Department of Tumor Biology

Publications

  1. 2008
  2. Molecular targeted therapies for breast cancer treatment.

    Schlotter, C. M., Vogt, U., Allgayer, H. & Brandt, B., 2008, In: BREAST CANCER RES. 10, 4, p. 211 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients.

    Ruosaari, S., Hienonen-Kempas, T., Puustinen, A., Sarhadi, V. K., Hollmén, J., Knuutila, S., Saharinen, J., Wikman, H. & Anttila, S., 2008, In: BMC MED GENOMICS. 1, p. 55

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment.

    Köllermann, J., Weikert, S., Schostak, M., Kempkensteffen, C., Kleinschmidt, K., Rau, T. & Pantel, K., 2008, In: J CLIN ONCOL. 26, 30, p. 4928-4933 30.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Review: Biological relevance of disseminated tumor cells in cancer patients.

    Riethdorf, S., Wikman, H. & Pantel, K., 2008, In: INT J CANCER. 123, 9, p. 1991-2006 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II disease.

    Helms, M. W., Kemming, D., Pospisil, H., Vogt, U., Buerger, H., Korsching, E., Liedtke, C., Schlotter, C. M., Wang, A., Chan, S. Y. & Brandt, B., 2008, In: BRIT J CANCER. 99, 5, p. 774-780 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Translating genetic pathways to protein networks for cancer sub-typing.

    Eltze, E., Schmidt, H., Semjonow, A. & Brandt, B., 2008, In: ANN ONCOL. 19, 5, p. 44-47 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. 2007
  9. A critical evaluation of loss of heterozygosity detected in tumor tissues, blood serum and bone marrow plasma from patients with breast cancer.

    Schwarzenbach, H., Müller, V., Beeger, C., Gottberg, M., Stahmann, N. & Pantel, K., 2007, In: BREAST CANCER RES. 9, 5, p. 66 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Cell cycle regulating proteins p21 and p27 in prognosis of oral squamous cell carcinomas.

    Fillies, T., Woltering, M., Brandt, B., Jean-Paul, V. D., Werkmeister, R., Joos, U. & Buerger, H., 2007, In: ONCOL REP. 17, 2, p. 355-359 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Central mesenteric lymph node BER-Ep4+ cells in colorectal cancer: challenge to sentinel node concept?

    Schurr, P., Behnke, S., Kaifi, J., Bogoevski, D., Link, B-C., Mann, O., Strate, T., Pantel, K., Izbicki, J. R. & Yekebas, E. F., 2007, In: DIGEST SURG. 24, 1, p. 19-27 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Current status in human breast cancer micrometastasis.

    Alix-Panabières, C., Müller, V. & Pantel, K., 2007, In: CURR OPIN ONCOL. 19, 6, p. 558-563 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Cytokeratin alteration in oral leukoplakia and oral squamous cell carcinoma.

    Fillies, T., Jogschies, M., Kleinheinz, J., Brandt, B., Joos, U. & Buerger, H., 2007, In: ONCOL REP. 18, 3, p. 639-643 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Detection and characterization of putative metastatic precursor cells in cancer patients.

    Alix-Panabières, C., Vendrell, J-P., Pellé, O., Rebillard, X., Riethdorf, S., Müller, V., Fabbro, M. & Pantel, K., 2007, In: CLIN CHEM. 53, 3, p. 537-539 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system.

    Riethdorf, S., Fritsche, H., Müller, V., Rau, T., Schindlbeck, C., Rack, B., Janni, W., Coith, C., Beck, K., Jänicke, F., Jackson, S., Gornet, T., Cristofanilli, M. & Pantel, K., 2007, In: CLIN CANCER RES. 13, 3, p. 920-928 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Detection of MAGE-A transcripts in bone marrow is an independent prognostic factor in operable non-small-cell lung cancer.

    Sienel, W., Mecklenburg, I., Dango, S., Ehrhardt, P., Kirschbaum, A., Passlick, B. & Pantel, K., 2007, In: CLIN CANCER RES. 13, 13, p. 3840-3847 13.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Detection of tumor-specific DNA in blood and bone marrow plasma from patients with prostate cancer.

