Department of Osteology and Biomechanics
Publications
- 2011
Elevated Fra-1 expression causes severe lipodystrophy
Luther, J., Driessler, F., Megges, M., Hess, A., Herbort, B., Mandic, V., Zaiss, M. M., Reichardt, A., Zech, C., Tuckermann, J. P., Calkhoven, C. F., Wagner, E. F., Schett, G. & David, J-P., 01.05.2011, In: J CELL SCI. 124, Pt 9, p. 1465-76 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Measurement of TLR-Induced Macrophage Spreading by Automated Image Analysis: Differential Role of Myd88 and MAPK in Early and Late Responses
Wenzel, J., Held, C., Palmisano, R., Teufel, S., David, J-P., Wittenberg, T. & Lang, R., 01.01.2011, In: FRONT PHYSIOL. 2, p. 71Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Articulating spacers used in two-stage revision of infected hip and knee prostheses abrade with time.
Fink, B., Rechtenbach, A., Büchner, H., Vogt, S. & Hahn, M., 2011, In: CLIN ORTHOP RELAT R. 469, 4, p. 1095-1102 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biomechanical evaluation for mechanisms of periprosthetic femoral fractures.
Rupprecht, M., Sellenschloh, K., Großterlinden, L. G., Püschel, K., Morlock, M., Amling, M., Rueger, J. M. & Lehmann, W., 2011, In: J TRAUMA. 70, 4, p. 62-66 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Control of bone formation by the serpentine receptor Frizzled-9.
Albers, J., Schulze, J., Beil, F. T., Gebauer, M., Baranowsky, A., Keller, J., Marshall, R-P., Wintges, K., Friedrich, F., Priemel, M., Schilling, A., Rueger, J. M., Cornils, K., Fehse, B., Streichert, T., Sauter, G., Jakob, F., Insogna, K. L., Pober, B., Knobeloch, K-P., Francke, U., Amling, M. & Schinke, T., 2011, In: J CELL BIOL. 192, 6, p. 1057-1072 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Abdallah, B. M., Ditzel, N., Mahmood, A., Isa, A., Traustadottir, G. A., Schilling, A. F., Ruiz-Hidalgo, M-J., Laborda, J., Amling, M. & Kassem, M., 2011, In: J BONE MINER RES. 26, 7, p. 1457-1471 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effects of increased bone formation on fracture healing in mice.
Beil, F. T., Barvencik, F., Gebauer, M., Beil, B., Pogoda, P., Rueger, J. M., Ignatius, A., Schinke, T. & Amling, M., 2011, In: J TRAUMA. 70, 4, p. 857-862 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fracture prevention by femoroplasty--cement augmentation of the proximal femur.
Beckmann, J., Springorum, R., Vettorazzi, E., Bachmeier, S., Lüring, C., Tingart, M., Püschel, K., Stark, O. A., Grifka, J., Gehrke, T., Amling, M. & Gebauer, M., 2011, In: J ORTHOP RES. 29, 11, p. 1753-1758 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Functional characterization of a novel mutation localized in the start codon of the tissue-nonspecific alkaline phosphatase gene.
Mentrup, B., Marschall, C., Barvencik, F., Amling, M., Plendl, H., Jakob, F. & Beck, C., 2011, In: BONE. 48, 6, p. 1401-1408 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
How much vitamin D do we need for skeletal health?
von Domarus, C., Brown, J., Barvencik, F., Amling, M. & Pogoda, P., 2011, In: CLIN ORTHOP RELAT R. 469, 11, p. 3127-3133 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells.
Schulze, J., Bickert, T., Beil, F. T., Zaiss, M. M., Albers, J., Wintges, K., Streichert, T., Klätschke, K., Keller, J., Hissnauer, T-N., Spiro, A. S., Gessner, A., Schett, G., Amling, M., McKenzie, A. N. J., Horst, A. & Schinke, T., 2011, In: J BONE MINER RES. 26, 4, p. 704-717 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Knochen-Implantat-Interface nach 5 Monaten bei einer zementfrei fixierten Sprunggelenksendoprothese (Zenith)
Jerosch, J., Neuhäuser, C., Zustin, J. & Hahn, M., 2011, In: ORTHOP PRAX. 46, 11, p. 535-538 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Metaphyseal fracture healing follows similar biomechanical rules as diaphyseal healing.
