. & Horst, A. K., 27.09.2016, In: ONCOTARGET. 7, 39, p. 63730-63746Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TAM receptors Tyro3 and Mer as novel targets in colorectal cancer
Schmitz, R., Valls, A. F., Yerbes, R., von Richter, S., Kahlert, C., Loges, S., Weitz, J., Schneider, M., Ruiz de Almodovar, C., Ulrich, A. & Schmidt, T., 30.08.2016, In: ONCOTARGET. 7, 35, p. 56355-56370 16 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating Tumor DNA as a Cancer Biomarker: Fact or Fiction?
Leung, F., Kulasingam, V., Diamandis, E. P., Hoon, D. S. B., Kinzler, K., Pantel, K. & Alix-Panabières, C., 08.2016, In: CLIN CHEM. 62, 8, p. 1054-60 7 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Liquid biopsy-based clinical research in early breast cancer: The EORTC 90091-10093 Treat CTC trial
Ignatiadis, M., Rack, B., Rothé, F., Riethdorf, S., Decraene, C., Bonnefoi, H., Dittrich, C., Messina, C., Beauvois, M., Trapp, E., Goulioti, T., Tryfonidis, K., Pantel, K., Repollet, M., Janni, W., Piccart, M., Sotiriou, C., Litiere, S. & Pierga, J-Y., 08.2016, In: EUR J CANCER. 63, p. 97-104 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TP53 mutations on circulating cell-free DNA
Pantel, K., 08.2016, In: EBIOMEDICINE. 10, p. 15-6 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Heterogeneous PSMA expression on circulating tumor cells - a potential basis for stratification and monitoring of PSMA-directed therapies in prostate cancer
Gorges, T. M., Riethdorf, S., von Ahsen, O., Nastały, P., Röck, K., Boede, M., Peine, S., Kuske, A., Schmid, E., Kneip, C., König, F., Rudolph, M. & Pantel, K., 07.06.2016, In: ONCOTARGET. 7, 23, p. 34930-41Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plasma Hyaluronic Acid level as a Prognostic and Monitoring Marker of Metastatic Breast Cancer
Peng, C., Wallwiener, M., Rudolph, A., Ćuk, K., Eilber, U., Celik, M., Modugno, C., Trumpp, A., Heil, J., Marmé, F., Madhavan, D., Nees, J., Riethdorf, S., Schott, S., Sohn, C., Pantel, K., Schneeweiss, A., Chang-Claude, J., Yang, R. & Burwinkel, B., 15.05.2016, In: INT J CANCER. 138, 10, p. 2499-509Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Plasma S100P level as a novel prognostic marker of metastatic breast cancer
Peng, C., Chen, H., Wallwiener, M., Modugno, C., Cuk, K., Madhavan, D., Trumpp, A., Heil, J., Marmé, F., Nees, J., Riethdorf, S., Schott, S., Sohn, C., Pantel, K., Schneeweiss, A., Yang, R. & Burwinkel, B., 04.05.2016, In: BREAST CANCER RES TR. 157, 2, p. 329-38Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Enumeration and molecular characterization of tumor cells in lung cancer patients using a novel in vivo device for capturing circulating tumor cells
Gorges, T. M., Penkalla, N., Schalk, T., Joosse, S., Riethdorf, S., Tucholski, J., Lucke, K., Wikman, H., Jackson, S. M., Brychter, N., von Ahsen, O., Schumann, C., Krahn, T. & Pantel, K., 01.05.2016, In: CLIN CANCER RES. 22, 9, p. 2197-206Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Limited prognostic value of preoperative circulating tumor cells for early biochemical recurrence in patients with localized prostate cancer
Meyer, C. P., Pantel, K., Tennstedt, P., Stroelin, P., Schlomm, T., Heinzer, H., Riethdorf, S. & Steuber, T., 01.05.2016, In: UROL ONCOL-SEMIN ORI. 34, 5, p. 235.e11-6Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Pooled Analysis of the Prognostic Relevance of Circulating Tumor Cells in Primary Breast Cancer
Janni, W., Rack, B., Terstappen, L. W., Pierga, J-Y., Taran, F-A., Fehm, T., Hall, C., de Groot, M., Bidard, F-C., Friedl, T. W. P., Fasching, P. A., Brucker, S. Y., Pantel, K. & Lucci, A., 01.05.2016, In: CLIN CANCER RES. 22, 10, p. 2583-93Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy
Alix-Panabières, C. & Pantel, K., 05.2016, In: CANCER DISCOV. 6, 5, p. 479-91 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Imaging analysis of nuclear antiviral factors through direct detection of incoming adenovirus genome complexes
Komatsu, T., Will, H., Nagata, K. & Wodrich, H., 22.04.2016, In: BIOCHEM BIOPH RES CO. 473, 1, p. 200-5 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Perspectives on sipuleucel-T: Its role in the prostate cancer treatment paradigm
Gulley, J. L., Mulders, P., Albers, P., Banchereau, J., Bolla, M., Pantel, K. & Powles, T., 04.2016, In: ONCOIMMUNOLOGY. 5, 4, p. e1107698Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnostic and prognostic relevance of circulating exosomal miR-373, miR-200a, miR-200b and miR-200c in patients with epithelial ovarian cancer
Meng, X., Müller, V., Milde-Langosch, K., Trillsch, F., Pantel, K. & Schwarzenbach, H., 29.03.2016, In: ONCOTARGET. 7, 13, p. 16923-35Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional studies on circulating and disseminated tumor cells in carcinoma patients
Alix-Panabières, C., Bartkowiak, K. & Pantel, K., 03.2016, In: MOL ONCOL. 10, 3, p. 443-9 7 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Genetic traits for hematogeneous tumor cell dissemination in cancer patients
Joosse, S. A. & Pantel, K., 03.2016, In: CANCER METAST REV. 35, 1, p. 41-8 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Liquid biopsy: Potential and challenges
Pantel, K. & Alix-Panabières, C., 03.2016, In: MOL ONCOL. 10, 3, p. 371-3 3 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Diverse prognostic value of the GTn promoter polymorphism in squamous cell and adeno carcinoma of the esophageus
Ghadban, T., Miro, J. T., Trump, F., Tsui, T. Y., Uzunoglu, F. G., Reeh, M., Gebauer, F., Bachmann, K., Wellner, U., Kalinin, V., Pantel, K., Izbicki, J. R. & Vashist, Y. K., 25.02.2016, In: CLIN GENET. 90, 4, p. 343-50Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RHAMM splice variants confer radiosensitivity in human breast cancer cell lines
Schütze, A., Vogeley, C., Gorges, T., Twarock, S., Butschan, J., Babayan, A., Klein, D., Knauer, S. K., Metzen, E., Müller, V., Jendrossek, V., Pantel, K., Milde-Langosch, K., Fischer, J. W. & Röck, K., 08.02.2016, In: ONCOTARGET. 7, 16, p. 21428-40Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional Studies on Viable Circulating Tumor Cells
Pantel, K. & Alix-Panabières, C., 02.2016, In: CLIN CHEM. 62, 2, p. 328-34Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Potential Involvement of Jagged1 in Metastatic Progression of Human Breast Carcinomas
Bednarz-Knoll, N., Efstathiou, A., Gotzhein, F., Wikman, H., Mueller, V., Kang, Y. & Pantel, K., 02.2016, In: CLIN CHEM. 62, 2, p. 378-386Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Potential of circulating tumor cells as blood-based biomarkers in cancer liquid biopsy
Schlange, T. & Pantel, K., 02.2016, In: PHARMACOGENOMICS. 17, 3, p. 183-6 4 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Therapeutic intervention based on circulating tumor cell phenotype in metastatic breast cancer: concept of the DETECT study program
Schramm, A., Friedl, T. W. P., Schochter, F., Scholz, C., de Gregorio, N., Huober, J., Rack, B., Trapp, E., Alunni-Fabbroni, M., Müller, V., Schneeweiss, A., Pantel, K., Meier-Stiegen, F., Hartkopf, A., Taran, F-A., Wallwiener, D., Janni, W. & Fehm, T., 02.2016, In: ARCH GYNECOL OBSTET. 293, 2, p. 271-81Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A novel microfluidic platform for size and deformability based separation and the subsequent molecular characterization of viable circulating tumor cells
