III. Department of Medicine
Publications
- 2005
CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency
Grunkemeyer, J. A., Kwoh, C., Huber, T. B. & Shaw, A. S., 19.08.2005, In: J BIOL CHEM. 280, 33, p. 29677-81 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cytosolic Cl- ions in the regulation of secretory and endocytotic activity in melanotrophs from mouse pituitary tissue slices
Turner, J-E., Sedej, S., Rupnik, M. & Turner, J. E., 15.07.2005, In: J PHYSIOL-LONDON. 566, Pt 2, p. 443-53 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The slit diaphragm: a signaling platform to regulate podocyte function
Huber, T. B. & Benzing, T., 05.2005, In: CURR OPIN NEPHROL HY. 14, 3, p. 211-6 6 p.Research output: SCORING: Contribution to journal › SCORING: Review article › Research
CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins
Krebs, C., Adriouch, S., Braasch, F., Koestner, W., Leiter, E. H., Seman, M., Lund, F. E., Oppenheimer, N., Haag, F. & Koch-Nolte, F., 15.03.2005, In: J IMMUNOL. 174, 6, p. 3298-305 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation
Köttgen, M., Benzing, T., Simmen, T., Tauber, R., Buchholz, B., Feliciangeli, S., Huber, T. B., Schermer, B., Kramer-Zucker, A., Höpker, K., Simmen, K. C., Tschucke, C. C., Sandford, R., Kim, E., Thomas, G. & Walz, G., 23.02.2005, In: EMBO J. 24, 4, p. 705-16 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin II down-regulates the SR-BI HDL receptor in proximal tubular cells.
Wolf, G., Wenzel, U., Jablonski, K., Brundert, M. & Rinninger, F., 2005, In: NEPHROL DIAL TRANSPL. 20, 6, p. 1222-1227 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase.
Merkel, M., Loeffler, B., Kluger, M. A., Fabig, N., Geppert, G., Pennacchio, L. A., Laatsch, A. & Heeren, J., 2005, In: J BIOL CHEM. 280, 22, p. 21553-21560 22.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A polymorphism in the apolipoprotein A5 gene is associated with weight loss after short-term diet.
Aberle, J., Evans, D., Beil, F. U. & Seedorf, U., 2005, In: CLIN GENET. 68, 2, p. 152-154 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
BCA-1/CXCL13 expression is associated with CXCR5-positive B-cell cluster formation in acute renal transplant rejection.
Steinmetz, O. M., Panzer, U., Kneissler, U., Harendza, S., Lipp, M., Helmchen, U. & Stahl, R. A. K., 2005, In: KIDNEY INT. 67, 4, p. 1616-1621 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Give me A5 for lipoprotein hydrolysis!
Merkel, M. & Heeren, J., 2005, In: J CLIN INVEST. 115, 10, p. 2694-2696 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Knockdown of hepatic ABCA1 by RNA interference decreases plasma HDL cholesterol levels and influences postprandial lipemia in mice.
Ragozin, S., Niemeier, A., Laatsch, A., Loeffler, B., Merkel, M., Beisiegel, U. & Heeren, J., 2005, In: ARTERIOSCL THROM VAS. 25, 7, p. 1433-1438 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Polymorphisms in the apolipoprotein A5 (APOA5) gene and type III hyperlipidemia.
Evans, D., Seedorf, U. & Beil, F. U., 2005, In: CLIN GENET. 68, 4, p. 369-372 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Scavenger receptor class B type I mediates the selective uptake of high-density lipoprotein-associated cholesteryl ester by the liver in mice.
Brundert, M., Ewert, A., Heeren, J., Behrendt, B., Ramakrishnan, R., Greten, H., Merkel, M. & Rinninger, F., 2005, In: ARTERIOSCL THROM VAS. 25, 1, p. 143-148 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The chemokine receptor 5 Delta32 mutation is associated with increased renal survival in patients with IgA nephropathy.
Panzer, U., Schneider, A., Steinmetz, O. M., Wenzel, U., Barth, P., Reinking, R., Becker, J. U., Harendza, S., Zahner, G., Fischereder, M., Krämer, B. K., Krämer, B. H., Schlöndorff, D., Ostendorf, T., Floege, J., Helmchen, U. & Stahl, R. A. K., 2005, In: KIDNEY INT. 67, 1, p. 75-81 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2004
Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney
Meyer, T. N., Meyer-Schwesinger, C., Bush, K. T., Stuart, R. O., Rose, D. W., Shah, M. M., Vaughn, D. A., Steer, D. L. & Nigam, S. K., 01.11.2004, In: DEV BIOL. 275, 1, p. 44-67 24 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Vitamin B6 modulates glucocorticoid-dependent gene transcription in a promoter- and cell type-specific manner
Bamberger, C. M., Else, T., Ellebrecht, I., Milde-Langosch, K., Pankoke, D., Beil, F. U. & Bamberger, A-M., 11.2004, In: EXP CLIN ENDOCR DIAB. 112, 10, p. 595-600 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney
Steer, D. L., Shah, M. M., Bush, K. T., Stuart, R. O., Sampogna, R. V., Meyer, T. N., Meyer-Schwesinger, C., Bai, X., Esko, J. D. & Nigam, S. K., 15.08.2004, In: DEV BIOL. 272, 2, p. 310-27 18 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud
Bush, K. T., Sakurai, H., Steer, D. L., Leonard, M. O., Sampogna, R. V., Meyer, T. N., Meyer-Schwesinger, C., Qiao, J. & Nigam, S. K., 15.02.2004, In: DEV BIOL. 266, 2, p. 285-98 14 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin II and cell cycle regulation.
