Institute for Immunology

Publications

  1. 2007
  2. Autophagic cell death induced by TrkA receptor activation in human glioblastoma cells.

    Hansen, K., Wagner, B., Hamel, W., Schweizer, M., Haag, F., Westphal, M. & Lamszus, K., 2007, In: J NEUROCHEM. 103, 1, p. 259-275 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. CD83 is a regulator of murine B cell function in vivo.

    Breloer, M., Kretschmer, B., Lüthje, K., Ehrlich, S., Ritter, U., Bickert, T., Steeg, C., Fillatreau, S., Hoehlig, K., Lampropoulou, V. & Fleischer, B., 2007, In: EUR J IMMUNOL. 37, 3, p. 634-648 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. CD83 modulates B Cell function in vitro: increased IL-10 and reduced Ig secretion by CD83Tg B cells.

    Kretschmer, B., Lüthje, K., Guse, A. H., Ehrlich, S., Koch Nolte, F., Haag, F., Fleischer, B. & Breloer, M., 2007, In: PLOS ONE. 2, 1, p. 755 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Chemokine receptor CXCR3 mediates T cell recruitment and tissue injury in nephrotoxic nephritis in mice.

    Panzer, U., Steinmetz, O., Paust, H-J., Meyer-Schwesinger, C., Peters, A., Turner, J. E., Zahner, G., Heymann, F., Kurts, C., Hopfer, H., Helmchen, U., Haag, F., Schneider, A. & Stahl, R. A. K., 2007, In: J AM SOC NEPHROL. 18, 7, p. 2071-2084 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Cloning and characterization of an adenoviral vector for highly efficient and doxycycline-suppressible expression of bioactive human single-chain interleukin 12 in colon cancer.

    Wulff, H., Krieger, T., Krüger, K., Stahmer, I., Thaiss, F., Schäfer, H. & Block, A., 2007, In: BMC BIOTECHNOL. 7, p. 35

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. CTLA-4 blockade differentially influences the outcome of non-lethal and lethal Plasmodium yoelii infections.

    Lepenies, B., Gaworski, I., Tartz, S., Langhorne, J., Fleischer, B. & Jacobs, T., 2007, In: MICROBES INFECT. 9, 6, p. 687-694 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis.

    Kursar, M., Koch, M., Mittrücker, H. W., Nouailles, G., Bonhagen, K., Kamradt, T. & Kaufmann, S. H. E., 2007, In: J IMMUNOL. 178, 5, p. 2661-2665 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Dementia and leukoencephalopathy due to lymphomatosis cerebri.

    Lewerenz, J., Ding, X., Matschke, J., Schnabel, C., Emami, P., von Borczyskowski, D., Buchert, R., Krieger, T., De Wit, M. & Münchau, A., 2007, In: J NEUROL NEUROSUR PS. 78, 7, p. 777-778 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Extracellular NAD and ATP: Partners in immune cell modulation.

    Haag, F., Adriouch, S., Brass, A., Jung, C., Hübener, S., Scheuplein, F., Bannas, P., Seman, M. & Koch-Nolte, F., 2007, In: PURINERG SIGNAL. 3, 1-2, p. 71-81 1-2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. FK778 in experimental xenotransplantation: a detailed analysis of drug efficacy.

    Schrepfer, S., Deuse, T., Koch Nolte, F., Krieger, T., Haddad, M., Schäfer, H., Pelletier, M. P., Robbins, R. C. & Reichenspurner, H., 2007, In: J HEART LUNG TRANSPL. 26, 1, p. 70-77 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Higher frequency of regulatory T cells in the elderly and increased suppressive activity in neurodegeneration.

    Rosenkranz, D., Weyer, S., Tolosa, E., Gaenslen, A., Berg, D., Leyhe, T., Gasser, T. & Stoltze, L., 2007, In: J NEUROIMMUNOL. 188, 1-2, p. 117-127 1-2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation.

    Feger, U., Tolosa, E., Huang, Y-H., Waschbisch, A., Biedermann, T., Melms, A. & Wiendl, H., 2007, In: BLOOD. 110, 2, p. 568-577 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Human CD4+ T cells displaying viral epitopes elicit a functional virus-specific memory CD8+ T cell response.

