Institute for Neuroimmunology and Multiple Sclerosis

Publications

  1. 2023
  2. Vagus nerve inflammation contributes to dysautonomia in COVID-19

    Woo, M. S., Shafiq, M., Fitzek, A., Dottermusch, M., Altmeppen, H., Mohammadi, B., Mayer, C., Bal, L. C., Raich, L., Matschke, J., Krasemann, S., Pfefferle, S., Brehm, T. T., Lütgehetmann, M., Schädler, J., Addo, M. M., Schulze Zur Wiesch, J., Ondruschka, B., Friese, M. A. & Glatzel, M., 09.2023, In: ACTA NEUROPATHOL. 146, 3, p. 387-394 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Knowledge and worries on motherhood choice in multiple sclerosis - a cross-sectional study on patient-reported outcome measures

    Peper, J., Köpke, S., Solari, A., Giordano, A., Gold, S. M., Hellwig, K., Steinberg, L., Steckelberg, A., Heesen, C. & Rahn, A. C., 08.2023, In: MULT SCLER RELAT DIS. 76, p. 104789

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Update on the diagnosis and treatment of neuromyelits optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis

    Jarius, S., Aktas, O., Ayzenberg, I., Bellmann-Strobl, J., Berthele, A., Giglhuber, K., Häußler, V., Havla, J., Hellwig, K., Hümmert, M. W., Kleiter, I., Klotz, L., Krumbholz, M., Kümpfel, T., Paul, F., Ringelstein, M., Ruprecht, K., Senel, M., Stellmann, J-P., Bergh, F. T., Tumani, H., Wildemann, B., Trebst, C. & Neuromyelitis Optica Study Group (NEMOS), 07.2023, In: J NEUROL. 270, 7, p. 3341-3368 28 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  5. Associations between individual depressive symptoms and immunometabolic characteristics in major depression

    Chae, W. R., Baumert, J., Nübel, J., Brasanac, J., Gold, S. M., Hapke, U. & Otte, C., 06.2023, In: EUR NEUROPSYCHOPHARM. 71, p. 25-40 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Cognition in patients with neuromyelitis optica spectrum disorders: A prospective multicentre study of 217 patients (CogniNMO-Study)

    Hümmert, M. W., Stern, C., Paul, F., Duchow, A., Bellmann-Strobl, J., Ayzenberg, I., Schwake, C., Kleiter, I., Hellwig, K., Jarius, S., Wildemann, B., Senel, M., Berthele, A., Giglhuber, K., Luessi, F., Grothe, M., Klotz, L., Schülke, R., Gingele, S., Faiss, J. H., Walter, A., Warnke, C., Then Bergh, F., Aktas, O., Ringelstein, M., Stellmann, J-P., Häußler, V., Havla, J., Pellkofer, H., Kümpfel, T., Kopp, B., Trebst, C. & NEMOS (Neuromyelitis Optica Study Group), 06.2023, In: MULT SCLER J. 29, 7, p. 819-831 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Supporting brain health in multiple sclerosis: exploring the potential of neuroeducation combined with practical mindfulness exercises in the management of neuropsychological symptoms

    Baetge, S. J., Filser, M., Renner, A., Raithel, L. M., Lau, S., Pöttgen, J. & Penner, I-K., 06.2023, In: J NEUROL. 270, 6, p. 3058-3071 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Clinical surrogates of dysautonomia predict lethal outcome in COVID-19 on intensive care unit

    Woo, M. S., Mayer, C., Fischer, M., Kluge, S., Roedl, K., Gerloff, C., Czorlich, P., Thomalla, G., Schulze Zur Wiesch, J. & Schweingruber, N., 04.05.2023, In: Neurol Res Pract. 5, 1, p. 17

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Treatment of autoimmunity: The impact of disease-modifying therapies in multiple sclerosis and comorbid autoimmune disorders

    Konen, F. F., Möhn, N., Witte, T., Schefzyk, M., Wiestler, M., Lovric, S., Hufendiek, K., Schwenkenbecher, P., Sühs, K-W., Friese, M. A., Klotz, L., Pul, R., Pawlitzki, M., Hagin, D., Kleinschnitz, C., Meuth, S. G. & Skripuletz, T., 05.2023, In: AUTOIMMUN REV. 22, 5, p. 103312