    Schwarzenbach, H., Chun, F., Lange, I., Carpenter, S., Gottberg, M., Erbersdobler, A., Friedrich, M., Huland, H. & Pantel, K., 2007, In: INT J CANCER. 120, 7, p. 1465-1471 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Determination of microvessel density by quantitative real-time PCR in esophageal cancer: correlation with histologic methods, angiogenic growth factor expression, and lymph node metastasis.

    Loges, S., Clausen, H., Reichelt, U., Bubenheim, M., Erbersdobler, A., Schurr, P., Yekebas, E. F., Schuch, G., Izbicki, J. R., Pantel, K., Bokemeyer, C. & Fiedler, W., 2007, In: CLIN CANCER RES. 13, 1, p. 76-80 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Egfr amplification specific gene expression in phyllodes tumours of the breast.

    Agelopoulos, K., Kersting, C., Korsching, E., Schmidt, H., Kuijper, A., August, C., Wülfing, P., Tio, J., Boecker, W., Diest, V., Brandt, B., Brandt, B. & Buerger, H., 2007, In: MOL CELL ONCOL. 29, 6, p. 443-451 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Epidermal growth factor receptor expression in high-grade osteosarcomas is associated with a good clinical outcome.

    Kersting, C., Gebert, C., Agelopoulos, K., Schmidt, H., Diest, V., Paul, J., Juergens, H., Winkelmann, W., Kevric, M., Brandt, B., Brandt, B., Bielack, S. & Buerger, H., 2007, In: CLIN CANCER RES. 13, 10, p. 2998-3005 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Gene expression and copy number profiling suggests the importance of allelic imbalance in 19p in asbestos-associated lung cancer.

    Wikman, H., Ruosaari, S., Nymark, P., Sarhadi, V. K., Saharinen, J., Vanhala, E., Karjalainen, A., Hollmén, J., Knuutila, S. & Anttila, S., 2007, In: ONCOGENE. 26, 32, p. 4730-4737 32.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. L1 is associated with micrometastatic spread and poor outcome in colorectal cancer.

    Kaifi, J., Reichelt, U., Quaas, A., Schurr, P., Wachowiak, R., Yekebas, E. F., Strate, T., Schneider, C. G., Pantel, K., Schachner, M., Sauter, G. & Izbicki, J. R., 2007, In: MODERN PATHOL. 20, 11, p. 1183-1190 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Lymph node micrometastases in lung cancer.

    Harms-Effenberger, K., Sienel, W. & Pantel, K., 2007, In: Cancer Treat Res. 135, p. 167-175

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. [Mapping of a deletion interval on 8p21-22 in prostate cancer by gene dosage PCR]

    Schmidt, H., Semjonow, A., Csiszar, K., Korsching, E., Brandt, B. & Eltze, E., 2007, In: Verh Dtsch Ges Pathol. 91, p. 302-307

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters.

    Wischnewski, F., Friese, O., Pantel, K. & Schwarzenbach, H., 2007, In: MOL CANCER RES. 5, 7, p. 749-759 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Microsatellite analysis in serum DNA as a diagnostic tool for distinction of patients with unknown pancreatic masses.

    Wachowiak, R., Kaifi, J., Schwarzenbach, H., Yekebas, E. F., Merkert, P., Schurr, P., Hansen, B., Reichelt, U., Strate, T., Pantel, K. & Izbicki, J. R., 2007, In: DIAGN MOL PATHOL. 16, 3, p. 174-178 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Network modeling links breast cancer susceptibility and centrosome dysfunction.

    Pujana, M. A., Han, J-D. J., Starita, L. M., Stevens, K. N., Tewari, M., Ahn, J. S., Rennert, G., Moreno, V., Kirchhoff, T., Gold, B., Assmann, V., Elshamy, W. M., Rual, J-F., Levine, D., Rozek, L. S., Gelman, R. S., Gunsalus, K. C., Greenberg, R. A., Sobhian, B., Bertin, N., Venkatesan, K., Ayivi-Guedehoussou, N., Solé, X., Hernández, P., Lázaro, C., Nathanson, K. L., Weber, B. L., Cusick, M. E., Hill, D. E., Offit, K., Livingston, D. M., Gruber, S. B., Parvin, J. D. & Vidal, M., 2007, In: NAT GENET. 39, 11, p. 1338-1349 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Short tandem repeat polymorphism in exon 4 of esophageal cancer-related gene 2 detected in genomic DNA is a prognostic marker for esophageal cancer.