Wolf, G. & Wenzel, U., 2004, In: HYPERTENSION. 43, 4, p. 693-698 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decreased interferon-gamma response in respiratory syncytial virus compared to other respiratory viral infections in infants.
Aberle, J., Aberle, S. W., Rebhandl, W., Pracher, E., Kundi, M. & Popow-Kraupp, T., 2004, In: CLIN EXP IMMUNOL. 137, 1, p. 146-150 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Disseminated Mycobacterium haemophilum infection as initial manifestation of AIDS.
Stürenburg, E. E., Horstkotte, M. A., Aberle, J., Meyer, K., Richter, E., Laufs, R. & Sobottka, I., 2004, In: TUBERCULOSIS. 84, 6, p. 341-345 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Mice expressing only covalent dimeric heparin binding-deficient lipoprotein lipase: muscles inefficiently secrete dimeric enzyme.
Lutz, E. P., Kako, Y., Yagyu, H., Heeren, J., Marks, S., Wright, T., Melford, K., Ben-Zeev, O., Radner, H., Merkel, M., Bensadoun, A., Wong, H. & Goldberg, I. J., 2004, In: J BIOL CHEM. 279, 1, p. 238-244 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Severe myelitis following infection with Campylobacter enteritis.
Aberle, J., Kluwe, J., Pawlas, F., Stellbrink, H. J. & Greten, H., 2004, In: EUR J CLIN MICROBIOL. 23, 2, p. 134-135 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Synovial chondromatosis of the hip: a case report and clinicopathologic study.
Gille, J., Krueger, S., Aberle, J., Boehm, S., Ince, A. & Loehr, J. F., 2004, In: ACTA ORTHOP BELG. 70, 2, p. 182-188 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2003
Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains
Huber, T. B., Simons, M., Hartleben, B., Sernetz, L., Schmidts, M., Gundlach, E., Saleem, M. A., Walz, G. & Benzing, T., 15.12.2003, In: HUM MOL GENET. 12, 24, p. 3397-405 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Galpha12 regulates epithelial cell junctions through Src tyrosine kinases
Meyer, T. N., Hunt, J., Meyer-Schwesinger, C. & Denker, B. M., 01.11.2003, In: AM J PHYSIOL-CELL PH. 285, 5, p. C1281-93Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor
Seman, M., Adriouch, S., Scheuplein, F., Krebs, C., Freese, D., Glowacki, G., Deterre, P., Haag, F. & Koch-Nolte, F., 10.2003, In: IMMUNITY. 19, 4, p. 571-82 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Molekulare Genetik in der Nephrologie. Von der Genetik des familiären nephrotischen Syndroms zum Verständnis des glomerulären Filters der Niere
Huber, T. B. & Benzing, T., 08.2003, In: THER UMSCH. 60, 8, p. 435-7 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling
Huber, T. B., Hartleben, B., Kim, J., Schmidts, M., Schermer, B., Keil, A., Egger, L., Lecha, R. L., Borner, C., Pavenstädt, H., Shaw, A. S., Walz, G. & Benzing, T., 07.2003, In: MOL CELL BIOL. 23, 14, p. 4917-28 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1
Huber, T. B., Schmidts, M., Gerke, P., Schermer, B., Zahn, A., Hartleben, B., Sellin, L., Walz, G. & Benzing, T., 11.04.2003, In: J BIOL CHEM. 278, 15, p. 13417-21 5 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1
Gerke, P., Huber, T. B., Sellin, L., Benzing, T. & Walz, G., 04.2003, In: J AM SOC NEPHROL. 14, 4, p. 918-26 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Stra13, a prostaglandin E2-induced gene, regulates the cellular redox state of podocytes
Bek, M. J., Wahle, S., Müller, B., Benzing, T., Huber, T. B., Kretzler, M., Cohen, C., Busse-Grawitz, A. & Pavenstädt, H., 04.2003, In: FASEB J. 17, 6, p. 682-4 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Flow cytometric and immunoblot assays for cell surface ADP-ribosylation using a monoclonal antibody specific for ethenoadenosine
Krebs, C., Koestner, W., Nissen, M., Welge, V., Parusel, I., Malavasi, F., Leiter, E. H., Santella, R. M., Haag, F. & Koch-Nolte, F., 01.03.2003, In: ANAL BIOCHEM. 314, 1, p. 108-15 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
NEPH1 defines a novel family of podocin interacting proteins
Sellin, L., Huber, T. B., Gerke, P., Quack, I., Pavenstädt, H. & Walz, G., 01.2003, In: FASEB J. 17, 1, p. 115-7 3 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A young woman with persistent hypoglycemia, rhabdomyolysis, and coma: recognizing fatty acid oxidation defects in adults.
