Institute of Synaptic Neuroscience
Publications
- 2024
Functional inhibition of katanin affects synaptic plasticity
Lombino, F. L., Schwarz, J. R., Pechmann, Y., Schweizer, M., Jark, R., Stange, O., Glatzel, M., Gee, C. E., Hausrat, T. J., Gromova, K. V. & Kneussel, M., 27.03.2024, In: J NEUROSCI. 44, 13, e0374232023.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Deep Image Prior for Spatio-temporal Fluorescence Microscopy Images: DECO-DIP
Meyer, L., Woelk, L-M., Gee, C., Lohr, C., Arcot Kannabiran, S., Diercks, B-P. & Werner, R., 2024, Bildverarbeitung für die Medizin 2024: Proceedings, German Conference on Medical Image Computing, Erlangen, March 10–12, 2024. Maier, A., Deserno, TM., Handels, H., Maier-Hein, K., Palm, C. & Tolxdorff, TM. (eds.). 1 ed. Springer Vieweg, p. 322-327 6 p. (Informatik Aktuell).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2023
Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES
Schwarzová, B., Stüdemann, T., Sönmez, M., Rössinger, J., Pan, B., Eschenhagen, T., Stenzig, J., Wiegert, J. S., Christ, T. & Weinberger, F., 12.2023, In: PFLUG ARCH EUR J PHY. 475, 12, p. 1463-1477 15 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sensitive multicolor indicators for monitoring norepinephrine in vivo
Kagiampaki, Z., Rohner, V., Kiss, C., Curreli, S., Dieter, A., Wilhelm, M., Harada, M., Duss, S. N., Dernic, J., Bhat, M. A., Zhou, X., Ravotto, L., Ziebarth, T., Wasielewski, L. M., Sönmez, L., Benke, D., Weber, B., Bohacek, J., Reiner, A., Wiegert, J. S., Fellin, T. & Patriarchi, T., 09.2023, In: NAT METHODS. 20, 9, p. 1426-1436 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal
Grochowska, K. M., Sperveslage, M., Raman, R., Failla, A. V., Głów, D., Schulze, C., Laprell, L., Fehse, B. & Kreutz, M. R., 29.08.2023, In: CELL REP. 42, 8, p. 112998Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The kinesin Kif21b binds myosin Va and mediates changes in actin dynamics underlying homeostatic synaptic downscaling
Gromova, K. V., Thies, E., Janiesch, P. C., Lützenkirchen, F. P., Zhu, Y., Stajano, D., Dürst, C. D., Schweizer, M., Konietzny, A., Mikhaylova, M., Gee, C. E. & Kneussel, M., 25.07.2023, In: CELL REP. 42, 7, p. 1-24 112743.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A bistable inhibitory OptoGPCR for multiplexed optogenetic control of neural circuits
Wietek, J., Nozownik, A., Pulin, M., Saraf-Sinik, I., Matosevich, N., Malan, D., Brown, B. J., Dine, J., Levy, R., Litvin, A., Regev, N., Subramaniam, S., Bitton, E., Benjamin, A., Copits, B. A., Sasse, P., Rost, B. R., Schmitz, D., Soba, P., Nir, Y., Wiegert, J. S. & Yizhar, O., 02.07.2023, In: bioRxiv.Research output: SCORING: Contribution to journal › Preprint › Research
Dissociating instructive from permissive roles of brain circuits with reversible neural activity manipulations
Quintana, D., Bounds, H. A., Brown, J., Wang, M., Bhatla, N., Wiegert, J. S. & Adesnik, H., 12.05.2023, In: bioRxiv.Research output: SCORING: Contribution to journal › Preprint › Research
All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals
Bergs, A. C. F., Liewald, J. F., Rodriguez-Rozada, S., Liu, Q., Wirt, C., Bessel, A., Zeitzschel, N., Durmaz, H., Nozownik, A., Dill, H., Jospin, M., Vierock, J., Bargmann, C. I., Hegemann, P., Wiegert, J. S. & Gottschalk, A., 06.04.2023, In: NAT COMMUN. 14, 1, p. 1939Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A flexible and versatile system for multi-color fiber photometry and optogenetic manipulation
Formozov, A., Dieter, A. & Wiegert, J. S., 27.03.2023, In: CELL REP METHODS. 3, 3, p. 100418Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A2A adenosine receptor-driven cAMP signaling in olfactory bulb astrocytes is unaffected in experimental autoimmune encephalomyelitis
Wendlandt, M., Kürten, A. J., Beiersdorfer, A., Schubert, C., Samad-Yazdtchi, K., Sauer, J., Pinto, M. C., Schulz, K., Friese, M. A., Gee, C. E., Hirnet, D. & Lohr, C., 2023, In: FRONT IMMUNOL. 14, p. 1-10 1273837.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2022
