III. Department of Medicine

Publications

  1. 2005
  2. CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency

    Grunkemeyer, J. A., Kwoh, C., Huber, T. B. & Shaw, A. S., 19.08.2005, In: J BIOL CHEM. 280, 33, p. 29677-81 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Cytosolic Cl- ions in the regulation of secretory and endocytotic activity in melanotrophs from mouse pituitary tissue slices

    Turner, J-E., Sedej, S., Rupnik, M. & Turner, J. E., 15.07.2005, In: J PHYSIOL-LONDON. 566, Pt 2, p. 443-53 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. The slit diaphragm: a signaling platform to regulate podocyte function

    Huber, T. B. & Benzing, T., 05.2005, In: CURR OPIN NEPHROL HY. 14, 3, p. 211-6 6 p.

    Research output: SCORING: Contribution to journalSCORING: Review articleResearch

  5. CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins

    Krebs, C., Adriouch, S., Braasch, F., Koestner, W., Leiter, E. H., Seman, M., Lund, F. E., Oppenheimer, N., Haag, F. & Koch-Nolte, F., 15.03.2005, In: J IMMUNOL. 174, 6, p. 3298-305 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation

    Köttgen, M., Benzing, T., Simmen, T., Tauber, R., Buchholz, B., Feliciangeli, S., Huber, T. B., Schermer, B., Kramer-Zucker, A., Höpker, K., Simmen, K. C., Tschucke, C. C., Sandford, R., Kim, E., Thomas, G. & Walz, G., 23.02.2005, In: EMBO J. 24, 4, p. 705-16 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. Angiotensin II down-regulates the SR-BI HDL receptor in proximal tubular cells.

    Wolf, G., Wenzel, U., Jablonski, K., Brundert, M. & Rinninger, F., 2005, In: NEPHROL DIAL TRANSPL. 20, 6, p. 1222-1227 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  8. Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase.

    Merkel, M., Loeffler, B., Kluger, M. A., Fabig, N., Geppert, G., Pennacchio, L. A., Laatsch, A. & Heeren, J., 2005, In: J BIOL CHEM. 280, 22, p. 21553-21560 22.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. A polymorphism in the apolipoprotein A5 gene is associated with weight loss after short-term diet.

    Aberle, J., Evans, D., Beil, F. U. & Seedorf, U., 2005, In: CLIN GENET. 68, 2, p. 152-154 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection.

    Steinmetz, O. M., Panzer, U., Kneissler, U., Harendza, S., Lipp, M., Helmchen, U. & Stahl, R. A. K., 2005, In: KIDNEY INT. 67, 4, p. 1616-1621 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Give me A5 for lipoprotein hydrolysis!

    Merkel, M. & Heeren, J., 2005, In: J CLIN INVEST. 115, 10, p. 2694-2696 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Knockdown of hepatic ABCA1 by RNA interference decreases plasma HDL cholesterol levels and influences postprandial lipemia in mice.

    Ragozin, S., Niemeier, A., Laatsch, A., Loeffler, B., Merkel, M., Beisiegel, U. & Heeren, J., 2005, In: ARTERIOSCL THROM VAS. 25, 7, p. 1433-1438 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Polymorphisms in the apolipoprotein A5 (APOA5) gene and type III hyperlipidemia.

    Evans, D., Seedorf, U. & Beil, F. U., 2005, In: CLIN GENET. 68, 4, p. 369-372 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. Scavenger receptor class B type I mediates the selective uptake of high-density lipoprotein-associated cholesteryl ester by the liver in mice.

    Brundert, M., Ewert, A., Heeren, J., Behrendt, B., Ramakrishnan, R., Greten, H., Merkel, M. & Rinninger, F., 2005, In: ARTERIOSCL THROM VAS. 25, 1, p. 143-148 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. The chemokine receptor 5 Delta32 mutation is associated with increased renal survival in patients with IgA nephropathy.

    Panzer, U., Schneider, A., Steinmetz, O. M., Wenzel, U., Barth, P., Reinking, R., Becker, J. U., Harendza, S., Zahner, G., Fischereder, M., Krämer, B. K., Krämer, B. H., Schlöndorff, D., Ostendorf, T., Floege, J., Helmchen, U. & Stahl, R. A. K., 2005, In: KIDNEY INT. 67, 1, p. 75-81 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. 2004
  17. Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney

    Meyer, T. N., Meyer-Schwesinger, C., Bush, K. T., Stuart, R. O., Rose, D. W., Shah, M. M., Vaughn, D. A., Steer, D. L. & Nigam, S. K., 01.11.2004, In: DEV BIOL. 275, 1, p. 44-67 24 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Vitamin B6 modulates glucocorticoid-dependent gene transcription in a promoter- and cell type-specific manner

    Bamberger, C. M., Else, T., Ellebrecht, I., Milde-Langosch, K., Pankoke, D., Beil, F. U. & Bamberger, A-M., 11.2004, In: EXP CLIN ENDOCR DIAB. 112, 10, p. 595-600 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney

    Steer, D. L., Shah, M. M., Bush, K. T., Stuart, R. O., Sampogna, R. V., Meyer, T. N., Meyer-Schwesinger, C., Bai, X., Esko, J. D. & Nigam, S. K., 15.08.2004, In: DEV BIOL. 272, 2, p. 310-27 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud

    Bush, K. T., Sakurai, H., Steer, D. L., Leonard, M. O., Sampogna, R. V., Meyer, T. N., Meyer-Schwesinger, C., Qiao, J. & Nigam, S. K., 15.02.2004, In: DEV BIOL. 266, 2, p. 285-98 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. Angiotensin II and cell cycle regulation.

    Wolf, G. & Wenzel, U., 2004, In: HYPERTENSION. 43, 4, p. 693-698 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. Decreased interferon-gamma response in respiratory syncytial virus compared to other respiratory viral infections in infants.

    Aberle, J., Aberle, S. W., Rebhandl, W., Pracher, E., Kundi, M. & Popow-Kraupp, T., 2004, In: CLIN EXP IMMUNOL. 137, 1, p. 146-150 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  23. Disseminated Mycobacterium haemophilum infection as initial manifestation of AIDS.

    Stürenburg, E. E., Horstkotte, M. A., Aberle, J., Meyer, K., Richter, E., Laufs, R. & Sobottka, I., 2004, In: TUBERCULOSIS. 84, 6, p. 341-345 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Mice expressing only covalent dimeric heparin binding-deficient lipoprotein lipase: muscles inefficiently secrete dimeric enzyme.

    Lutz, E. P., Kako, Y., Yagyu, H., Heeren, J., Marks, S., Wright, T., Melford, K., Ben-Zeev, O., Radner, H., Merkel, M., Bensadoun, A., Wong, H. & Goldberg, I. J., 2004, In: J BIOL CHEM. 279, 1, p. 238-244 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Severe myelitis following infection with Campylobacter enteritis.

    Aberle, J., Kluwe, J., Pawlas, F., Stellbrink, H. J. & Greten, H., 2004, In: EUR J CLIN MICROBIOL. 23, 2, p. 134-135 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Synovial chondromatosis of the hip: a case report and clinicopathologic study.

    Gille, J., Krueger, S., Aberle, J., Boehm, S., Ince, A. & Loehr, J. F., 2004, In: ACTA ORTHOP BELG. 70, 2, p. 182-188 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. 2003
  28. Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains

    Huber, T. B., Simons, M., Hartleben, B., Sernetz, L., Schmidts, M., Gundlach, E., Saleem, M. A., Walz, G. & Benzing, T., 15.12.2003, In: HUM MOL GENET. 12, 24, p. 3397-405 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  29. Galpha12 regulates epithelial cell junctions through Src tyrosine kinases

    Meyer, T. N., Hunt, J., Meyer-Schwesinger, C. & Denker, B. M., 01.11.2003, In: AM J PHYSIOL-CELL PH. 285, 5, p. C1281-93

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor

    Seman, M., Adriouch, S., Scheuplein, F., Krebs, C., Freese, D., Glowacki, G., Deterre, P., Haag, F. & Koch-Nolte, F., 10.2003, In: IMMUNITY. 19, 4, p. 571-82 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Molekulare Genetik in der Nephrologie. Von der Genetik des familiären nephrotischen Syndroms zum Verständnis des glomerulären Filters der Niere

    Huber, T. B. & Benzing, T., 08.2003, In: THER UMSCH. 60, 8, p. 435-7 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling

    Huber, T. B., Hartleben, B., Kim, J., Schmidts, M., Schermer, B., Keil, A., Egger, L., Lecha, R. L., Borner, C., Pavenstädt, H., Shaw, A. S., Walz, G. & Benzing, T., 07.2003, In: MOL CELL BIOL. 23, 14, p. 4917-28 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1

    Huber, T. B., Schmidts, M., Gerke, P., Schermer, B., Zahn, A., Hartleben, B., Sellin, L., Walz, G. & Benzing, T., 11.04.2003, In: J BIOL CHEM. 278, 15, p. 13417-21 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1

    Gerke, P., Huber, T. B., Sellin, L., Benzing, T. & Walz, G., 04.2003, In: J AM SOC NEPHROL. 14, 4, p. 918-26 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. Stra13, a prostaglandin E2-induced gene, regulates the cellular redox state of podocytes

    Bek, M. J., Wahle, S., Müller, B., Benzing, T., Huber, T. B., Kretzler, M., Cohen, C., Busse-Grawitz, A. & Pavenstädt, H., 04.2003, In: FASEB J. 17, 6, p. 682-4 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Flow cytometric and immunoblot assays for cell surface ADP-ribosylation using a monoclonal antibody specific for ethenoadenosine

    Krebs, C., Koestner, W., Nissen, M., Welge, V., Parusel, I., Malavasi, F., Leiter, E. H., Santella, R. M., Haag, F. & Koch-Nolte, F., 01.03.2003, In: ANAL BIOCHEM. 314, 1, p. 108-15 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. NEPH1 defines a novel family of podocin interacting proteins

    Sellin, L., Huber, T. B., Gerke, P., Quack, I., Pavenstädt, H. & Walz, G., 01.2003, In: FASEB J. 17, 1, p. 115-7 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. A young woman with persistent hypoglycemia, rhabdomyolysis, and coma: recognizing fatty acid oxidation defects in adults.

    Kluge, S., Kühnelt, P., Block, A., Merkel, M., Gocht, A., Lukacs, Z., Kohlschütter, A. & Kreymann, G., 2003, In: CRIT CARE MED. 31, 4, p. 1273-1276 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Beneficial and adverse renal and vascular effects of the vasopeptidase inhibitor omapatrilat in renovascular hypertensive rats.

    Wenzel, U., Wolf, G., Jacob, I., Schwegler, C., Qasqas, A., Amann, K., Helmchen, U. & Stahl, R. A. K., 2003, In: NEPHROL DIAL TRANSPL. 18, 10, p. 2005-2013 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. [L-carnitine and lipid lowering]

    Merkel, M. & Greten, H., 2003, In: DEUT MED WOCHENSCHR. 128, 34-35, p. 1792 34-35.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  41. Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy.

    Yagyu, H., Chen, G., Yokoyama, M., Hirata, K., Augustus, A., Kako, Y., Seo, T., Hu, Y., Lutz, E. P., Merkel, M., Bensadoun, A., Homma, S. & Goldberg, I. J., 2003, In: J CLIN INVEST. 111, 3, p. 419-426 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. [Lipoprotein lipase-mediated myopathy: implications for lipid metabolism and atherogenesis]

    Merkel, M., Radner, H. & Greten, H., 2003, In: MED KLIN-INTENSIVMED. 98, 12, p. 679-684 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. The association of the R219K polymorphism in the ATP-binding cassette transporter 1 ( ABCA1) gene with coronary heart disease and hyperlipidaemia.

    Evans, D. & Beil, F. U., 2003, In: J MOL MED. 81, 4, p. 264-270 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. The renin-angiotensin system and progression of renal disease: from hemodynamics to cell biology.

    Wolf, G., Butzmann, U. & Wenzel, U., 2003, In: NEPHRON PHYSIOL. 93, 1, p. 3-13 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. The single nucleotide polymorphism -1131T>C in the apolipoprotein A5 (APOA5) gene is associated with elevated triglycerides in patients with hyperlipidemia.

    Evans, D., Buchwald, A. & Beil, F. U., 2003, In: J MOL MED. 81, 10, p. 645-654 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. 2002
  47. A strategy for in vitro propagation of rat nephrons

    Steer, D. L., Bush, K. T., Meyer, T. N., Meyer-Schwesinger, C. & Nigam, S. K., 01.12.2002, In: KIDNEY INT. 62, 6, p. 1958-65 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Zonula occludens-1 is a scaffolding protein for signaling molecules. Galpha(12) directly binds to the Src homology 3 domain and regulates paracellular permeability in epithelial cells

    Meyer, T. N., Meyer-Schwesinger, C. & Denker, B. M., 12.07.2002, In: J BIOL CHEM. 277, 28, p. 24855-8 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. Expression of functional CCR and CXCR chemokine receptors in podocytes

    Huber, T. B., Reinhardt, H. C., Exner, M., Burger, J. A., Kerjaschki, D., Saleem, M. A. & Pavenstädt, H., 15.06.2002, In: J IMMUNOL. 168, 12, p. 6244-52 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  50. [48-year-old patient with right sided flank pain and hypertension of recent onset. Secondary hypertension caused by embolic renal infarcts due to dissecting renal artery aneurysms]

    Ameis, D., Knolinski, T., Guthoff, A., Wenzel, U. & Greten, H., 2002, In: INTERNIST. 43, 9, p. 1129-1132 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Angiotensin II activates nuclear transcription factor-kappaB through AT1 and AT2 receptors.

    Wolf, G., Wenzel, U., Burns, K. D., Harris, R. C., Stahl, R. A. K. & Thaiss, F., 2002, In: KIDNEY INT. 61, 6, p. 1986-1995 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Angiotensin II infusion ameliorates the early phase of a mesangioproliferative glomerulonephritis.

    Wenzel, U., Thaiss, F., Helmchen, U., Stahl, R. A. K. & Wolf, G., 2002, In: KIDNEY INT. 61, 3, p. 1020-1029 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. Angiotensin II's antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20.

    Wolf, G., Harendza, S., Schroeder, R., Wenzel, U., Zahner, G., Butzmann, U., Freeman, R. S. & Stahl, R. A. K., 2002, In: LAB INVEST. 82, 10, p. 1305-1317 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  54. Chronic anti-Thy-1 nephritis is aggravated in the nonclipped but not in the clipped kidney of Goldblatt hypertensive rats.

    Wenzel, U., Wolf, G., Jacob, I., Thaiss, F., Helmchen, U. & Stahl, R. A. K., 2002, In: KIDNEY INT. 61, 6, p. 2119-2131 6.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review