Hvichia, G. E., Parveen, Z., Wagner, C., Janning, M., Quidde, J., Stein, A., Müller, V., Loges, S., Neves, R. P. L., Stoecklein, N. H., Wikman, H., Riethdorf, S., Pantel, K. & Gorges, T. M., 20.01.2016, In: INT J CANCER. 138, 12, p. 2894-904Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Breast cancer brain metastases:biology and new clinical perspectives
Witzel, I., Oliveira-Ferrer, L., Pantel, K., Müller, V. & Wikman, H., 19.01.2016, In: BREAST CANCER RES. 18, 1, p. 8Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homogenization of tissues via picosecond-infrared laser (PIRL) ablation: Giving a closer view on the in-vivo composition of protein species as compared to mechanical homogenization
Kwiatkowski, M., Wurlitzer, M., Krutilin, A., Kiani, P., Nimer, R., Omidi, M., Mannaa, A., Bussmann, T., Bartkowiak, K., Kruber, S., Uschold, S., Steffen, P., Lübberstedt, J., Küpker, N., Petersen, H., Knecht, R., Hansen, N. O., Zarrine-Afsar, A., Robertson, W. D., Miller, R. J. D. & Schlüter, H., 08.01.2016, In: J PROTEOMICS. 134, p. 193-202Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Characterization of different CTC subpopulations in non-small cell lung cancer
Hanssen, A., Wagner, J., Gorges, T. M., Tänzer, A., Uzunoglu, F. G., Driemel, C., Stoecklein, N. H., Knoefel, W. T., Angenendt, S., Hauch, S., Atanackovic, D., Loges, S., Riethdorf, S., Pantel, K. & Wikman, H., 2016, In: SCI REP-UK. 6, p. 28010Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chronic UVB-irradiation actuates perpetuated dermal matrix remodeling in female mice: Protective role of estrogen
Röck, K., Joosse, S. A., Müller, J., Heinisch, N., Fuchs, N., Meusch, M., Zipper, P., Reifenberger, J., Pantel, K. & Fischer, J. W., 2016, In: SCI REP-UK. 6, p. 30482Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating Cell-Free miR-373, miR-200a, miR-200b and miR-200c in Patients with Epithelial Ovarian Cancer
Meng, X., Müller, V., Milde-Langosch, K., Trillsch, F., Pantel, K. & Schwarzenbach, H., 2016, In: ADV EXP MED BIOL. 924, p. 3-8 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Circulating miRNAs with prognostic value in metastatic breast cancer and for early detection of metastasis
Madhavan, D., Peng, C., Wallwiener, M., Zucknick, M., Nees, J., Schott, S., Rudolph, A., Riethdorf, S., Trumpp, A., Pantel, K., Sohn, C., Chang-Claude, J., Schneeweiss, A. & Burwinkel, B., 2016, In: CARCINOGENESIS. 37, 5, p. 461 - 470Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Clinical significance of miR-15 and miR-16 in ovarian cancer.
Schwarzenbach, H., 2016, In: TRANSL CANCER RES. 5, p. 50-53Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Comparison of the HER2, estrogen and progesterone receptor expression profile of primary tumor, metastases and circulating tumor cells in metastatic breast cancer patients
Aktas, B., Kasimir-Bauer, S., Müller, V., Janni, W., Fehm, T., Wallwiener, D., Pantel, K., Tewes, M. & DETECT Study Group, 2016, In: BMC CANCER. 16, p. 522Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of circulating tumor cells using manually performed immunocytochemistry (MICC) does not correlate with outcome in patients with early breast cancer - Results of the German SUCCESS-A- trial
Jueckstock, J., Rack, B., Friedl, T. W. P., Scholz, C., Steidl, J., Trapp, E., Tesch, H., Forstbauer, H., Lorenz, R., Rezai, M., Häberle, L., Alunni-Fabbroni, M., Schneeweiss, A., Beckmann, M. W., Lichtenegger, W., Fasching, P. A., Pantel, K., Janni, W. & SUCCESS Study Group, 2016, In: BMC CANCER. 16, p. 401Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Diagnostic relevance of circulating cell-free and exosomal microRNAs and long non-coding RNAs in blood of cancer patients.