    Adamopoulou, E., Diekmann, J., Tolosa, E., Kuntz, G., Einsele, H., Rammensee, H-G. & Topp, M. S., 2007, In: J IMMUNOL. 178, 9, p. 5465-5472 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Lipopolysaccharide, IFN-gamma, and IFN-beta induce expression of the thiol-sensitive ART2.1 Ecto-ADP-ribosyltransferase in murine macrophages.

    Hong, S., Brass, A., Seman, M., Haag, F., Koch Nolte, F. & Dubyak, G. R., 2007, In: J IMMUNOL. 179, 9, p. 6215-6227 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation.

    Hübener, S., Jung, C., Adriouch, S., Dubberke, G., Seyfried, F., Seman, M., Haag, F. & Koch Nolte, F., 2007, In: PURINERG SIGNAL. 3, 4, p. 359-366 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. NAD+ released during inflammation participates in T cell homeostasis by inducing ART2-mediated death of naive T cells in vivo.

    Adriouch, S., Hubert, S., Pechberty, S., Koch Nolte, F., Haag, F. & Seman, M., 2007, In: J IMMUNOL. 179, 1, p. 186-194 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.

    Viken, M. K., Sollid, H. D., Joner, G., Dahl-Jørgensen, K., Rønningen, K. S., Undlien, D. E., Flatø, B., Selvaag, A. M., Førre, Ø., Kvien, T. K., Thorsby, E., Melms, A., Tolosa, E. & Lie, B. A., 2007, In: HUM IMMUNOL. 68, 9, p. 748-755 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis.

    Mittrücker, H. W., Steinhoff, U., Köhler, A., Krause, M., Lazar, D., Mex, P., Miekley, D. & Kaufmann, S. H. E., 2007, In: P NATL ACAD SCI USA. 104, 30, p. 12434-12439 30.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Regional IFNgamma expression is insufficient for efficacious control of food-borne bacterial pathogens at the gut epithelial barrier.

    Gajendran, N., Mittrücker, H. W., Bordasch, K., Heinemann, E., Koch, M. & Kaufmann, S. H. E., 2007, In: INT IMMUNOL. 19, 9, p. 1075-1081 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo.

    Koch Nolte, F., Reyelt, J., Schössow, B., Schwarz, N., Scheuplein, F., Rothenburg, S., Haag, F., Alzogaray, V., Cauerhff, A. & Goldbaum, F. A., 2007, In: FASEB J. 21, 13, p. 3490-3498 13.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Standardization of autoimmune diagnostics in Germany: activities of the German group in the European Autoimmune Standardization Initiative.

    Sack, U., Conrad, K., Csernok, E., Frank, I., Haass, M., Krieger, T., Seyfarth, M., Schlosser, U., Schmidt, R. E. & Witte, T., 2007, In: ANN NY ACAD SCI. 1109, p. 31-36

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. 2006
  24. Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules

    Drumea-Mirancea, M., Wessels, J. T., Müller, C. A., Essl, M., Eble, J. A., Tolosa, E., Koch, M., Reinhardt, D. P., Sixt, M., Sorokin, L., Stierhof, Y-D., Schwarz, H. & Klein, G., 01.04.2006, In: J CELL SCI. 119, Pt 7, p. 1396-405 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Medical patients' attitudes toward emotional problems and their treatment. What do they really want?

    Löwe, B., Schulz, U., Gräfe, K. & Wilke, S., 2006, In: J GEN INTERN MED. 21, 1, p. 39-45 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. 2005
  27. Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells

    Burster, T., Beck, A., Tolosa, E., Schnorrer, P., Weissert, R., Reich, M., Kraus, M., Kalbacher, H., Häring, H-U., Weber, E., Overkleeft, H. & Driessen, C., 01.11.2005, In: J IMMUNOL. 175, 9, p. 5940-9 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. Expression of insulin-like factor 3 protein in the rat testis during fetal and postnatal development and in relation to cryptorchidism induced by in utero exposure to di (n-Butyl) phthalate