Spike-timing-dependent plasticity rewards synchrony rather than causality
Anisimova, M., van Bommel, B., Wang, R., Mikhaylova, M., Wiegert, J. S., Oertner, T. G. & Gee, C. E., 15.12.2022, In: CEREB CORTEX. 33, 1, p. 23-34 12 p., bhac050.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
ΔFosB accumulation in hippocampal granule cells drives cFos pattern separation during spatial learning
Lamothe-Molina, P. J., Franzelin, A., Beck, L., Li, D., Auksutat, L., Fieblinger, T., Laprell, L., Alhbeck, J., Gee, C. E., Kneussel, M., Engel, A. K., Hilgetag, C. C., Morellini, F. & Oertner, T. G., 26.10.2022, In: NAT COMMUN. 13, 1, 6376.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vesicular release probability sets the strength of individual Schaffer collateral synapses
Dürst, C. D., Wiegert, J. S., Schulze, C., Helassa, N., Török, K. & Oertner, T. G., 17.10.2022, In: NAT COMMUN. 13, 1, 6126.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Presynaptic cGMP sets synaptic strength in the striatum and is important for motor learning
Fieblinger, T., Perez-Alvarez, A., Lamothe-Molina, P. J., Gee, C. E. & Oertner, T. G., 03.08.2022, In: EMBO REP. 23, 8, e54361.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing
Rodriguez-Rozada, S., Wietek, J., Tenedini, F., Sauter, K., Dhiman, N., Hegemann, P., Soba, P. & Wiegert, J. S., 09.07.2022, In: COMMUN BIOL. 5, 1, 687.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Visual function restoration with a highly sensitive and fast Channelrhodopsin in blind mice
Chen, F., Duan, X., Yu, Y., Yang, S., Chen, Y., Gee, C. E., Nagel, G., Zhang, K., Gao, S. & Shen, Y., 18.04.2022, In: SIGNAL TRANSDUCT TAR. 7, 1, 104.Research output: SCORING: Contribution to journal › Letter › Research › peer-review
A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis
Fearey, B. C., Binkle, L., Mensching, D., Schulze, C., Lohr, C., Friese, M. A., Oertner, T. G. & Gee, C. E., 09.04.2022, In: SCI REP-UK. 12, 1, 6000.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selective optogenetic control of Gq signaling using human Neuropsin
Wagdi, A., Malan, D., Sathyanarayanan, U., Beauchamp, J. S., Vogt, M., Zipf, D., Beiert, T., Mansuroglu, B., Dusend, V., Meininghaus, M., Schneider, L., Kalthof, B., Wiegert, J. S., König, G. M., Kostenis, E., Patejdl, R., Sasse, P. & Bruegmann, T., 01.04.2022, In: NAT COMMUN. 13, 1, 1765.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Calcium imaging and electrophysiology of hippocampal activity under anesthesia and natural sleep in mice
Formozov, A., Chini, M., Dieter, A., Yang, W., Pöpplau, J. A., Hanganu-Opatz, I. L. & Wiegert, J. S., 29.03.2022, In: SCI DATA. 9, 1, p. 1-11 113.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Temporally extended and reversible neuronal silencing with Aion
Rodriguez-Rozada, S., Wietek, J., Tenedini, F. M., Sauter, K., Hegemann, P., Soba, P. & Wiegert, J. S., 28.02.2022, bioRxivResearch output: Other contribution › Other › Research
Orthogonally-polarized excitation for improved two-photon and second-harmonic-generation microscopy, applied to neurotransmitter imaging with GPCR-based sensors
Pulin, M., Stockhausen, K. E., Masseck, O. A., Kubitschke, M., Busse, B., Wiegert, J. S. & Oertner, T. G., 01.02.2022, In: BIOMED OPT EXPRESS. 13, 2, p. 777-790 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Targeting Noradrenergic Neurons of the Locus Coeruleus: A Comparison of Model Systems and Strategies
Wissing, C., Maheu, M., Wiegert, S. & Dieter, A., 23.01.2022, bioRxivResearch output: Other contribution › Other › Research
A flexible and versatile system for multicolor fiber photometry and optogenetic manipulation
Formozov, A., Dieter, A. & Wiegert, J. S., 01.01.2022, In: bioRxiv. p. 1-48 2022.03.16.484590.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research
Influence of X-rays and gamma-rays on the mechanical performance of human bone factoring out intraindividual bone structure and composition indices