Schwarzenbach, H., 2016, In: LABORATORIUMSMEDIZIN. 40, 5, p. 345-353Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Improved Detection of Circulating Tumor Cells in Metastatic Colorectal Cancer by the Combination of the CellSearch® System and the AdnaTest®
Gorges, T. M., Stein, A., Quidde, J., Hauch, S., Röck, K., Riethdorf, S., Joosse, S. A. & Pantel, K., 2016, In: PLOS ONE. 11, 5, p. e0155126Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Novel Technology for Enrichment of Biomolecules from Cell-Free Body Fluids and Subsequent DNA Sizing
Patel, V., Celec, P., Grunt, M., Schwarzenbach, H., Jenneckens, I. & Hillebrand, T., 2016, In: ADV EXP MED BIOL. 924, p. 165-169 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
T-cell epitope strength in WAP-T mouse mammary carcinomas is an important determinant in PD1/PD-L1 immune checkpoint blockade therapy
Bruns, M., Wanger, J., Schumacher, U. & Deppert, W., 2016, In: ONCOTARGET. 7, 40, p. 64543 - 64559Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The biology of circulating tumor cells
Pantel, K. & Speicher, M. R., 2016, In: ONCOGENE. 35, 10, p. 1216-24Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2015
Effects of p38α/β inhibition on acute lymphoblastic leukemia proliferation and survival in vivo
Alsadeq, A., Strube, S., Krause, S., Carlet, M., Jeremias, I., Vokuhl, C., Loges, S., Aguirre-Ghiso, J. A., Trauzold, A., Cario, G., Stanulla, M., Schrappe, M. & Schewe, D. M., 29.12.2015, In: LEUKEMIA. 29, 12, p. 2307-16 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Bartkowiak, K., Kwiatkowski, M., Buck, F., Gorges, T. M., Nilse, L., Assmann, V., Andreas, A., Müller, V., Wikman, H., Riethdorf, S., Schlüter, H. & Pantel, K., 15.12.2015, In: CANCER RES. 75, 24, p. 5367-77 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Distribution and prognostic relevance of tumor-infiltrating lymphocytes (TILs) and PD-1/PD-L1 immune checkpoints in human brain metastases
Harter, P. N., Bernatz, S., Scholz, A., Zeiner, P. S., Zinke, J., Kiyose, M., Blasel, S., Beschorner, R., Senft, C., Bender, B., Ronellenfitsch, M. W., Wikman-Kocher, H., Glatzel, M., Meinhardt, M., Juratli, T. A., Steinbach, J. P., Plate, K. H., Wischhusen, J., Weide, B. & Mittelbronn, M., 12.2015, In: ONCOTARGET. 6, 38, p. 40836-40849Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tumour exosome integrins determine organotropic metastasis
Hoshino, A., Costa-Silva, B., Shen, T-L., Rodrigues, G., Hashimoto, A., Tesic Mark, M., Molina, H., Kohsaka, S., Di Giannatale, A., Ceder, S., Singh, S., Williams, C., Soplop, N., Uryu, K., Pharmer, L., King, T., Bojmar, L., Davies, A. E., Ararso, Y., Zhang, T., Zhang, H., Hernandez, J., Weiss, J. M., Dumont-Cole, V. D., Kramer, K., Wexler, L. H., Narendran, A., Schwartz, G. K., Healey, J. H., Sandstrom, P., Jørgen Labori, K., Kure, E. H., Grandgenett, P. M., Hollingsworth, M. A., de Sousa, M., Kaur, S., Jain, M., Mallya, K., Batra, S. K., Jarnagin, W. R., Brady, M. S., Fodstad, O., Muller, V., Pantel, K., Minn, A. J., Bissell, M. J., Garcia, B. A., Kang, Y., Rajasekhar, V. K., Ghajar, C. M., Matei, I., Peinado, H., Bromberg, J. & Lyden, D., 19.11.2015, In: NATURE. 527, 7578, p. 329-35Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review