    Kaifi, J., Rawnaq, T., Schurr, P., Yekebas, E. F., Mann, O., Merkert, P., Link, B-C., Kalinin, V., Pantel, K., Sauter, G., Strate, T. & Izbicki, J. R., 2007, In: AM J SURG. 194, 3, p. 380-384 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Similar patterns of loss of heterozygosity in serum of adenocarcinoma of the distal oesophagus and the cardia in early diagnosis.

    Wachowiak, R., Kaifi, J., Schurr, P., Merkert, P., Yekebas, E. F., Schwarzenbach, H., Strate, T., Sauter, G. & Izbicki, J. R., 2007, In: ANTICANCER RES. 27, 1, p. 477-481 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. The clinical significance of circulating tumor cells.

    Pantel, K. & Alix-Panabières, C., 2007, In: NAT CLIN PRACT ONCOL. 4, 2, p. 62-63 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Tumor cell dormancy: an NCI workshop report.

    Vessella, R. L., Pantel, K. & Mohla, S., 2007, In: CANCER BIOL THER. 6, 9, p. 1496-1504 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. 2006
  33. Circulating tumour-associated plasma DNA represents an independent and informative predictor of prostate cancer.

    Chun, F. K-H., Müller, I., Lange, I., Friedrich, M., Erbersdobler, A., Karakiewicz, P. I., Graefen, M., Pantel, K., Huland, H. & Schwarzenbach, H., 2006, In: BJU INT. 98, 3, p. 544-548 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Comparison of genetic alterations detected in circulating microsatellite DNA in blood plasma samples of patients with prostate cancer and benign prostatic hyperplasia.

    Müller, I., Urban, K., Pantel, K. & Schwarzenbach, H., 2006, In: ANN NY ACAD SCI. 1075, p. 222-229

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Expression of CD83 is regulated by HuR via a novel cis-active coding region RNA element.

    Prechtel, A. T., Chemnitz, J., Schirmer, S., Ehlers, C., Langbein-Detsch, I., Stülke, J., Dabauvalle, M-C., Kehlenbach, R. H. & Hauber, J., 2006, In: J BIOL CHEM. 281, 16, p. 10912-10925 16.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. High incidence of EMMPRIN expression in human tumors.

    Riethdorf, S., Reimers, N., Assmann, V., Kornfeld, J-W., Terracciano, L., Sauter, G. & Pantel, K., 2006, In: INT J CANCER. 119, 8, p. 1800-1810 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Prognostic and predictive effects of immunohistochemical factors in high-risk primary breast cancer patients.

    Kröger, N., Milde-Langosch, K., Riethdorf, S., Schmoor, C., Schumacher, M., Zander, A. R. & Löning, T., 2006, In: CLIN CANCER RES. 12, 1, p. 159-168 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells.

    Wischnewski, F., Pantel, K. & Schwarzenbach, H., 2006, In: MOL CANCER RES. 4, 5, p. 339-349 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. 2005
  40. The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence

    Janni, W., Rack, B., Schindlbeck, C., Strobl, B., Rjosk, D., Braun, S., Sommer, H., Pantel, K., Gerber, B. & Friese, K., 01.03.2005, In: CANCER-AM CANCER SOC. 103, 5, p. 884-91 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. A novel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues.

    Ritz, J. M., Kühle, O., Riethdorf, S., Sipos, B., Deppert, W., Englert, C. & Günes, C., 2005, In: CANCER RES. 65, 4, p. 1187-1196 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells.

