Department of Osteology and Biomechanics

Publications

  1. 2011
  2. Elevated Fra-1 expression causes severe lipodystrophy

    Luther, J., Driessler, F., Megges, M., Hess, A., Herbort, B., Mandic, V., Zaiss, M. M., Reichardt, A., Zech, C., Tuckermann, J. P., Calkhoven, C. F., Wagner, E. F., Schett, G. & David, J-P., 01.05.2011, In: J CELL SCI. 124, Pt 9, p. 1465-76 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Measurement of TLR-Induced Macrophage Spreading by Automated Image Analysis: Differential Role of Myd88 and MAPK in Early and Late Responses

    Wenzel, J., Held, C., Palmisano, R., Teufel, S., David, J-P., Wittenberg, T. & Lang, R., 01.01.2011, In: FRONT PHYSIOL. 2, p. 71

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Articulating spacers used in two-stage revision of infected hip and knee prostheses abrade with time.

    Fink, B., Rechtenbach, A., Büchner, H., Vogt, S. & Hahn, M., 2011, In: CLIN ORTHOP RELAT R. 469, 4, p. 1095-1102 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Biomechanical evaluation for mechanisms of periprosthetic femoral fractures.

    Rupprecht, M., Sellenschloh, K., Großterlinden, L. G., Püschel, K., Morlock, M., Amling, M., Rueger, J. M. & Lehmann, W., 2011, In: J TRAUMA. 70, 4, p. 62-66 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Control of bone formation by the serpentine receptor Frizzled-9.

    Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

    Abdallah, B. M., Ditzel, N., Mahmood, A., Isa, A., Traustadottir, G. A., Schilling, A. F., Ruiz-Hidalgo, M-J., Laborda, J., Amling, M. & Kassem, M., 2011, In: J BONE MINER RES. 26, 7, p. 1457-1471 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Effects of increased bone formation on fracture healing in mice.

    Beil, F. T., Barvencik, F., Gebauer, M., Beil, B., Pogoda, P., Rueger, J. M., Ignatius, A., Schinke, T. & Amling, M., 2011, In: J TRAUMA. 70, 4, p. 857-862 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Fracture prevention by femoroplasty--cement augmentation of the proximal femur.

    Beckmann, J., Springorum, R., Vettorazzi, E., Bachmeier, S., Lüring, C., Tingart, M., Püschel, K., Stark, O. A., Grifka, J., Gehrke, T., Amling, M. & Gebauer, M., 2011, In: J ORTHOP RES. 29, 11, p. 1753-1758 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene.

    Mentrup, B., Marschall, C., Barvencik, F., Amling, M., Plendl, H., Jakob, F. & Beck, C., 2011, In: BONE. 48, 6, p. 1401-1408 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. How much vitamin D do we need for skeletal health?

    von Domarus, C., Brown, J., Barvencik, F., Amling, M. & Pogoda, P., 2011, In: CLIN ORTHOP RELAT R. 469, 11, p. 3127-3133 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells.

    Schulze, J., Bickert, T., Beil, F. T., Zaiss, M. M., Albers, J., Wintges, K., Streichert, T., Klätschke, K., Keller, J., Hissnauer, T-N., Spiro, A. S., Gessner, A., Schett, G., Amling, M., McKenzie, A. N. J., Horst, A. & Schinke, T., 2011, In: J BONE MINER RES. 26, 4, p. 704-717 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Knochen-Implantat-Interface nach 5 Monaten bei einer zementfrei fixierten Sprunggelenksendoprothese (Zenith)

    Jerosch, J., Neuhäuser, C., Zustin, J. & Hahn, M., 2011, In: ORTHOP PRAX. 46, 11, p. 535-538 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Metaphyseal fracture healing follows similar biomechanical rules as diaphyseal healing.

    Claes, L., Reusch, M., Göckelmann, M., Ohnmacht, M., Wehner, T., Amling, M., Beil, F. T. & Ignatius, A., 2011, In: J ORTHOP RES. 29, 3, p. 425-432 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Midkine-deficiency increases the anabolic response of cortical bone to mechanical loading.