Claes, L., Reusch, M., Göckelmann, M., Ohnmacht, M., Wehner, T., Amling, M., Beil, F. T. & Ignatius, A., 2011, In: J ORTHOP RES. 29, 3, p. 425-432 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Midkine-deficiency increases the anabolic response of cortical bone to mechanical loading.
Liedert, A., Mattausch, L., Röntgen, V., Blakytny, R., Vogele, D., Pahl, M., Bindl, R., Neunaber, C., Schinke, T., Harroch, S., Amling, M. & Ignatius, A., 2011, In: BONE. 48, 4, p. 945-951 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Proliferation of the synovial lining cell layer in suggested metal hypersensitivity.
Burkandt, A., Katzer, A., Thaler, K., Volker, V. B., Friedrich, R., Rüther, W., Amling, M. & Zustin, J., 2011, In: IN VIVO. 25, 4, p. 679-686 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Sex differences in the morphological failure patterns following hip resurfacing arthroplasty.
Hinsch, A., Vettorazzi, E., Morlock, M. M., Rüther, W., Amling, M. & Zustin, J., 2011, In: BMC MED. 9, p. 113Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo.
Prawitt, J., Beil, F. T., Marshall, R-P., Bartelt, A., Rüther, W., Heeren, J., Amling, M., Staels, B. & Niemeier, A., 2011, In: BONE. 48, 2, p. 339-346 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Size dependent induction of proinflammatory cytokines and cytotoxicity of particulate beta-tricalciumphosphate in vitro.
Lange, T., Schilling, A., Peters, F., Mujas, J., Wicklein, D. & Amling, M., 2011, In: BIOMATERIALS. 32, 17, p. 4067-4075 17.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Skeletal mineralization defects in adult hypophosphatasia-a clinical and histological analysis.
Barvencik, F., Beil, F. T., Gebauer, M., Busse, B., Köhne, T., Seitz, S., Zustin, J., Pogoda, P., Schinke, T. & Amling, M., 2011, In: OSTEOPOROSIS INT. 22, 10, p. 2667-2675 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.
Saeed, H., Abdallah, B. M., Ditzel, N., Catalá-Lehnen, P., Qiu, W., Amling, M. & Kassem, M., 2011, In: J BONE MINER RES. 26, 7, p. 1494-1505 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The distal radius, the most frequent fracture localization in humans: a histomorphometric analysis of the microarchitecture of 60 human distal radii and its changes in aging.
Beil, F. T., Barvencik, F., Gebauer, M., Mumme, M., Beil, B., Pogoda, P., Rueger, J. M., Püschel, K. & Amling, M., 2011, In: J TRAUMA. 70, 1, p. 154-158 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Trabecular reorganization in consecutive iliac crest biopsies when switching from bisphosphonate to strontium ranelate treatment.
Jobke, B., Burghardt, A. J., Muche, B., Hahn, M., Semler, J., Amling, M., Majumdar, S. & Busse, B., 2011, In: PLOS ONE. 6, 8, p. 23638 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2010
Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity.
Bartelt, A., Beil, F. T., Schinke, T., Röser, K., Ruether, W., Heeren, J. & Niemeier, A., 01.10.2010, In: BONE. 47, 4, p. 736-745 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.