    McKinnell, C., Sharpe, R. M., Mahood, K., Hallmark, N., Scott, H., Ivell, R., Staub, C., Jégou, B., Haag, F., Koch-Nolte, F. & Hartung, S., 01.10.2005, In: ENDOCRINOLOGY. 146, 10, p. 4536-44 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo

    Wiemann, K., Mittrücker, H-W., Feger, U., Welte, S. A., Yokoyama, W. M., Spies, T., Rammensee, H-G. & Steinle, A., 15.07.2005, In: J IMMUNOL. 175, 2, p. 720-9 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Autistic effector T cells in mice with a point mutation in the LAT adaptor fail to respond to Listeria monocytogenes infection

    Prinz, I., Kursar, M., Mittrücker, H-W., Aguado, E., Steinhoff, U., Kaufmann, S. H. E. & Malissen, B., 01.07.2005, In: INT IMMUNOL. 17, 7, p. 951-7 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Decreased frequency of intrathymic regulatory T cells in patients with myasthenia-associated thymoma

    Luther, C., Poeschel, S., Varga, M., Melms, A. & Tolosa, E., 01.07.2005, In: J NEUROIMMUNOL. 164, 1-2, p. 124-8 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection

    Kursar, M., Höpken, U. E., Koch, M., Köhler, A., Lipp, M., Kaufmann, S. H. E. & Mittrücker, H-W., 02.05.2005, In: J EXP MED. 201, 9, p. 1447-57 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Targeted delivery of the ErbB2/HER2 tumor antigen to professional APCs results in effective antitumor immunity

    Rohrbach, F., Weth, R., Kursar, M., Sloots, A., Mittrücker, H-W. & Wels, W. S., 01.05.2005, In: J IMMUNOL. 174, 9, p. 5481-9 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences

    Kim, C., Gajendran, N., Mittrücker, H-W., Weiwad, M., Song, Y-H., Hurwitz, R., Wilmanns, M., Fischer, G. & Kaufmann, S. H. E., 29.03.2005, In: P NATL ACAD SCI USA. 102, 13, p. 4830-5 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins

    Krebs, C., Adriouch, S., Braasch, F., Koestner, W., Leiter, E. H., Seman, M., Lund, F. E., Oppenheimer, N., Haag, F. & Koch-Nolte, F., 15.03.2005, In: J IMMUNOL. 174, 6, p. 3298-305 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Alternatively spliced transcripts of the thymus-specific protease PRSS16 are differentially expressed in human thymus

    Luther, C., Wienhold, W., Oehlmann, R., Heinemann, M. K., Melms, A. & Tolosa, E., 01.02.2005, In: GENES IMMUN. 6, 1, p. 1-7 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Detecting and monitoring depression with a two-item questionnaire (PHQ-2).

    Löwe, B., Kroenke, K. & Gräfe, K., 2005, In: J PSYCHOSOM RES. 58, 2, p. 163-171 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. 2004
  39. Expression of selectin ligands on murine effector and IL-10-producing CD4+ T cells from non-infected and infected tissues

    Kretschmer, U., Bonhagen, K., Debes, G. F., Mittrücker, H-W., Erb, K. J., Liesenfeld, O., Zaiss, D., Kamradt, T., Syrbe, U. & Hamann, A., 01.11.2004, In: EUR J IMMUNOL. 34, 11, p. 3070-81 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. Identification of Salmonella typhimurium genes responsible for interference with peptide presentation on MHC class I molecules: Deltayej Salmonella mutants induce superior CD8+ T-cell responses

    Qimron, U., Madar, N., Mittrücker, H-W., Zilka, A., Yosef, I., Bloushtain, N., Kaufmann, S. H. E., Rosenshine, I., Apte, R. N. & Porgador, A., 01.11.2004, In: CELL MICROBIOL. 6, 11, p. 1057-70 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Enhanced TCR-induced apoptosis in interferon regulatory factor 4-deficient CD4(+) Th cells

    Lohoff, M., Mittrücker, H-W., Brüstle, A., Sommer, F., Casper, B., Huber, M., Ferrick, D. A., Duncan, G. S. & Mak, T. W., 19.07.2004, In: J EXP MED. 200, 2, p. 247-53 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. Vaccination against tuberculosis: current status and future promise