    Liedert, A., Mattausch, L., Röntgen, V., Blakytny, R., Vogele, D., Pahl, M., Bindl, R., Neunaber, C., Schinke, T., Harroch, S., Amling, M. & Ignatius, A., 2011, In: BONE. 48, 4, p. 945-951 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Proliferation of the synovial lining cell layer in suggested metal hypersensitivity.

    Burkandt, A., Katzer, A., Thaler, K., Volker, V. B., Friedrich, R., Rüther, W., Amling, M. & Zustin, J., 2011, In: IN VIVO. 25, 4, p. 679-686 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Sex differences in the morphological failure patterns following hip resurfacing arthroplasty.

    Hinsch, A., Vettorazzi, E., Morlock, M. M., Rüther, W., Amling, M. & Zustin, J., 2011, In: BMC MED. 9, p. 113

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo.

    Prawitt, J., Beil, F. T., Marshall, R-P., Bartelt, A., Rüther, W., Heeren, J., Amling, M., Staels, B. & Niemeier, A., 2011, In: BONE. 48, 2, p. 339-346 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Size dependent induction of proinflammatory cytokines and cytotoxicity of particulate beta-tricalciumphosphate in vitro.

    Lange, T., Schilling, A., Peters, F., Mujas, J., Wicklein, D. & Amling, M., 2011, In: BIOMATERIALS. 32, 17, p. 4067-4075 17.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Skeletal mineralization defects in adult hypophosphatasia-a clinical and histological analysis.

    Barvencik, F., Beil, F. T., Gebauer, M., Busse, B., Köhne, T., Seitz, S., Zustin, J., Pogoda, P., Schinke, T. & Amling, M., 2011, In: OSTEOPOROSIS INT. 22, 10, p. 2667-2675 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.

    Saeed, H., Abdallah, B. M., Ditzel, N., Catalá-Lehnen, P., Qiu, W., Amling, M. & Kassem, M., 2011, In: J BONE MINER RES. 26, 7, p. 1494-1505 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. The distal radius, the most frequent fracture localization in humans: a histomorphometric analysis of the microarchitecture of 60 human distal radii and its changes in aging.

    Beil, F. T., Barvencik, F., Gebauer, M., Mumme, M., Beil, B., Pogoda, P., Rueger, J. M., Püschel, K. & Amling, M., 2011, In: J TRAUMA. 70, 1, p. 154-158 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Trabecular reorganization in consecutive iliac crest biopsies when switching from bisphosphonate to strontium ranelate treatment.

    Jobke, B., Burghardt, A. J., Muche, B., Hahn, M., Semler, J., Amling, M., Majumdar, S. & Busse, B., 2011, In: PLOS ONE. 6, 8, p. 23638 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. 2010
  25. Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity.

    Bartelt, A., Beil, F. T., Schinke, T., Röser, K., Ruether, W., Heeren, J. & Niemeier, A., 01.10.2010, In: BONE. 47, 4, p. 736-745 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.

    Zustin, J., Akpalo, H., Gambarotti, M., Priemel, M., Rueger, J. M., Lübke, A., Reske, D., Lange, C., Püschel, K., Lohmann, C., Rüther, W., Amling, M. & Alberghini, M., 01.09.2010, In: AM J PATHOL. 177, 3, p. 1072-1078 7 p., 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation

    Zaiss, M. M., Sarter, K., Hess, A., Engelke, K., Böhm, C., Nimmerjahn, F., Voll, R., Schett, G. & David, J-P., 01.08.2010, In: ARTHRITIS RHEUMATOL. 62, 8, p. 2328-38 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway

    Krönke, G., Uderhardt, S., Kim, K-A., Stock, M., Scholtysek, C., Zaiss, M. M., Surmann-Schmitt, C., Luther, J., Katzenbeisser, J., David, J-P., Abdollahi-Roodsaz, S., Tran, K., Bright, J. M., Binnerts, M. E., Akhmetshina, A., Böhm, C., Distler, J. H., Joosten, L. A. B., Schett, G. & Abo, A., 01.08.2010, In: ARTHRITIS RHEUMATOL. 62, 8, p. 2303-12 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Regulatory T cells protect from local and systemic bone destruction in arthritis