Zustin, J., Akpalo, H., Gambarotti, M., Priemel, M., Rueger, J. M., Lübke, A., Reske, D., Lange, C., Püschel, K., Lohmann, C., Rüther, W., Amling, M. & Alberghini, M., 01.09.2010, In: AM J PATHOL. 177, 3, p. 1072-1078 7 p., 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation
Zaiss, M. M., Sarter, K., Hess, A., Engelke, K., Böhm, C., Nimmerjahn, F., Voll, R., Schett, G. & David, J-P., 01.08.2010, In: ARTHRITIS RHEUMATOL. 62, 8, p. 2328-38 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway
Krönke, G., Uderhardt, S., Kim, K-A., Stock, M., Scholtysek, C., Zaiss, M. M., Surmann-Schmitt, C., Luther, J., Katzenbeisser, J., David, J-P., Abdollahi-Roodsaz, S., Tran, K., Bright, J. M., Binnerts, M. E., Akhmetshina, A., Böhm, C., Distler, J. H., Joosten, L. A. B., Schett, G. & Abo, A., 01.08.2010, In: ARTHRITIS RHEUMATOL. 62, 8, p. 2303-12 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulatory T cells protect from local and systemic bone destruction in arthritis
Zaiss, M. M., Frey, B., Hess, A., Zwerina, J., Luther, J., Nimmerjahn, F., Engelke, K., Kollias, G., Hünig, T., Schett, G. & David, J-P., 15.06.2010, In: J IMMUNOL. 184, 12, p. 7238-46 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints
Uderhardt, S., Diarra, D., Katzenbeisser, J., David, J-P., Zwerina, J., Richards, W., Kronke, G. & Schett, G., 01.03.2010, In: ANN RHEUM DIS. 69, 3, p. 592-7 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones
Maes, C., Goossens, S., Bartunkova, S., Drogat, B., Coenegrachts, L., Stockmans, I., Moermans, K., Nyabi, O., Haigh, K., Naessens, M., Haenebalcke, L., Tuckermann, J. P., Tjwa, M., Carmeliet, P., Mandic, V., David, J-P., Behrens, A., Nagy, A., Carmeliet, G. & Haigh, J. J., 20.01.2010, In: EMBO J. 29, 2, p. 424-41 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Biomechanical evaluation of peri- and interprosthetic fractures of the femur.
Lehmann, W., Rupprecht, M., Hellmers, N., Sellenschloh, K., Briem, D., Püschel, K., Amling, M., Morlock, M. & Rueger, J. M., 2010, In: J TRAUMA. 68, 6, p. 1459-1463 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone.
Busse, B., Djonic, D., Milovanovic, P., Hahn, M., Püschel, K., Ritchie, R. O., Djuric, M. & Amling, M., 2010, In: AGING CELL. 9, 6, p. 1065-1075 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Die Moorleiche aus dem Mittelalter war Rechtshänder.
Barvencik, F., Pestka, J-M., Beil, F. T., Marshall, R-P., Fansa, M., Amling, M. & Püschel, K., 2010, Das Kind aus der Esterweger Dose: Dokumentation einer außergewöhnlichen Skelett-Moorleiche. Isensee-Verlag, p. 63-68 6 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Effects of estrogen on fracture healing in mice.
Beil, F. T., Barvencik, F., Gebauer, M., Seitz, S., Rueger, J. M., Ignatius, A., Pogoda, P., Schinke, T. & Amling, M., 2010, In: J TRAUMA. 69, 5, p. 1259-1265 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.
Bozec, A., Bakiri, L., Jimenez, M., Schinke, T., Amling, M. & Wagner, E. F., 2010, In: J CELL BIOL. 190, 6, p. 1093-1106 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Glucocorticoids suppress bone formation by attenuating osteoblast differentiation via the monomeric glucocorticoid receptor.
Rauch, A., Seitz, S., Baschant, U., Schilling, A., Illing, A., Stride, B., Kirilov, M., Mandic, V., Takacz, A., Schmidt-Ullrich, R., Ostermay, S., Schinke, T., Spanbroek, R., Zaiss, M. M., Angel, P. E., Lerner, U. H., David, J-P., Reichardt, H. M., Amling, M., Schütz, G. & Tuckermann, J. P., 2010, In: CELL METAB. 11, 6, p. 517-531 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High bone turnover and accumulation of osteoid in patients with neurofibromatosis 1.
Seitz, S., Schnabel, C., Busse, B., Schmidt, H., Beil, F. T., Friedrich, R., Schinke, T., Mautner, V. F. & Amling, M., 2010, In: OSTEOPOROSIS INT. 21, 1, p. 119-127 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Identification of molecular markers for articular cartilage.
Hissnauer, T. N., Baranowsky, A., Pestka, J-M., Streichert, T., Wiegandt, K., Goepfert, C., Beil, F. T., Albers, J., Schulze, J., Ueblacker, P., Petersen, J. P., Schinke, T., Meenen, N., Pörtner, R. & Amling, M., 2010, In: OSTEOARTHR CARTILAGE. 18, 12, p. 1630-1638 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased trabecular bone formation in mice lacking the growth factor midkine.