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  10. Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination

    Kapell, H., Fazio, L., Dyckow, J., Schwarz, S., Cruz-Herranz, A., Mayer, C., Campos, J., D Este, E., Möbius, W., Cordano, C., Pröbstel, A-K., Gharagozloo, M., Zulji, A., Narayanan Naik, V., Delank, A-K., Cerina, M., Müntefering, T., Lerma-Martin, C., Sonner, J. K., Sin, J. H., Disse, P., Rychlik, N., Sabeur, K., Chavali, M., Srivastava, R., Heidenreich, M., Fitzgerald, K. C., Seebohm, G., Stadelmann, C., Hemmer, B., Platten, M., Jentsch, T. J., Engelhardt, M., Budde, T., Nave, K-A., Calabresi, P. A., Friese, M. A., Green, A. J., Acuna, C., Rowitch, D. H., Meuth, S. G. & Schirmer, L., 03.04.2023, In: J CLIN INVEST. 133, 7, e164223.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. The challenge of pregnancy in women with multiple sclerosis

    Heesen, C. & Rahn, A. C., 04.2023, In: LANCET NEUROL. 22, 4, p. 288-289 2 p.

    Research output: SCORING: Contribution to journalComment/debateResearch

  12. Effects of the COVID-19 Pandemic on Patients With NMO Spectrum Disorders and MOG-Antibody-Associated Diseases: COPANMO(G)-Study

    Hümmert, M. W., Bütow, F., Tkachenko, D., Ayzenberg, I., Pakeerathan, T., Hellwig, K., Klotz, L., Häußler, V., Stellmann, J-P., Warnke, C., Goereci, Y., Etgen, T., Luessi, F., Bronzlik, P., Gingele, S., Lauenstein, A-S., Kleiter, I., Rommer, P. S., Paul, F., Bellmann-Strobl, J., Duchow, A., Then Bergh, F., Pul, R., Walter, A., Pellkofer, H., Kümpfel, T., Pompsch, M., Kraemer, M., Albrecht, P., Aktas, O., Ringelstein, M., Senel, M., Giglhuber, K., Berthele, A., Jarius, S., Wildemann, B., Trebst, C. & Neuromyelitis Optica Study Group (NEMOS), 03.2023, In: NEUROL-NEUROIMMUNOL. 10, 2, e200082.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease

    Grochowska, K. M., Gomes, G. M., Raman, R., Kaushik, R., Sosulina, L., Kaneko, H., Oelschlegel, A. M., Yuanxiang, P., Reyes-Resina, I., Bayraktar, G., Samer, S., Spilker, C., Woo, M. S., Morawski, M., Goldschmidt, J., Friese, M. A., Rossner, S., Navarro, G., Remy, S., Reissner, C., Karpova, A. & Kreutz, M. R., 15.02.2023, In: EMBO J. 42, 4, e112453.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. CXCR5+PD-1++ CD4+ T cells colonize infant intestines early in life and promote B cell maturation

    Jordan-Paiz, A., Martrus, G., Steinert, F. L., Kaufmann, M., Sagebiel, A. F., Schreurs, R. R. C. E., Rechtien, A., Baumdick, M. E., Jung, J. M., Möller, K. J., Wegner, L., Grüttner, C., Richert, L., Thünauer, R., Schroeder-Schwarz, J., van Goudoever, J. B., Geijtenbeek, T. B. H., Altfeld, M., Pals, S. T., Perez, D., Klarenbeek, P. L., Tomuschat, C., Sauter, G., Königs, I., Schumacher, U., Friese, M. A., Melling, N., Reinshagen, K. & Bunders, M. J., 02.2023, In: CELL MOL IMMUNOL. 20, 2, p. 201-213 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. GPR52 regulates cAMP in T cells but is dispensable for encephalitogenic responses

    Krieg, P. F., Sonner, J. K., Kurelic, R., Engler, J. B., Scharenberg, M. F., Bauer, S., Nikolaev, V. O. & Friese, M. A., 24.01.2023, In: FRONT IMMUNOL. 13, 1113348.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. The manifestation of affective symptoms in multiple sclerosis and discussion of the currently available diagnostic assessment tools

