Research ExplorerResearch UnitsInstitute for Immunology Publications

Institute for Immunology

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Publications

  1. 2003

  2. Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis

    Tolosa, E., Li, W., Yasuda, Y., Wienhold, W., Denzin, L. K., Lautwein, A., Driessen, C., Schnorrer, P., Weber, E., Stevanovic, S., Kurek, R., Melms, A. & Bromme, D., 01.08.2003, In: J CLIN INVEST. 112, 4, p. 517-26 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  3. The CD28 related molecule ICOS: T cell modulation in the presence and absence of B7.1/2 and regulational expression in multiple sclerosis

    Wiendl, H., Neuhaus, O., Mehling, M., Wintterle, S., Schreiner, B., Mitsdoerffer, M., Wienhold, W., Weissert, R., Wessels, J., Hartung, H-P., Weller, M., Tolosa, E. & Melms, A., 01.07.2003, In: J NEUROIMMUNOL. 140, 1-2, p. 177-87 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  4. Antigen processing and presentation in human muscle: cathepsin S is critical for MHC class II expression and upregulated in inflammatory myopathies

    Wiendl, H., Lautwein, A., Mitsdörffer, M., Krause, S., Erfurth, S., Wienhold, W., Morgalla, M., Weber, E., Overkleeft, H. S., Lochmüller, H., Melms, A., Tolosa, E. & Driessen, C., 01.05.2003, In: J NEUROIMMUNOL. 138, 1-2, p. 132-43 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  5. Flow cytometric and immunoblot assays for cell surface ADP-ribosylation using a monoclonal antibody specific for ethenoadenosine

    Krebs, C., Koestner, W., Nissen, M., Welge, V., Parusel, I., Malavasi, F., Leiter, E. H., Santella, R. M., Haag, F. & Koch-Nolte, F., 01.03.2003, In: ANAL BIOCHEM. 314, 1, p. 108-15 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  6. Detecting panic disorder in medical and psychosomatic outpatients: comparative validation of the Hospital Anxiety and Depression Scale, the Patient Health Questionnaire, a screening question, and physicians' diagnosis.

    Löwe, B., Gräfe, K., Zipfel, S., Spitzer, R. L., Herrmann-Lingen, C., Witte, S. & Herzog, W., 2003, In: J PSYCHOSOM RES. 55, 6, p. 515-519 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  7. Predictors of psychiatric comorbidity in medical outpatients.

    Löwe, B., Gräfe, K., Kroenke, K., Zipfel, S., Quenter, A., Wild, B., Fiehn, C. & Herzog, W., 2003, In: PSYCHOSOM MED. 65, 5, p. 764-770 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  8. 2002

  9. Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses

    Kursar, M., Bonhagen, K., Fensterle, J., Köhler, A., Hurwitz, R., Kamradt, T., Kaufmann, S. H. E. & Mittrücker, H-W., 16.12.2002, In: J EXP MED. 196, 12, p. 1585-92 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  10. Inducible costimulator protein controls the protective T cell response against Listeria monocytogenes

    Mittrücker, H-W., Kursar, M., Köhler, A., Yanagihara, D., Yoshinaga, S. K. & Kaufmann, S. H. E., 15.11.2002, In: J IMMUNOL. 169, 10, p. 5813-7 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  11. Macrophage migration inhibitory factor (MIF) plays a pivotal role in immunity against Salmonella typhimurium

    Koebernick, H., Grode, L., David, J. R., Rohde, W., Rolph, M. S., Mittrücker, H-W. & Kaufmann, S. H. E., 15.10.2002, In: P NATL ACAD SCI USA. 99, 21, p. 13681-6 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  12. Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4

    Lohoff, M., Mittrücker, H-W., Prechtl, S., Bischof, S., Sommer, F., Kock, S., Ferrick, D. A., Duncan, G. S., Gessner, A. & Mak, T. W., 03.09.2002, In: P NATL ACAD SCI USA. 99, 18, p. 11808-12 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  13. Organ-specific CD4+ T cell response during Listeria monocytogenes infection

    Kursar, M., Bonhagen, K., Köhler, A., Kamradt, T., Kaufmann, S. H. E. & Mittrücker, H-W., 15.06.2002, In: J IMMUNOL. 168, 12, p. 6382-7 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  14. Characterization of the murine T-lymphocyte response to Salmonella enterica serovar Typhimurium infection