    Kaufmann, S. H. & Mittrücker, H-W., 01.06.2004, In: SEMIN RESP CRIT CARE. 25, 3, p. 345-52 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes

    Burster, T., Beck, A., Tolosa, E., Marin-Esteban, V., Rötzschke, O., Falk, K., Lautwein, A., Reich, M., Brandenburg, J., Schwarz, G., Wiendl, H., Melms, A., Lehmann, R., Stevanovic, S., Kalbacher, H. & Driessen, C., 01.05.2004, In: J IMMUNOL. 172, 9, p. 5495-503 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Different patterns of nicotinic acetylcholine receptor subunit transcription in human thymus

    Bruno, R., Sabater, L., Tolosa, E., Sospedra, M., Ferrer-Francesch, X., Coll, J., Foz, M., Melms, A. & Pujol-Borrell, R., 01.04.2004, In: J NEUROIMMUNOL. 149, 1-2, p. 147-59 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Depletion of CD4+ T cells during immunization with nonviable Listeria monocytogenes causes enhanced CD8+ T cell-mediated protection against listeriosis

    Kursar, M., Köhler, A., Kaufmann, S. H. E. & Mittrücker, H-W., 01.03.2004, In: J IMMUNOL. 172, 5, p. 3167-72 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. Protective T cell response against intracellular pathogens in the absence of Toll-like receptor signaling via myeloid differentiation factor 88

    Kursar, M., Mittrücker, H-W., Koch, M., Köhler, A., Herma, M. & Kaufmann, S. H. E., 01.03.2004, In: INT IMMUNOL. 16, 3, p. 415-21 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Mini-review: regulatory T cells and infection: suppression revisited

    Mittrücker, H-W. & Kaufmann, S. H. E., 01.02.2004, In: EUR J IMMUNOL. 34, 2, p. 306-12 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Antigen-specific CD8+ T cell responses in intestinal tissues during murine listeriosis

    Kursar, M., Bonhagen, K., Köhler, A., Kamradt, T., Kaufmann, S. H. E., Mittrücker, H. W. & Mittrücker, H-W., 01.01.2004, In: MICROBES INFECT. 6, 1, p. 8-16 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Anxiety and depression in patients with pulmonary hypertension.

    Löwe, B., Gräfe, K., Ufer, C., Kroenke, K., Grünig, E., Herzog, W. & Borst, M. M., 2004, In: PSYCHOSOM MED. 66, 6, p. 831-836 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. Comparative validity of three screening questionnaires for DSM-IV depressive disorders and physicians' diagnoses.

    Löwe, B., Spitzer, R. L., Gräfe, K., Kroenke, K., Quenter, A., Zipfel, S., Buchholz, C., Witte, S. & Herzog, W., 2004, In: J AFFECT DISORDERS. 78, 2, p. 131-140 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Diagnosing ICD-10 depressive episodes: superior criterion validity of the Patient Health Questionnaire.

    Löwe, B., Gräfe, K., Zipfel, S., Witte, S., Loerch, B. & Herzog, W., 2004, In: PSYCHOTHER PSYCHOSOM. 73, 6, p. 386-390 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Measuring depression outcome with a brief self-report instrument: sensitivity to change of the Patient Health Questionnaire (PHQ-9).

    Löwe, B., Kroenke, K., Herzog, W. & Gräfe, K., 2004, In: J AFFECT DISORDERS. 81, 1, p. 61-66 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. 2003
  54. Expression of the B7-related molecule ICOSL by human glioma cells in vitro and in vivo

    Schreiner, B., Wischhusen, J., Mitsdoerffer, M., Schneider, D., Bornemann, A., Melms, A., Tolosa, E., Weller, M. & Wiendl, H., 01.12.2003, In: GLIA. 44, 3, p. 296-301 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor

    Seman, M., Adriouch, S., Scheuplein, F., Krebs, C., Freese, D., Glowacki, G., Deterre, P., Haag, F. & Koch-Nolte, F., 10.2003, In: IMMUNITY. 19, 4, p. 571-82 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review