    Filser, M., Buchner, A., Fink, G. R., Gold, S. M. & Penner, I-K., 01.2023, In: J NEUROL. 270, 1, p. 171-207 37 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  17. Topological reorganization of brain network might contribute to the resilience of cognitive functioning in mildly disabled relapsing remitting multiple sclerosis

    Has Silemek, A. C., Nolte, G., Pöttgen, J., Engel, A. K., Heesen, C., Gold, S. M. & Stellmann, J-P., 01.2023, In: J NEUROSCI RES. 101, 1, p. 143-161 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. A2A adenosine receptor-driven cAMP signaling in olfactory bulb astrocytes is unaffected in experimental autoimmune encephalomyelitis

    Wendlandt, M., Kürten, A. J., Beiersdorfer, A., Schubert, C., Samad-Yazdtchi, K., Sauer, J., Pinto, M. C., Schulz, K., Friese, M. A., Gee, C. E., Hirnet, D. & Lohr, C., 2023, In: FRONT IMMUNOL. 14, p. 1-10 1273837.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Absence of self-reported neuropsychiatric and somatic symptoms after Omicron variant SARS-CoV-2 breakthrough infections

    Woo, M. S., Mayer, C., Brehm, T. T., Andersen, G., Weigel, A., Löwe, B., Lohse, A. W., Addo, M. M., Gerloff, C., Knobloch, J. K. M., Schulze Zur Wiesch, J. & Friese, M. A., 2023, In: BRAIN COMMUN. 5, 2, p. fcad092

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Autologous haematopoietic stem cell transplantation for multiple sclerosis: a position paper and registry outline

    Bayas, A., Berthele, A., Blank, N., Dreger, P., Faissner, S., Friese, M. A., Gerdes, L-A., Grauer, O. M., Häussler, V., Heesen, C., Janson, D., Korporal-Kuhnke, M., Kowarik, M., Kröger, N., Lünemann, J. D., Martin, R., Meier, U., Meuth, S., Muraro, P., Platten, M., Schirmer, L., Stürner, K. H., Stellmann, J. P., Scheid, C., Bergh, F. T., Warnke, C., Wildemann, B., Ziemssen, T. & Task Force AHSCT Of The German Multiple Sclerosis Competence Network, 2023, In: THER ADV NEUROL DISO. 16, p. 17562864231180730

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Case report: JAK inhibition as promising treatment option of fatal RVCLS due to TREX1 mutation (pVAL235Glyfs*6)

    Ufer, F., Ziegler, S. M., Altfeld, M. & Friese, M. A., 2023, In: FRONT NEUROL. 14, 1118369.

    Research output: SCORING: Contribution to journalCase reportResearchpeer-review

  22. Editorial: Shared decision-making in neurology

    Heesen, C. & Solari, A., 2023, In: FRONT NEUROL. 14, 1222433.

    Research output: SCORING: Contribution to journalEditorialResearch

  23. Effect of geometric distortion correction on thickness and volume measurements of cortical parcellations in 3D T1w gradient echo sequences

    Thaler, C., Sedlacik, J., Forkert, N. D., Stellmann, J-P., Schön, G., Fiehler, J. & Gellißen, S., 2023, In: PLOS ONE. 18, 4, e0284440.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. eHealth für MS-Betroffene mit Fatigue

    Pöttgen, J. & Penner, I-K., 2023, In: PiD-Psychother Dialog. 2023, 24, p. 1-4 4 p., 24.

    Research output: SCORING: Contribution to journalNewspaper articlesTransfer

  25. Endothelial Indoleamine-2,3-Dioxygenase-1 is not Critically Involved in Regulating Antitumor Immunity in the Central Nervous System

    Abu Hejleh, A. P., Huck, K., Jähne, K., Tan, C. L., Lanz, T. V., Epping, L., Sonner, J. K., Meuth, S. G., Henneberg, A., Opitz, C. A., Herold-Mende, C., Sahm, F., Platten, M. & Sahm, K., 2023, In: INT J TRYPTOPHAN RES. 16

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Health behaviors of people with multiple sclerosis and its associations with MS related outcomes: a German clinical cohort

    Goldin, K., Riemann-Lorenz, K., Daubmann, A., Pöttgen, J., Krause, N., Schröder, H. & Heesen, C., 2023, In: FRONT NEUROL. 14, p. 1172419

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. The Psychosocial Impact of Parental Multiple Sclerosis on Children and Adolescents: A Systematic Review

    Haker, M., Peper, J., Haagen, M., Heesen, C. & Rahn, A. C., 2023, In: Int J MS Care. 25, 2, p. 63-70 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  28. 2022
  29. Communicating with people with MS: A key role for evidence-based patient information

    Heesen, C., Rahn, A. C. & Köpke, S., 12.2022, In: PATIENT EDUC COUNS. 105, 12, p. 3339-3340 2 p.

