Using Genetically Encoded Calcium Indicators to Study Astrocyte Physiology: A Field Guide
Related Research units
Abstract
Ca2+ imaging is the most frequently used technique to study glial cell physiology. While chemical Ca2+ indicators served to visualize and measure changes in glial cell cytosolic Ca2+ concentration for several decades, genetically encoded Ca2+ indicators (GECIs) have become state of the art in recent years. Great improvements have been made since the development of the first GECI and a large number of GECIs with different physical properties exist, rendering it difficult to select the optimal Ca2+ indicator. This review discusses some of the most frequently used GECIs and their suitability for glial cell research.
Bibliographical data
Original language | English |
---|---|
Article number | 690147 |
ISSN | 1662-5102 |
DOIs | |
Publication status | Published - 2021 |
Comment Deanary
SFB 1328; FOR 2419
PubMed | 34177468 |
---|