    Zaiss, M. M., Frey, B., Hess, A., Zwerina, J., Luther, J., Nimmerjahn, F., Engelke, K., Kollias, G., Hünig, T., Schett, G. & David, J-P., 15.06.2010, In: J IMMUNOL. 184, 12, p. 7238-46 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints

    Uderhardt, S., Diarra, D., Katzenbeisser, J., David, J-P., Zwerina, J., Richards, W., Kronke, G. & Schett, G., 01.03.2010, In: ANN RHEUM DIS. 69, 3, p. 592-7 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones

    Maes, C., Goossens, S., Bartunkova, S., Drogat, B., Coenegrachts, L., Stockmans, I., Moermans, K., Nyabi, O., Haigh, K., Naessens, M., Haenebalcke, L., Tuckermann, J. P., Tjwa, M., Carmeliet, P., Mandic, V., David, J-P., Behrens, A., Nagy, A., Carmeliet, G. & Haigh, J. J., 20.01.2010, In: EMBO J. 29, 2, p. 424-41 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Biomechanical evaluation of peri- and interprosthetic fractures of the femur.

    Lehmann, W., Rupprecht, M., Hellmers, N., Sellenschloh, K., Briem, D., Püschel, K., Amling, M., Morlock, M. & Rueger, J. M., 2010, In: J TRAUMA. 68, 6, p. 1459-1463 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone.

    Busse, B., Djonic, D., Milovanovic, P., Hahn, M., Püschel, K., Ritchie, R. O., Djuric, M. & Amling, M., 2010, In: AGING CELL. 9, 6, p. 1065-1075 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Die Moorleiche aus dem Mittelalter war Rechtshänder.

    Barvencik, F., Pestka, J-M., Beil, F. T., Marshall, R-P., Fansa, M., Amling, M. & Püschel, K., 2010, Das Kind aus der Esterweger Dose: Dokumentation einer außergewöhnlichen Skelett-Moorleiche. Isensee-Verlag, p. 63-68 6 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  35. Effects of estrogen on fracture healing in mice.

    Beil, F. T., Barvencik, F., Gebauer, M., Seitz, S., Rueger, J. M., Ignatius, A., Pogoda, P., Schinke, T. & Amling, M., 2010, In: J TRAUMA. 69, 5, p. 1259-1265 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.

    Bozec, A., Bakiri, L., Jimenez, M., Schinke, T., Amling, M. & Wagner, E. F., 2010, In: J CELL BIOL. 190, 6, p. 1093-1106 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.

    Rauch, A., Seitz, S., Baschant, U., Schilling, A., Illing, A., Stride, B., Kirilov, M., Mandic, V., Takacz, A., Schmidt-Ullrich, R., Ostermay, S., Schinke, T., Spanbroek, R., Zaiss, M. M., Angel, P. E., Lerner, U. H., David, J-P., Reichardt, H. M., Amling, M., Schütz, G. & Tuckermann, J. P., 2010, In: CELL METAB. 11, 6, p. 517-531 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1.

    Seitz, S., Schnabel, C., Busse, B., Schmidt, H., Beil, F. T., Friedrich, R., Schinke, T., Mautner, V. F. & Amling, M., 2010, In: OSTEOPOROSIS INT. 21, 1, p. 119-127 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Identification of molecular markers for articular cartilage.

    Hissnauer, T. N., Baranowsky, A., Pestka, J-M., Streichert, T., Wiegandt, K., Goepfert, C., Beil, F. T., Albers, J., Schulze, J., Ueblacker, P., Petersen, J. P., Schinke, T., Meenen, N., Pörtner, R. & Amling, M., 2010, In: OSTEOARTHR CARTILAGE. 18, 12, p. 1630-1638 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Increased trabecular bone formation in mice lacking the growth factor midkine.

    Neunaber, C., Catalá-Lehnen, P., Beil, F. T., Marshall, R-P., Kanbach, V., Baranowsky, A., Lehmann, W., Streichert, T., Ignatius, A., Muramatsu, T., Schinke, T. & Amling, M., 2010, In: J BONE MINER RES. 25, 8, p. 1724-1735 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.