    Mittrücker, H-W., Köhler, A. & Kaufmann, S. H. E., 01.01.2002, In: INFECT IMMUN. 70, 1, p. 199-203 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  15. 2001

  16. Role of CD28 for the generation and expansion of antigen-specific CD8(+) T lymphocytes during infection with Listeria monocytogenes

    Mittrücker, H. W., Kursar, M., Köhler, A., Hurwitz, R. & Kaufmann, S. H., 15.11.2001, In: J IMMUNOL. 167, 10, p. 5620-7 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  17. 2000

  18. Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells

    Lohoff, M., Duncan, G. S., Ferrick, D., Mittrücker, H. W., Bischof, S., Prechtl, S., Röllinghoff, M., Schmitt, E., Pahl, A. & Mak, T. W., 07.08.2000, In: J EXP MED. 192, 3, p. 325-36 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  19. Immune response to infection with Salmonella typhimurium in mice

    Mittrücker, H. W. & Kaufmann, S. H., 01.04.2000, In: J LEUKOCYTE BIOL. 67, 4, p. 457-63 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  20. Substantial in vivo proliferation of CD4(+) and CD8(+) T lymphocytes during secondary Listeria monocytogenes infection

    Mittrücker, H. W., Köhler, A. & Kaufmann, S. H., 01.04.2000, In: EUR J IMMUNOL. 30, 4, p. 1053-9 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  21. Cutting edge: role of B lymphocytes in protective immunity against Salmonella typhimurium infection

    Mittrücker, H. W., Raupach, B., Köhler, A. & Kaufmann, S. H., 15.02.2000, In: J IMMUNOL. 164, 4, p. 1648-52 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  22. 1999

  23. Critical role of CD28 in protective immunity against Salmonella typhimurium

    Mittrücker, H. W., Köhler, A., Mak, T. W. & Kaufmann, S. H., 15.12.1999, In: J IMMUNOL. 163, 12, p. 6769-76 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  24. Genomic instability in Gadd45a-deficient mice

    Hollander, M. C., Sheikh, M. S., Bulavin, D. V., Lundgren, K., Augeri-Henmueller, L., Shehee, R., Molinaro, T. A., Kim, K. E., Tolosa, E., Ashwell, J. D., Rosenberg, M. P., Zhan, Q., Fernández-Salguero, P. M., Morgan, W. F., Deng, C. X. & Fornace, A. J., 01.10.1999, In: NAT GENET. 23, 2, p. 176-84 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  25. A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+)CD8(+) thymocytes

    King, L. B., Tolosa, E., Lenczowski, J. M., Lu, F., Lind, E. F., Hunziker, R., Petrie, H. T. & Ashwell, J. D., 01.08.1999, In: INT IMMUNOL. 11, 8, p. 1203-16 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  26. Critical role of leukocyte function-associated antigen-1 in liver accumulation of CD4+NKT cells

    Emoto, M., Mittrücker, H. W., Schmits, R., Mak, T. W. & Kaufmann, S. H., 01.05.1999, In: J IMMUNOL. 162, 9, p. 5094-8 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  27. Thymus-derived glucocorticoids and the regulation of antigen-specific T-cell development

    Tolosa, E. & Ashwell, J. D., 1999, In: NEUROIMMUNOMODULAT. 6, 1-2, p. 90-6 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  28. 1998

  29. Receptor-specific allelic exclusion of TCRV alpha-chains during development

    Boyd, R., Kozieradzki, I., Chidgey, A., Mittrücker, H. W., Bouchard, D., Timms, E., Kishihara, K., Ong, C. J., Chui, D., Marth, J. D., Mak, T. W. & Penninger, J. M., 15.08.1998, In: J IMMUNOL. 161, 4, p. 1718-27 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  30. Triptolide induces apoptotic death of T lymphocyte

    Yang, Y., Liu, Z., Tolosa, E., Yang, J. & Li, L., 01.08.1998, In: IMMUNOPHARMACOLOGY. 40, 2, p. 139-49 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  31. Cytokine-dependent abortion in CBA x DBA/2 mice is mediated by the procoagulant fgl2 prothrombinase [correction of prothombinase]

    Clark, D. A., Chaouat, G., Arck, P. C., Mittrücker, H-W. & Levy, G. A., 15.01.1998, In: J IMMUNOL. 160, 2, p. 545-9 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  32. Thymocyte glucocorticoid resistance alters positive selection and inhibits autoimmunity and lymphoproliferative disease in MRL-lpr/lpr mice

    Tolosa, E., King, L. B. & Ashwell, J. D., 01.01.1998, In: IMMUNITY. 8, 1, p. 67-76 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  33. 1997

  34. CD2-mediated signaling in T cells lacking the zeta-chain-specific immune receptor tyrosine-based activation (ITAM) motif

    Steeg, C., von Bonin, A., Mittrücker, H. W., Malissen, B. & Fleischer, B., 01.09.1997, In: EUR J IMMUNOL. 27, 9, p. 2233-8 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  35. The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes

    Penninger, J. M., Sirard, C., Mittrücker, H. W., Chidgey, A., Kozieradzki, I., Nghiem, M., Hakem, A., Kimura, T., Timms, E., Boyd, R., Taniguchi, T., Matsuyama, T. & Mak, T. W., 01.08.1997, In: IMMUNITY. 7, 2, p. 243-54 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  36. Hyperexpression of transporter in antigen processing-1 (TAP-1) in thyroid glands affected by autoimmunity: a contributing factor to the breach of tolerance to thyroid antigens?

    Sospedra, M., Tolosa, E., Armengol, P., Ashhab, Y., Urlinger, S., Lucas-Martin, A., Foz-Sala, M., Jaraquemada, D. & Pujol-Borrell, R., 01.07.1997, In: CLIN EXP IMMUNOL. 109, 1, p. 98-106 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  37. Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo

    Lohoff, M., Ferrick, D., Mittrucker, H. W., Duncan, G. S., Bischof, S., Rollinghoff, M. & Mak, T. W., 01.06.1997, In: IMMUNITY. 6, 6, p. 681-9 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  38. The T-cell receptor associated zeta-chain is required but not sufficient for CD26 (dipeptidylpeptidase IV) mediated signaling

    von Bonin, A., Steeg, C., Mittrücker, H. W. & Fleischer, B., 01.03.1997, In: IMMUNOL LETT. 55, 3, p. 179-82 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  39. 1996

  40. The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo

    Duncan, G. S., Mittrücker, H. W., Kägi, D., Matsuyama, T. & Mak, T. W., 01.11.1996, In: J EXP MED. 184, 5, p. 2043-8 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  41. Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25

    Grossman, A., Mittrücker, H. W., Nicholl, J., Suzuki, A., Chung, S., Antonio, L., Suggs, S., Sutherland, G. R., Siderovski, D. P. & Mak, T. W., 15.10.1996, In: GENOMICS. 37, 2, p. 229-33 5 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  42. CTLA-4, a negative regulator of T-lymphocyte activation

    Waterhouse, P., Marengère, L. E., Mittrücker, H. W. & Mak, T. W., 01.10.1996, In: IMMUNOL REV. 153, p. 183-207 25 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  43. Duration of TCR stimulation determines costimulatory requirement of T cells

    Kündig, T. M., Shahinian, A., Kawai, K., Mittrücker, H. W., Sebzda, E., Bachmann, M. F., Mak, T. W. & Ohashi, P. S., 01.07.1996, In: IMMUNITY. 5, 1, p. 41-52 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  44. A fluorogenic assay of endogenous phosphatase for assessment of cell adhesion

    Tolosa, E. & Shaw, S., 10.06.1996, In: J IMMUNOL METHODS. 192, 1-2, p. 165-72 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  45. Induction of unresponsiveness and impaired T cell expansion by staphylococcal enterotoxin B in CD28-deficient mice

    Mittrücker, H. W., Shahinian, A., Bouchard, D., Kündig, T. M. & Mak, T. W., 01.06.1996, In: J EXP MED. 183, 6, p. 2481-8 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  46. Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

    Marengère, L. E., Waterhouse, P., Duncan, G. S., Mittrücker, H. W., Feng, G. S. & Mak, T. W., 24.05.1996, In: SCIENCE. 272, 5265, p. 1170-3 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  47. Impaired negative selection of T cells in Hodgkin's disease antigen CD30-deficient mice