    Research output: SCORING: Contribution to journalEditorialResearch

  30. The immunology of multiple sclerosis

    Attfield, K. E., Jensen, L. T., Kaufmann, M., Friese, M. A. & Fugger, L., 12.2022, In: NAT REV IMMUNOL. 22, 12, p. 734–750 17 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  31. Driving ability and predictors for driving performance in Multiple Sclerosis: A systematic review

    Seddiq Zai, S., Heesen, C., Buhmann, C., das Nair, R. & Pöttgen, J., 30.11.2022, In: FRONT NEUROL. 13, 1056411.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  32. Neandertal introgression partitions the genetic landscape of neuropsychiatric disorders and associated behavioral phenotypes

    Dannemann, M., Milaneschi, Y., Yermakovich, D., Stiglbauer, V., Kariis, H. M., Krebs, K., Friese, M. A., Otte, C., Estonian Biobank Research Team, Lehto, K., Penninx, B. W. J. H., Kelso, J. & Gold, S. M., 05.10.2022, In: TRANSL PSYCHIAT. 12, 1, 433.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Erratum to "Digital tools for the assessment of pharmacological treatment for depressive disorder: State of the Art. [European Neuropsychopharmacology 60 (2022) 100-116]"

    Van Assche, E., Ramos-Quiroga, J. A., Pariante, C. M., Sforzini, L., Young, A. H., Flossbach, Y., Gold, S. M., Hoogendijk, W. J. G., Baune, B. T. & Maron, E., 10.2022, In: EUR NEUROPSYCHOPHARM. 63, p. 4-5 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  34. An interactive web-based programme on relapse management for people with multiple sclerosis (POWER@MS2) - development, feasibility, and pilot testing of a complex intervention

    Wenzel, L., Heesen, C., Peper, J., Grentzenberg, K., Faßhauer, E., Scheiderbauer, J., Thale, F., Meyer, B., Köpke, S. & Rahn, A. C., 23.09.2022, In: FRONT NEUROL. 13, 914814.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system

    Klein, M., Kaleem, A., Oetjen, S., Wünkhaus, D., Binkle, L., Schilling, S., Gjorgjieva, M., Scholz, R., Gruber-Schoffnegger, D., Storch, S., Kins, S., Drewes, G., Hoffmeister-Ullerich, S., Kuhl, D. & Hermey, G., 09.2022, In: AUTOPHAGY. 18, 9, p. 2068-2085 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Validation of the German eHealth impact questionnaire for online health information users affected by multiple sclerosis

    Sippel, A., Riemann-Lorenz, K., Pöttgen, J., Wiedemann, R., Drixler, K., Bitzer, E. M., Holmberg, C., Lezius, S. & Heesen, C., 16.08.2022, In: BMC MED INFORM DECIS. 22, 1, 219.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. On model-based time trend adjustments in platform trials with non-concurrent controls

    Roig, M. B., Krotka, P., Burman, C-F., Glimm, E., Gold, S. M., Hees, K., Jacko, P., Koenig, F., Magirr, D., Mesenbrink, P., Viele, K. & Posch, M., 15.08.2022, In: BMC MED RES METHODOL. 22, 1, 228.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis

    Rothammer, N., Woo, M. S., Bauer, S., Binkle-Ladisch, L., Di Liberto, G., Egervari, K., Wagner, I., Haferkamp, U., Pless, O., Merkler, D., Engler, J. B. & Friese, M. A., 05.08.2022, In: SCI ADV. 8, 31, eabm5500.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Immunotherapy for people with clinically isolated syndrome or relapsing-remitting multiple sclerosis: treatment response by demographic, clinical, and biomarker subgroups (PROMISE)-a systematic review protocol