    Willipinski-Stapelfeldt, B., Riethdorf, S., Assmann, V., Woelfle, U., Rau, T., Sauter, G., Heukeshoven, J. & Pantel, K., 2005, In: CLIN CANCER RES. 11, 22, p. 8006-8014 22.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Circulating tumor cells in breast cancer: correlation to bone marrow micrometastases, heterogeneous response to systemic therapy and low proliferative activity.

    Müller, V., Stahmann, N., Riethdorf, S., Rau, T., Zabel, T., Goetz, A., Jänicke, F. & Pantel, K., 2005, In: CLIN CANCER RES. 11, 10, p. 3678-3685 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Detection of human telomerase RNA in the tumour-surrounding mucosa of bladder carcinomas as a marker for premalignant transformation.

    Leuenroth, S., Riethdorf, S., Erbersdobler, A., Riethdorf, L., Löning, T., Huland, H. & Friedrich, M., 2005, In: BJU INT. 96, 4, p. 553-557 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Pro-sequence and Ca2+-binding: implications for folding and maturation of Ntn-hydrolase penicillin amidase from E. coli.

    Ignatova, Z., Wischnewski, F., Notbohm, H. & Kasche, V., 2005, In: J MOL BIOL. 348, 4, p. 999-1014 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. 2004
  47. Detection and characterization of circulating microsatellite-DNA in blood of patients with breast cancer

    Schwarzenbach, H., Müller, V., Stahmann, N. & Pantel, K., 01.06.2004, In: ANN NY ACAD SCI. 1022, p. 25-32 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Expression of extracellular matrix metalloproteases inducer on micrometastatic and primary mammary carcinoma cells.

    Reimers, N., Zafrakas, K., Assmann, V., Egen, C., Riethdorf, L., Riethdorf, S., Berger, J., Ebel, S., Jänicke, F., Sauter, G. & Pantel, K., 2004, In: CLIN CANCER RES. 10, 10, p. 3422-3428 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. p16INK4A expression as biomarker for HPV 16-related vulvar neoplasias.

    Riethdorf, S., Neffen, E. F., Cviko, A., Löning, T., Crum, C. P. & Riethdorf, L., 2004, In: HUM PATHOL. 35, 12, p. 1477-1483 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Sentinel Lymph Node Dissection and Micrometastasis Detection in Bone Marrow and Lymph Nodes: Molecular Oncology of Breast Cancer

    Müller, V., Kasimir-Bauer, S. & Pantel, K., 2004, Molecular Oncology of Breast Cancer. Ross, J. S. & Hortobagyi, G. (eds.). Jones and Bartlett, p. 117-127 11 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  51. 2003
  52. Comparative evaluation of urokinase-type plasminogen activator receptor expression in primary breast carcinomas and on metastatic tumor cells

    Hemsen, A., Riethdorf, L., Brünner, N., Berger, J., Ebel, S., Thomssen, C., Jänicke, F. & Pantel, K., 20.12.2003, In: INT J CANCER. 107, 6, p. 903-9 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Stimulatory effect of progesterone on the expression of steroidogenic acute regulatory protein in MA-10 Leydig cells

    Schwarzenbach, H., Manna, P. R., Stocco, D. M., Chakrabarti, G. & Mukhopadhyay, A. K., 01.03.2003, In: BIOL REPROD. 68, 3, p. 1054-63 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Clinical Relevance of Micrometastatic Disease in Patients with Solid Tumors

    Muller, V. & Pantel, K., 03.2003, In: AM J CANCER. 2, 2, p. 77-86

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. Clonal expansion and HPV-induced immortalization are early molecular alterations in cervical carcinogenesis.

    Park, T-W., Riethdorf, S., Schulz, G., Riethdorf, L., Wright, T. & Löning, T., 2003, In: ANTICANCER RES. 23, 1, p. 155-160 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. Correlation on serum HER-2/neu extracellular domain levels in metastatic breast cancer with the expression of HER-2/neu determined by immunohistochemistry in primary tumors

    Witzel, I., Thomssen, C., Pantel, K., Neumann, R., Carney, W., Loening, T., Jaenicke, F. & Müller, V., 2003, In: BREAST CANCER RES TR. 82, Suppl. 1, p. S 143

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review