    Schulze, J., Seitz, S., Saito, H., Schneebauer, M., Marshall, R-P., Baranowsky, A., Busse, B., Schilling, A., Friedrich, F., Albers, J., Spiro, A. S., Zustin, J., Streichert, T., Ellwanger, K., Niehrs, C., Amling, M., Baron, R. & Schinke, T., 2010, In: PLOS ONE. 5, 4, p. 10309 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Novel complexities regarding BMPs and fracture healing.

    Schinke, T. & Amling, M., 2010, In: J BONE MINER RES. 25, 6, p. 1193-1195 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Osteologische Untersuchungen einer Moorleiche aus dem Mittelalter.

    Pestka, J-M., Barvencik, F., Beil, F. T., Marshall, R-P., Fansa, M., Amling, M. & Püschel, K., 2010, Das Kind aus der Esterweger Dose: Dokumentation einer außergewöhnlichen Skelett-Moorleiche. Isensee-Verlag, p. 57-62 6 p.

    Research output: SCORING: Contribution to book/anthologySCORING: Contribution to collected editions/anthologiesResearchpeer-review

  44. Preproenkephalin (Penk) is expressed in differentiated osteoblasts, and its deletion in Hyp mice partially rescues their bone mineralization defect.

    Seitz, S., Barvencik, F., Gebauer, M., Albers, J., Schulze, J., Streichert, T., Amling, M. & Schinke, T., 2010, In: CALCIFIED TISSUE INT. 86, 4, p. 282-293 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Region-specific sex-dependent pattern of age-related changes of proximal femoral cancellous bone and its implications on differential bone fragility.

    Djuric, M., Djonic, D., Milovanovic, P., Nikolic, S., Marshall, R-P., Marinkovic, J. & Hahn, M., 2010, In: CALCIFIED TISSUE INT. 86, 3, p. 192-201 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Reorganization of the femoral cortex due to age-, sex-, and endoprosthetic-related effects emphasized by osteonal dimensions and remodeling.

    Busse, B., Hahn, M., Schinke, T., Püschel, K., Duda, G. N. & Amling, M., 2010, In: J BIOMED MATER RES A. 92, 4, p. 1440-1451 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Skeletal analysis and comparison of bog bodies from Northern European peat bogs.

    Pestka, J-M., Barvencik, F., Beil, F. T., Marshall, R-P., Jopp, E., Schilling, A., Bauerochse, A., Fansa, M., Püschel, K. & Amling, M., 2010, In: SCI NAT-HEIDELBERG. 97, 4, p. 393-402 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Synchrotron-microcomputed tomography studies of normal and pathological cranial sutures: further insight.

    Regelsberger, J., Schmidt, T., Busse, B., Herzen, J., Tsokos, M., Amling, M. & Beckmann, F., 2010, In: J NEUROSURG-PEDIATR. 5, 3, p. 238-242 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation.

    Maronde, E., Schilling, A., Seitz, S., Schinke, T., Schmutz, I., van der Horst, G., Amling, M. & Albrecht, U., 2010, In: PLOS ONE. 5, 7, p. 11527 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. 2009
  51. The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss

    Böhm, C., Hayer, S., Kilian, A., Zaiss, M. M., Finger, S., Hess, A., Engelke, K., Kollias, G., Krönke, G., Zwerina, J., Schett, G. & David, J-P., 01.11.2009, In: J IMMUNOL. 183, 9, p. 5938-47 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Osteoidosteom. Minimal-invasive, bildwandlergesteuerte Resektion und histopathologische Diagnosesicherung mittels Diamanthohlfräsen

    Spiro, A. S., Zustin, J., Habermann, C., Meenen, N., Sauter, G., Amling, M., Rueger, J. M. & Priemel, M., 01.10.2009, In: ORTHOPADE. 38, 10, p. 962-969 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Mesenchymale Stammzellen bei Arthritis

    David, J-P., Zwerina, J. & Schett, G., 01.05.2009, In: Z RHEUMATOL. 68, 3, p. 228-33 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearch