Institute of Anatomy and Experimental Morphology
Publications
- 2013
Genomic deletion of MAP3K7 at 6q12-22 is associated with early PSA recurrence in prostate cancer and absence of TMPRSS2:ERG fusions
Kluth, M., Hesse, J., Heinl, A., Krohn, A., Steurer, S., Sirma, H., Simon, R., Mayer, P-S., Schumacher, U., Grupp, K., Izbicki, J. R., Pantel, K., Dikomey, E., Korbel, J. O., Plass, C., Sauter, G., Schlomm, T. & Minner, S., 01.07.2013, In: MODERN PATHOL. 26, 7, p. 975-83 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TCTEX1D4, a novel protein phosphatase 1 interactor: connecting the phosphatase to the microtubule network
Korrodi-Gregório, L., Vieira, S. I., Esteves, S. L. C., Silva, J. V., Freitas, M. J., Brauns, A-K., Luers, G., Abrantes, J., Esteves, P. J., da Cruz E Silva, O. A. B., Fardilha, M. & da Cruz E Silva, E. F., 15.05.2013, In: BIOL OPEN. 2, 5, p. 453-65 13 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy
Paavola, J., Schliffke, S., Rossetti, S., Kuo, I. Y-T., Yuan, S., Sun, Z., Harris, P. C., Torres, V. E. & Ehrlich, B. E., 01.05.2013, In: J MOL CELL CARDIOL. 58, p. 199-208 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selectin binding is essential for peritoneal carcinomatosis in a xenograft model of human pancreatic adenocarcinoma in pfp--/rag2-- mice
Gebauer, F., Wicklein, D., Stübke, K., Nehmann, N., Schmidt, A., Salamon, J., Peldschus, K., Nentwich, M. F., Adam, G., Tolstonog, G., Bockhorn, M., Izbicki, J. R., Wagener, C. & Schumacher, U., 01.05.2013, In: GUT. 62, 5, p. 741-50 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Parthenogenetic stem cells for tissue-engineered heart repair
Didié, M., Christalla, P., Rubart, M., Muppala, V., Döker, S., Unsöld, B., El-Armouche, A., Rau, T., Eschenhagen, T., Schwoerer, A. P., Ehmke, H., Schumacher, U., Fuchs, S., Lange, C., Becker, A., Tao, W., Scherschel, J. A., Soonpaa, M. H., Yang, T., Lin, Q., Zenke, M., Han, D-W., Schöler, H. R., Rudolph, C., Steinemann, D., Schlegelberger, B., Kattman, S., Witty, A., Keller, G., Field, L. J. & Zimmermann, W-H., 01.03.2013, In: J CLIN INVEST. 123, 3, p. 1285-98 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Comparison of the direct effects of human adipose- and bone-marrow-derived stem cells on postischemic cardiomyoblasts in an in vitro simulated ischemia-reperfusion model
Szepes, M., Benkő, Z., Cselenyák, A., Kompisch, K. M., Schumacher, U., Lacza, Z. & Kiss, L., 01.01.2013, In: Stem Cells Int. 2013, p. 178346Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model
Wicklein, D., Schmidt, A., Labitzky, V., Ullrich, S., Valent, P. & Schumacher, U., 01.01.2013, In: PLOS ONE. 8, 7, p. e70139Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Epithelial-mesenchymal Transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds
Samatov, T. R., Tonevitsky, A. G. & Schumacher, U., 01.01.2013, In: MOL CANCER. 12, 1, p. 107Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice
Hauber, I., Hofmann-Sieber, H., Chemnitz, J., Dubrau, D., Chusainow, J., Stucka, R., Hartjen, P., Schambach, A., Ziegler, P., Hackmann, K., Schröck, E., Schumacher, U., Lindner, C., Grundhoff, A., Baum, C., Manz, M. G., Buchholz, F. & Hauber, J., 01.01.2013, In: PLOS PATHOG. 9, 9, p. e1003587Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-throughput identification of reference genes for research and clinical RT-qPCR analysis of breast cancer samples
Maltseva, D. V., Khaustova, N. A., Fedotov, N. N., Matveeva, E. O., Lebedev, A. E., Shkurnikov, M. U., Galatenko, V. V., Schumacher, U. & Tonevitsky, A. G., 01.01.2013, In: J Clin Bioinforma. 3, 1, p. 13Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased expression of complement regulators CD55 and CD59 on peripheral blood cells in patients with EAHEC O104:H4 infection
Dammermann, W., Schipper, P., Ullrich, S., Zimmermann-Fraedrich, K., Schulze Zur Wiesch, J., Fründt, T., Tiegs, G., Lohse, A. & Lüth, S., 01.01.2013, In: PLOS ONE. 8, 9, p. e74880Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Anatomische und funktionelle Grundlagen
Lüers, G. H., 2013, Praxisbuch Sexuelle Störungen: Sexuelle Gesundheit, Sexualmedizinn, Psychotherapie sexueller Störungen. Briken, P. & Berner, M. (eds.). 1 ed. Stuttgart: Georg Thieme Verlag KG, p. 25-34 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Education › peer-review
Die Mistellektine als wirksamkeitsmitbestimmende Bestandteile von Mistelextrakten
Pfüller, U. & Schumacher, U., 2013, Die Mistel in der Tumortherapie 3 - Aktueller Stand der Forschung und klinische Anwendung. Scheer, R., Alban, S., Becker, H., Blaschek, W., Kemper, F. H., Kreis, W., Matthes, H., Schilcher, H. & Stange, R. (eds.). 1 ed. Essen: KVC Verlag, p. 3 - 12 10 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Expression of the coxsackie adenovirus receptor in neuroendocrine lung cancers and its implications for oncolytic adenoviral infection.
Wunder, T., Schmid, K., Wicklein, D., Groitl, P., Dobner, T., Lange, T., Anders, M. & Schumacher, U., 2013, In: CANCER GENE THER. 20, 1, p. 25-32 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Influence of L1-CAM expression of breast cancer cells on adhesion to endothelial cells.
Dippel, V., Milde-Langosch, K., Wicklein, D., Schumacher, U., Altevogt, P., Oliveira-Ferrer, L., Jänicke, F. & Schröder, C., 2013, In: J CANCER RES CLIN. 139, 1, p. 107-121 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Interaction of magnetically labeled multipotent mesenchymal stromal cells and E-and P-selectins monitored by magnetic resonance imaging in mice
Peldschus, K., Salamon, J., Wicklein, D., Lange, C., Ittrich, H., Adam, G. & Schumacher, U., 2013, In: MOL IMAGING. 12, 2, p. 100-10 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Low-grade and high-grade mammary carcinomas in WAP-T transgenic mice are independent entities distinguished by Met expression.
Otto, B., Gruner, K., Heinlein, C., Wegwitz, F., Nollau, P., Ylstra, B., Pantel, K., Schumacher, U., Baumbusch, L. O., Martin-Subero, J. I., Siebert, R., Wagener, C., Streichert, T., Deppert, W. & Tolstonog, G. V., 2013, In: INT J CANCER. 132, 6, p. 1300-1310 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mistellektine sind die wirksamkeitsbestimmenden Inhaltsstoffe des normierten Mistelextrakts PS76A2 (Lektinol®)
Mengs, U., Pfüller, U. & Blaschek, W., 2013, Die Mistel in der Tumortherapie 3: Aktueller Stand der Forschung und klinische Anwendung. Scheer, R., Alban, S., Becker, H., Blaschek, W., Kemper, F. H., Kreis, W., Matthes, H., Schilcher, H. & Stange, R. (eds.). 1 ed. KVC Verlag, p. 13-24 12 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
Prognostic relevance of ubiquitin C-terminal hydrolase L1 (UCH-L1) mRNA and protein expression in breast cancer patients
Schröder, C., Milde-Langosch, K., Gebauer, F., Schmid, K., Müller, V., Wirtz, R. M., Meyer-Schwesinger, C., Schluter, H., Sauter, G. & Schumacher, U., 2013, In: J CANCER RES CLIN. 139, p. 1745-1755 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selektive Inaktivierung der B-Untereinheit der Mistellektine und anderer RIP-II-Lektine in ionischen Flüssigkeiten
Pfüller, U. & Pfüller, K., 2013, Die Mistel in der Tumortherapie 3 - Aktueller Stand der Forschung und klinische Anwendung. Scheer, R., Alban, S., Becker, H., Blaschek, W., Kemper, F. H., Kreis, W., Matthes, H., Schilcher, H. & Stange, R. (eds.). 1 ed. KVC Verlag, p. 37-44 8 p.Research output: SCORING: Contribution to book/anthology › SCORING: Contribution to collected editions/anthologies › Research › peer-review
- 2012
Coxsackie adenovirus receptor expression in carcinomas of the head and neck
Wunder, T., Schumacher, U. & Friedrich, R. E., 01.03.2012, In: ANTICANCER RES. 32, 3, p. 1057-62 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A dynamic model for tumour growth and metastasis formation.
Haustein, V. & Schumacher, U., 2012, In: J Clin Bioinforma. 2, 1, p. 11 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Are metastases from metastases clinical relevant? Computer modelling of cancer spread in a case of hepatocellular carcinoma.
Bethge, A., Schumacher, U., Wree, A. & Wedemann, G., 2012, In: PLOS ONE. 7, 4, p. 35689 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A simple and widely applicable method to 59Fe-radiolabel monodisperse superparamagnetic iron oxide nanoparticles for in vivo quantification studies.
