Expression of extracellular matrix metalloproteases inducer on micrometastatic and primary mammary carcinoma cells.

  • Natalie Reimers
  • Kristine Zafrakas
  • Volker Assmann
  • Cornelia Egen
  • Lutz Riethdorf
  • Sabine Riethdorf
  • Jürgen Berger
  • Sebastian Ebel
  • Fritz Jänicke
  • Guido Sauter
  • Klaus Pantel

Related Research units

Abstract

EMMPRIN (extracellular matrix metalloprotease inducer) is a glycosylated member of the immunoglobulin superfamily known to stimulate the production of matrix metalloproteases (MMPs) 1, 2, and 3 and MT1-MMP in peritumoral fibroblasts. We here evaluated whether EMMPRIN expression is related to tumor progression in human breast cancer.

Bibliographical data

Original languageEnglish
Article number10
ISSN1078-0432
Publication statusPublished - 2004
pubmed 15161697