    Amakawa, R., Hakem, A., Kundig, T. M., Matsuyama, T., Simard, J. J., Timms, E., Wakeham, A., Mittrücker, H-W., Griesser, H., Takimoto, H., Schmits, R., Shahinian, A., Ohashi, P., Penninger, J. M., Mak, T. W. & Mittrücker, H-W., 23.02.1996, In: CELL. 84, 4, p. 551-62 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  48. 1995

  49. T-lymphocyte development and function in gene-targeted mutant mice

    Mittrücker, H. W., Pfeffer, K., Schmits, R. & Mak, T. W., 01.12.1995, In: IMMUNOL REV. 148, p. 115-50 36 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  50. MSH2 deficient mice are viable and susceptible to lymphoid tumours

    Reitmair, A. H., Schmits, R., Ewel, A., Bapat, B., Redston, M., Mitri, A., Waterhouse, P., Mittrücker, H. W., Wakeham, A. & Liu, B., 01.09.1995, In: NAT GENET. 11, 1, p. 64-70 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  51. Molecular cloning of LSIRF, a lymphoid-specific member of the interferon regulatory factor family that binds the interferon-stimulated response element (ISRE)

    Matsuyama, T., Grossman, A., Mittrücker, H. W., Siderovski, D. P., Kiefer, F., Kawakami, T., Richardson, C. D., Taniguchi, T., Yoshinaga, S. K. & Mak, T. W., 25.06.1995, In: NUCLEIC ACIDS RES. 23, 12, p. 2127-36 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  52. Hyperinducibility of HLA class II expression of thyroid follicular cells from Graves' disease. A primary defect?

    Sospedra, M., Obiols, G., Babi, L. F., Tolosa, E., Vargas, F., Roura-Mir, C., Lucas-Martin, A., Ercilla, G. & Pujol-Borrell, R., 15.04.1995, In: J IMMUNOL. 154, 8, p. 4213-22 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  53. The cytoplasmic tail of the T cell receptor zeta chain is required for signaling via CD26

    Mittrücker, H. W., Steeg, C., Malissen, B. & Fleischer, B., 01.01.1995, In: EUR J IMMUNOL. 25, 1, p. 295-7 3 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  54. 1994

  55. Characterization of neural cell adhesion molecule (NCAM) expression in thyroid follicular cells: induction by cytokines and over-expression in autoimmune glands

    Vargas, F., Tolosa, E., Sospedra, M., Catálfamo, M., Lucas-Martín, A., Obiols, G. & Pujol-Borrell, R., 01.12.1994, In: CLIN EXP IMMUNOL. 98, 3, p. 478-88 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  56. 1993

  57. Enzymatic activity of CD26 (dipeptidylpeptidase IV) is not required for its signalling function in T cells

    Hegen, M., Mittrücker, H. W., Hug, R., Demuth, H. U., Neubert, K., Barth, A. & Fleischer, B., 01.12.1993, In: IMMUNOBIOLOGY. 189, 5, p. 483-93 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  58. Blood B, T, CD4+ and CD8+ lymphocytes in female Wistar rats

    Franch, A., Castellote, C., Pelegrí, C., Tolosa, E. & Castell, M., 01.09.1993, In: ANN HEMATOL. 67, 3, p. 115-8 4 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  59. Prognostic impact of mutated K-ras gene in surgically resected non-small cell lung cancer patients

    Rosell, R., Li, S., Skacel, Z., Mate, J. L., Maestre, J., Canela, M., Tolosa, E., Armengol, P., Barnadas, A. & Ariza, A., 01.09.1993, In: ONCOGENE. 8, 9, p. 2407-12 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  60. Herpes virus saimiri-transformed human T lymphocytes: normal functional phenotype and preserved T cell receptor signalling

    Mittrücker, H. W., Müller-Fleckenstein, I., Fleckenstein, B. & Fleischer, B., 01.08.1993, In: INT IMMUNOL. 5, 8, p. 985-90 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

  61. Gamma delta lymphocytes in endocrine autoimmunity: evidence of expansion in Graves' disease but not in type 1 diabetes

    Roura-Mir, I. C., Alcalde, L., Vargas, F., Tolosa, E., Obiols, G., Foz, M., Jaraquemada, D. & Pujol-Borrell, R., 01.05.1993, In: CLIN EXP IMMUNOL. 92, 2, p. 288-95 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

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