Freund, B., Tromsdorf, U. I., Bruns, O. T., Heine, M., Giemsa, A., Bartelt, A., Salmen, S. C., Raabe, N., Heeren, J., Ittrich, H., Reimer, R., Hohenberg, H., Schumacher, U., Weller, H. & Nielsen, P., 2012, In: ACS NANO. 6, 8, p. 7318-7325 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cartilage destruction in granulomatosis with polyangiitis (Wegener's granulomatosis) is mediated by human fibroblasts after transplantation into immunodeficient mice.
Kesel, N., Köhler, D., Herich, L., Laudien, M., Holl-Ulrich, K., Jüngel, A., Neidhart, M., Gay, S., Gay, R. E., Csernok, E., Lamprecht, P., Gross, W. L., Schumacher, U. & Ullrich, S., 2012, In: AM J PATHOL. 180, 5, p. 2144-2155 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Combined targeting of AKT and mTOR synergistically inhibits proliferation of hepatocellular carcinoma cells.
Grabinski, N., Ewald, F., Hofmann, B. T., Staufer, K., Schumacher, U., Nashan, B. & Jücker, M., 2012, In: MOL CANCER. 11, p. 85Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cre-mediated stress affects sirtuin expression levels, peroxisome biogenesis and metabolism, antioxidant and proinflammatory signaling pathways.
Xiao, Y., Karnati, S., Qian, G., Nenicu, A., Fan, W., Tchatalbachev, S., Höland, A., Hossain, H., Guillou, F., Lüers, G. & Baumgart-Vogt, E., 2012, In: PLOS ONE. 7, 7, p. 41097 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Derivation of functional ventricular cardiomyocytes using endogenous promoter sequence from murine embryonic stem cells.
Lee, M. Y., Sun, B., Schliffke, S., Yue, Z., Ye, M., Paavola, J., Bozkulak, E. C., Amos, P. J., Ren, Y., Ju, R., Jung, Y. W., Ge, X., Yue, L., Ehrlich, B. E. & Qyang, Y., 2012, In: STEM CELL RES. 8, 1, p. 49-57 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Detection of activated leukocyte cell adhesion molecule in the serum of breast cancer patients and implications for prognosis.
Witzel, I., Schröder, C., Müller, V., Zander, H., Tachezy, M., Henningsen, M., Jänicke, F. & Milde-Langosch, K., 2012, In: ONCOLOGY-BASEL. 82, 6, p. 305-312 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.
Keller, J., Brink, S., Busse, B., Schilling, A., Schinke, T., Amling, M. & Lange, T., 2012, In: PLOS ONE. 7, 10, p. 46757 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes.
Heine, M., Freund, B., Nielsen, P., Jung, C., Reimer, R., Hohenberg, H., Zangemeister-Wittke, U., Wester, H-J., Lüers, G. & Schumacher, U., 2012, In: PLOS ONE. 7, 5, p. 36258 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Human prostate cancer in a clinically relevant xenograft mouse model: identification of β(1,6)-branched oligosaccharides as a marker of tumor progression.
Lange, T., Ullrich, S., Müller, I., Nentwich, M., Stübke, K., Feldhaus, S., Knies, C., Hellwinkel, O., Vessella, R. L., Abramjuk, C., Anders, M., Schröder-Schwarz, J., Schlomm, T., Huland, H., Sauter, G. & Schumacher, U., 2012, In: CLIN CANCER RES. 18, 5, p. 1364-1373 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Hyaluronan export through plasma membranes depends on concurrent K+ efflux by K(ir) channels.
Hagenfeld, D., Borkenhagen, B., Schulz, T., Schillers, H., Schumacher, U. & Prehm, P., 2012, In: PLOS ONE. 7, 6, p. 39096 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells.
Glassmeier, G., Hempel, K., Wulfsen, I., Bauer, C. K., Schumacher, U. & Schwarz, J., 2012, In: PFLUG ARCH EUR J PHY. 463, 2, p. 365-376 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inhibition of the bacterial lectins of Pseudomonas aeruginosa with monosaccharides and peptides.
Gustke, H., Kleene, R., Loers, G., Nehmann, N., Jaehne, M., Bartels, K-M., Jaeger, K-E., Schachner, M. & Schumacher, U., 2012, In: EUR J CLIN MICROBIOL. 31, 2, p. 207-215 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
MDR-1-overexpression in HT 29 colon cancer cells grown in SCID mice.
Schumacher, U., Nehmann, N., Adam, E., Mukthar, D., Slotki, I. N., Horny, H-P., Flens, M. J., Schlegelberger, B. & Steinemann, D., 2012, In: ACTA HISTOCHEM. 114, 6, p. 594-602 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nilotinib and imatinib are comparably effective in reducing growth of human eosinophil leukemia cells in a newly established xenograft model.