Kluge, S., Kühnelt, P., Block, A., Merkel, M., Gocht, A., Lukacs, Z., Kohlschütter, A. & Kreymann, G., 2003, In: CRIT CARE MED. 31, 4, p. 1273-1276 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Beneficial and adverse renal and vascular effects of the vasopeptidase inhibitor omapatrilat in renovascular hypertensive rats.
Wenzel, U., Wolf, G., Jacob, I., Schwegler, C., Qasqas, A., Amann, K., Helmchen, U. & Stahl, R. A. K., 2003, In: NEPHROL DIAL TRANSPL. 18, 10, p. 2005-2013 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[L-carnitine and lipid lowering]
Merkel, M. & Greten, H., 2003, In: DEUT MED WOCHENSCHR. 128, 34-35, p. 1792 34-35.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy.
Yagyu, H., Chen, G., Yokoyama, M., Hirata, K., Augustus, A., Kako, Y., Seo, T., Hu, Y., Lutz, E. P., Merkel, M., Bensadoun, A., Homma, S. & Goldberg, I. J., 2003, In: J CLIN INVEST. 111, 3, p. 419-426 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Lipoprotein lipase-mediated myopathy: implications for lipid metabolism and atherogenesis]
Merkel, M., Radner, H. & Greten, H., 2003, In: MED KLIN-INTENSIVMED. 98, 12, p. 679-684 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The association of the R219K polymorphism in the ATP-binding cassette transporter 1 ( ABCA1) gene with coronary heart disease and hyperlipidaemia.
Evans, D. & Beil, F. U., 2003, In: J MOL MED. 81, 4, p. 264-270 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The renin-angiotensin system and progression of renal disease: from hemodynamics to cell biology.
Wolf, G., Butzmann, U. & Wenzel, U., 2003, In: NEPHRON PHYSIOL. 93, 1, p. 3-13 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
The single nucleotide polymorphism -1131T>C in the apolipoprotein A5 (APOA5) gene is associated with elevated triglycerides in patients with hyperlipidemia.
Evans, D., Buchwald, A. & Beil, F. U., 2003, In: J MOL MED. 81, 10, p. 645-654 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2002
A strategy for in vitro propagation of rat nephrons
Steer, D. L., Bush, K. T., Meyer, T. N., Meyer-Schwesinger, C. & Nigam, S. K., 01.12.2002, In: KIDNEY INT. 62, 6, p. 1958-65 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Zonula occludens-1 is a scaffolding protein for signaling molecules. Galpha(12) directly binds to the Src homology 3 domain and regulates paracellular permeability in epithelial cells
Meyer, T. N., Meyer-Schwesinger, C. & Denker, B. M., 12.07.2002, In: J BIOL CHEM. 277, 28, p. 24855-8 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of functional CCR and CXCR chemokine receptors in podocytes
Huber, T. B., Reinhardt, H. C., Exner, M., Burger, J. A., Kerjaschki, D., Saleem, M. A. & Pavenstädt, H., 15.06.2002, In: J IMMUNOL. 168, 12, p. 6244-52 9 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[48-year-old patient with right sided flank pain and hypertension of recent onset. Secondary hypertension caused by embolic renal infarcts due to dissecting renal artery aneurysms]
Ameis, D., Knolinski, T., Guthoff, A., Wenzel, U. & Greten, H., 2002, In: INTERNIST. 43, 9, p. 1129-1132 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin II activates nuclear transcription factor-kappaB through AT1 and AT2 receptors.
Wolf, G., Wenzel, U., Burns, K. D., Harris, R. C., Stahl, R. A. K. & Thaiss, F., 2002, In: KIDNEY INT. 61, 6, p. 1986-1995 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin II infusion ameliorates the early phase of a mesangioproliferative glomerulonephritis.
Wenzel, U., Thaiss, F., Helmchen, U., Stahl, R. A. K. & Wolf, G., 2002, In: KIDNEY INT. 61, 3, p. 1020-1029 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin II's antiproliferative effects mediated through AT2-receptors depend on down-regulation of SM-20.
Wolf, G., Harendza, S., Schroeder, R., Wenzel, U., Zahner, G., Butzmann, U., Freeman, R. S. & Stahl, R. A. K., 2002, In: LAB INVEST. 82, 10, p. 1305-1317 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chronic anti-Thy-1 nephritis is aggravated in the nonclipped but not in the clipped kidney of Goldblatt hypertensive rats.
Wenzel, U., Wolf, G., Jacob, I., Thaiss, F., Helmchen, U. & Stahl, R. A. K., 2002, In: KIDNEY INT. 61, 6, p. 2119-2131 6.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review