Neunaber, C., Catalá-Lehnen, P., Beil, F. T., Marshall, R-P., Kanbach, V., Baranowsky, A., Lehmann, W., Streichert, T., Ignatius, A., Muramatsu, T., Schinke, T. & Amling, M., 2010, In: J BONE MINER RES. 25, 8, p. 1724-1735 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.
Schulze, J., Seitz, S., Saito, H., Schneebauer, M., Marshall, R-P., Baranowsky, A., Busse, B., Schilling, A., Friedrich, F., Albers, J., Spiro, A. S., Zustin, J., Streichert, T., Ellwanger, K., Niehrs, C., Amling, M., Baron, R. & Schinke, T., 2010, In: PLOS ONE. 5, 4, p. 10309 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Novel complexities regarding BMPs and fracture healing.
Schinke, T. & Amling, M., 2010, In: J BONE MINER RES. 25, 6, p. 1193-1195 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteologische Untersuchungen einer Moorleiche aus dem Mittelalter.
Pestka, J-M., Barvencik, F., Beil, F. T., Marshall, R-P., Fansa, M., Amling, M. & Püschel, K., 2010, Das Kind aus der Esterweger Dose: Dokumentation einer außergewöhnlichen Skelett-Moorleiche. Isensee-Verlag, p. 57-62 6 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Preproenkephalin (Penk) is expressed in differentiated osteoblasts, and its deletion in Hyp mice partially rescues their bone mineralization defect.
Seitz, S., Barvencik, F., Gebauer, M., Albers, J., Schulze, J., Streichert, T., Amling, M. & Schinke, T., 2010, In: CALCIFIED TISSUE INT. 86, 4, p. 282-293 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Region-specific sex-dependent pattern of age-related changes of proximal femoral cancellous bone and its implications on differential bone fragility.
Djuric, M., Djonic, D., Milovanovic, P., Nikolic, S., Marshall, R-P., Marinkovic, J. & Hahn, M., 2010, In: CALCIFIED TISSUE INT. 86, 3, p. 192-201 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reorganization of the femoral cortex due to age-, sex-, and endoprosthetic-related effects emphasized by osteonal dimensions and remodeling.
Busse, B., Hahn, M., Schinke, T., Püschel, K., Duda, G. N. & Amling, M., 2010, In: J BIOMED MATER RES A. 92, 4, p. 1440-1451 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Skeletal analysis and comparison of bog bodies from Northern European peat bogs.
Pestka, J-M., Barvencik, F., Beil, F. T., Marshall, R-P., Jopp, E., Schilling, A., Bauerochse, A., Fansa, M., Püschel, K. & Amling, M., 2010, In: SCI NAT-HEIDELBERG. 97, 4, p. 393-402 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Synchrotron-microcomputed tomography studies of normal and pathological cranial sutures: further insight.
Regelsberger, J., Schmidt, T., Busse, B., Herzen, J., Tsokos, M., Amling, M. & Beckmann, F., 2010, In: J NEUROSURG-PEDIATR. 5, 3, p. 238-242 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation.
Maronde, E., Schilling, A., Seitz, S., Schinke, T., Schmutz, I., van der Horst, G., Amling, M. & Albrecht, U., 2010, In: PLOS ONE. 5, 7, p. 11527 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2009
The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss
Böhm, C., Hayer, S., Kilian, A., Zaiss, M. M., Finger, S., Hess, A., Engelke, K., Kollias, G., Krönke, G., Zwerina, J., Schett, G. & David, J-P., 01.11.2009, In: J IMMUNOL. 183, 9, p. 5938-47 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Osteoidosteom. Minimal-invasive, bildwandlergesteuerte Resektion und histopathologische Diagnosesicherung mittels Diamanthohlfräsen
Spiro, A. S., Zustin, J., Habermann, C., Meenen, N., Sauter, G., Amling, M., Rueger, J. M. & Priemel, M., 01.10.2009, In: ORTHOPADE. 38, 10, p. 962-969 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mesenchymale Stammzellen bei Arthritis
David, J-P., Zwerina, J. & Schett, G., 01.05.2009, In: Z RHEUMATOL. 68, 3, p. 228-33 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research