Wicklein, D., Ramos Leal, N., Salamon, J. M., Thamer, M., Herrmann, H., Valent, P., Schumacher, U. & Ullrich, S., 2012, In: PLOS ONE. 7, 2, p. 30567 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
p65-Dependent production of interleukin-1β by osteolytic prostate cancer cells causes an induction of chemokine expression in osteoblasts.
Schulze, J., Riecken, K., Baranowsky, A., Streichert, T., Lange, T., Spiro, A. S., Albers, J., Seitz, S., Zustin, J., Amling, M., Fehse, B. & Schinke, T., 2012, In: CANCER LETT. 317, 1, p. 106-113 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulation of cell volume by glycosaminoglycans.
Joerges, J., Schulz, T., Wegner, J., Schumacher, U. & Prehm, P., 2012, In: J CELL BIOCHEM. 113, 1, p. 340-348 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
RNAi technology to block the expression of molecules relevant to metastasis: the cell adhesion molecule CEACAM1 as an instructive example.
Wicklein, D., 2012, In: Methods Mol Biol. 878, p. 241-250Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Selectin-deficiency reduces the number of spontaneous metastases in a xenograft model of human breast cancer.
Stübke, K., Wicklein, D., Herich, L., Schumacher, U. & Nehmann, N., 2012, In: CANCER LETT. 321, 1, p. 89-99 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Synergistic effects of erlotinib and everolimus on bronchial carcinoids and large-cell neuroendocrine carcinomas with activated EGFR/AKT/mTOR pathway.
Bago-Horvath, Z., Sieghart, W., Grusch, M., Lackner, A., Hayden, H., Pirker, C., Komina, O., Węsierska-Gądek, J., Haitel, A., Filipits, M., Berger, W. & Schmid, K., 2012, In: NEUROENDOCRINOLOGY. 96, 3, p. 228-237 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tailor-made quantum dot and iron oxide based contrast agents for in vitro and in vivo tumor imaging.
Pöselt, E., Schmidtke, C., Fischer, S., Peldschus, K., Salamon, J. M., Kloust, H., Tran, H., Pietsch, A., Heine, M., Adam, G., Schumacher, U., Wagener, C., Förster, S. & Weller, H., 2012, In: ACS NANO. 6, 4, p. 3346-3355 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Tetrastarch sustains pulmonary microvascular perfusion and gas exchange during systemic inflammation.
Heckel, K., Winkelmann, B., Strunden, M. S., Basedow, A., Schuster, A., Schumacher, U., Kiefmann, R., Reuter, D. & Goetz, A. E., 2012, In: CRIT CARE MED. 40, 2, p. 518-531 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The interaction between CD44 on tumour cells and hyaluronan under physiologic flow conditions: implications for metastasis formation.
Richter, U., Wicklein, D., Geleff, S. & Schumacher, U., 2012, In: HISTOCHEM CELL BIOL. 137, 5, p. 687-695 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Transient complex interactions of mammalian peroxisomes without exchange of matrix or membrane marker proteins.
Bonekamp, N. A., Sampaio, P., Abreu, D., Lüers, G. H. & Schrader, M., 2012, In: TRAFFIC. 13, 7, p. 960-978 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
XMRV induces cell migration, cytokine expression and tumor angiogenesis: are 22Rv1 cells a suitable prostate cancer model?
Stieler, K., Schumacher, U., Horst, A. & Fischer, N., 2012, In: PLOS ONE. 7, 7, p. 42321 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2011
3D fluoroscopic navigated reaming of the glenoid for total shoulder arthroplasty (TSA).
Briem, D., Rücker, A. H., Neumann, J., Gebauer, M., Kendoff, D., Gehrke, T., Lehmann, W., Schumacher, U., Rueger, J. M. & Großterlinden, L. G., 2011, In: COMPUT AIDED SURG. 16, 2, p. 93-99 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Adhesion of small cell lung cancer cells to E- and P-selectin under physiological flow conditions: implications for metastasis formation.
Richter, U., Schröder, C., Wicklein, D., Lange, T., Geleff, S., Dippel, V., Schumacher, U. & Klutmann, S., 2011, In: HISTOCHEM CELL BIOL. 135, 5, p. 499-512 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Brachyury expression predicts poor prognosis at early stages of colorectal cancer.
Kilic, N., Feldhaus, S., Kilic, E., Tennstedt, P., Wicklein, D., Wasielewski, R. V., Viebahn, C., Kreipe, H. & Schumacher, U., 2011, In: EUR J CANCER. 47, 7, p. 1080-1085 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review