Schmidt, F. N., Hahn, M., Stockhausen, K. E., Rolvien, T., Schmidt, C., Knopp, T., Schulze, C., Püschel, K., Amling, M. & Busse, B., 01.2022, In: MATER TODAY BIO. 13, 100169.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Imaging Synaptic Glutamate Release with Two-Photon Microscopy in Organotypic Slice Cultures
Dürst, C. D. & Oertner, T. G., 2022, Synaptic Vesicles: Methods and Protocols. Dahlmanns, J. & Dahlmanns, M. (eds.). 1 ed. New York, NY: HUMANA PRESS INC, Vol. 2417. p. 205-219 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2021
Contractile force of transplanted cardiomyocytes contributes to heart function after injury
Stüdemann, T., Rössinger, J., Manthey, C., Geertz, B., Srikantharajah, R., Bibra, C. V., Shibamiya, A., Köhne, M., Wiehler, A., Wiegert, J. S., Eschenhagen, T. & Weinberger, F., 23.11.2021, bioRxivResearch output: Other contribution › Other › Research
Time-Dependent Image Restoration of Low-SNR Live-Cell Ca2+ Fluorescence Microscopy Data
Woelk, L-M., Kannabiran, S. A., Brock, V. J., Gee, C. E., Lohr, C., Guse, A. H., Diercks, B-P. & Werner, R., 30.10.2021, In: INT J MOL SCI. 22, 17 p., 11792.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
PACmn for improved optogenetic control of intracellular cAMP
Yang, S., Constantin, O. M., Sachidanandan, D., Hofmann, H., Kunz, T. C., Kozjak-Pavlovic, V., Oertner, T. G., Nagel, G., Kittel, R. J., Gee, C. E. & Gao, S., 18.10.2021, In: BMC BIOL. 19, 1, 227.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Linking emotional valence and anxiety in a mouse insula-amygdala circuit
Nicolas, C., Ju, A., Wu, Y., Eldirdiri, H., Delcasso, S., Jacky, D., Supiot, L., Fornari, C., Vérité, A., Masson, M., Rodriguez-Rozada, S., Wiegert, JS. & Beyeler, A., 10.2021Research output: Other contribution › Other › Research
BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons
Vierock, J., Rodriguez-Rozada, S., Dieter, A., Pieper, F., Sims, R., Tenedini, F., Bergs, A. C. F., Bendifallah, I., Zhou, F., Zeitzschel, N., Ahlbeck, J., Augustin, S., Sauter, K., Papagiakoumou, E., Gottschalk, A., Soba, P., Emiliani, V., Engel, A. K., Hegemann, P. & Wiegert, J. S., 26.07.2021, In: NAT COMMUN. 12, 1, p. 4527Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia
Benitez, D. P., Jiang, S., Wood, J., Wang, R., Hall, C. M., Peerboom, C., Wong, N., Stringer, K. M., Vitanova, K. S., Smith, V. C., Joshi, D., Saito, T., Saido, T. C., Hardy, J., Hanrieder, J., De Strooper, B., Salih, D. A., Tripathi, T., Edwards, F. A. & Cummings, D. M., 15.07.2021, In: MOL NEURODEGENER. 16, 1, 47.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation
Yang, W., Chini, M., Pöpplau, J. A., Formozov, A., Dieter, A., Piechocinski, P., Rais, C., Morellini, F., Sporns, O., Hanganu-Opatz, I. L. & Wiegert, J. S., 01.04.2021, In: PLOS BIOL. 19, 4, p. e3001146Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Photoactivatable CaMKII: Rewiring the Brain, One Synapse at a Time
Gee, C. E. & Oertner, T. G., 04.2021, In: TRENDS NEUROSCI. 44, 4, p. 246-247 2 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Freeze-Frame Imaging of Dendritic Calcium Signals With TubuTag
Perez-Alvarez, A., Huhn, F., Dürst, C. D., Franzelin, A., Lamothe-Molina, P. J. & Oertner, T. G., 04.03.2021, In: FRONT MOL NEUROSCI. 14, p. 635820 635820.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Correction to: The role of microglia membrane potentialin chemotaxis
Laprell, L., Schulze, C., Brehme, M-L. & Oertner, T. G., 28.01.2021, In: J NEUROINFLAMM. 18, 1, p. 33Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
The role of microglia membrane potential in chemotaxis
Laprell, L., Schulze, C., Brehme, M-L. & Oertner, T. G., 10.01.2021, In: J NEUROINFLAMM. 18, 1, 21.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Autophagy, 01.2021, In: AUTOPHAGY. 17, 1, p. 1-382 382 p.Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research
Striatal Control of Movement: A Role for New Neuronal (Sub-) Populations?
Fieblinger, T., 2021, In: FRONT HUM NEUROSCI. 15, 697284.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
Using Genetically Encoded Calcium Indicators to Study Astrocyte Physiology: A Field Guide
Lohr, C., Beiersdorfer, A., Fischer, T., Hirnet, D., Rotermund, N., Sauer, J., Schulz, K. & Gee, C. E., 2021, In: FRONT CELL NEUROSCI. 15, 690147.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
- 2020
Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma
Westermann, L. M., Fleischhauer, L., Vogel, J., Jenei-Lanzl, Z., Floriano Ludwig, N., Schau, L., Morellini, F., Baranowsky, A., Yorgan, T. A., Di Lorenzo, G., Schweizer, M., de Souza Pinheiro, B., Guarany, N. R., Sperb-Ludwig, F., Visioli, F., Oliveira Silva, T., Soul, J., Hendrickx, G., Wiegert, J. S., Schwartz, I. V. D., Clausen-Schaumann, H., Zaucke, F., Schinke, T., Pohl, S. & Danyukova, T., 18.11.2020, In: DIS MODEL MECH. 13, 11Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The vesicular release probability sets the strength of individual Schaffer collateral synapses
Dürst, C., Wiegert, J. S., Schulze, C., Helassa, N., Torok, K. & Oertner, T., 14.10.2020, bioRxiv : Cold Spring Harbor Laboratory Press.Research output: Other contribution › Other › Research
Endoplasmic reticulum visits highly active spines and prevents runaway potentiation of synapses
Perez-Alvarez, A., Yin, S., Schulze, C., Hammer, J. A., Wagner, W. & Oertner, T. G., 08.10.2020, In: NAT COMMUN. 11, 1, p. 5083Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
cFos ensembles in the dentate gyrus rapidly segregate over time and do not form a stable map of space
Lamothe-Molina, P. J., Franzelin, A., Auksutat, L., Laprell, L., Ahlbeck, J., Kneussel, M., Engel, A. K., Morellini, F. & Oertner, T. G., 31.08.2020, US Staat New York : Cold Spring Harbor Laboratory Press.Research output: Other contribution › Other › Research
Freeze-frame imaging of synaptic activity using SynTagMA
Perez-Alvarez, A., Fearey, B. C., O'Toole, R. J., Yang, W., Arganda-Carreras, I., Lamothe-Molina, P. J., Moeyaert, B., Mohr, M. A., Panzera, L. C., Schulze, C., Schreiter, E. R., Wiegert, J. S., Gee, C. E., Hoppa, M. B. & Oertner, T. G., 18.05.2020, In: NAT COMMUN. 11, 1, p. 2464Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Dopamine Receptor Activation Modulates the Integrity of the Perisynaptic Extracellular Matrix at Excitatory Synapses
Mitlöhner, J., Kaushik, R., Niekisch, H., Blondiaux, A., Gee, C. E., Happel, M. F. K., Gundelfinger, E., Dityatev, A., Frischknecht, R. & Seidenbecher, C., 21.01.2020, In: CELLS-BASEL. 9, 2Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2019
Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina
Hüll, K., Benster, T., Manookin, M. B., Trauner, D., Van Gelder, R. N. & Laprell, L., 19.09.2019, In: SCI REP-UK. 9, 1, p. 13561Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monosynaptic hippocampal-prefrontal projections contribute to spatial memory consolidation in mice
Binder, S., Mölle, M., Lippert, M., Bruder, R., Aksamaz, S., Ohl, F., Wiegert, J. S. & Marshall, L., 28.08.2019, In: J NEUROSCI. 39, 35, p. 6978-6991 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Myosin V regulates synaptopodin clustering and localization in the dendrites of hippocampal neurons
Konietzny, A., González-Gallego, J., Bär, J., Perez-Alvarez, A., Drakew, A., Demmers, J. A. A., Dekkers, D. H. W., Hammer, J. A., Frotscher, M., Oertner, T. G., Wagner, W., Kneussel, M. & Mikhaylova, M., 22.08.2019, In: J CELL SCI. 132, 16Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
Oppermann, J., Fischer, P., Silapetere, A., Liepe, B., Rodriguez-Rozada, S., Flores-Uribe, J., Peter, E., Keidel, A., Vierock, J., Kaufmann, J., Broser, M., Luck, M., Bartl, F., Hildebrandt, P., Wiegert, J. S., Béjà, O., Hegemann, P. & Wietek, J., 25.07.2019, In: NAT COMMUN. 10, 1, p. 3315Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review