    Lehnert, T., Röver, C., Köpke, S., Rio, J., Chard, D., Fittipaldo, A. V., Friede, T., Heesen, C. & Rahn, A. C., 01.07.2022, In: SYST REV-LONDON. 11, 1, 134.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Association of depression and obesity with C-reactive protein in Germany: a large nationally representative study

    Ri Chae, W., Nübel, J., Baumert, J., Gold, S. M. & Otte, C., 07.2022, In: BRAIN BEHAV IMMUN. 103, p. 223-231 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. German guideline for diagnosis and treatment of multiple sclerosis - a survey focusing neurologists in daily practise

    Heesen, C., Mokry, C., Salmen, A., Hegen, H., Mäurer, M., Warnke, C., Gehring, K., Berthele, A. & Meier, U., 07.2022, In: MULT SCLER RELAT DIS. 63, 103828.

    Research output: SCORING: Contribution to journalLetterResearch

  42. Identification of early neurodegenerative pathways in progressive multiple sclerosis

    Kaufmann, M., Schaupp, A-L., Sun, R., Coscia, F., Dendrou, C. A., Cortes, A., Kaur, G., Evans, H. G., Mollbrink, A., Navarro, J. F., Sonner, J. K., Mayer, C., DeLuca, G. C., Lundeberg, J., Matthews, P. M., Attfield, K. E., Friese, M. A., Mann, M. & Fugger, L., 07.2022, In: NAT NEUROSCI. 25, 7, p. 944-955 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Motherhood choice in multiple sclerosis (MoMS) development and piloting of patient-reported outcome measures

    Steinberg, L., Peper, J., Köpke, S., Solari, A., Giordano, A., Gold, S. M., Hellwig, K., Heesen, C. & Rahn, A. C., 07.2022, In: MULT SCLER RELAT DIS. 63, 103831.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. The Sylvia Lawry Centre for Multiple Sclerosis Research (SLCMSR)--Critical review facing the 20 anniversary

    Heesen, C., Magyari, M., Stellmann, J. P., Lederer, C., Giovannoni, G., Scalfari, A. & Daumer, M., 07.2022, In: MULT SCLER RELAT DIS. 63, 103885.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  45. Negative Associations of Stress and Anxiety Levels With Cytotoxic and Regulatory Natural Killer Cell Frequency in Chronic Tinnitus

    Basso, L., Boecking, B., Neff, P., Brueggemann, P., El-Ahmad, L., Brasanac, J., Rose, M., Gold, S. M. & Mazurek, B., 23.06.2022, In: FRONT PSYCHOL. 13, 871822.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Entwicklung und Machbarkeitstestung einer evidenzbasierten Ernährungs-Information zur Multiplen Sklerose (NUTRIMS)

    Riemann-Lorenz, K. & Heesen, C., 14.06.2022, In: AKTUEL ERNAHRUNGSMED. 47, 3, 232.

    Research output: SCORING: Contribution to journalConference abstract in journalResearchpeer-review

  47. Experiences of persons with multiple sclerosis with rehabilitation-a qualitative interview study

    Ghaidar, D., Sippel, A., Riemann-Lorenz, K., Kofahl, C., Morrison, R., Kleiter, I., Schmidt, S., Dettmers, C., Schulz, H. & Heesen, C., 11.06.2022, In: BMC HEALTH SERV RES. 22, 1, 770.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Brain grey matter perfusion in primary progressive multiple sclerosis: Mild decrease over years and regional associations with cognition and hand function

    Testud, B., Delacour, C., El Ahmadi, A. A., Brun, G., Girard, N., Duhamel, G., Heesen, C., Häußler, V., Thaler, C., Has Silemek, A. C. & Stellmann, J-P., 06.2022, In: EUR J NEUROL. 29, 6, p. 1741-1752 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Experiences of persons with Multiple Sclerosis with lifestyle adjustment-A qualitative interview study

    Elkhalii-Wilhelm, S., Sippel, A., Riemann-Lorenz, K., Kofahl, C., Scheiderbauer, J., Arnade, S., Kleiter, I., Schmidt, S. & Heesen, C., 27.05.2022, In: PLOS ONE. 17, 5, e0268988.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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