III. Department of Medicine

Publications

  1. 2002
  2. Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B2 kinin receptors

    Fischer, K-G., Huber, T. B., Henger, A., Fink, E., Schwertfeger, E., Rump, L. C. & Pavenstädt, H., 2002, In: KIDNEY BLOOD PRESS R. 25, 6, p. 384-93 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  3. Endothelial-derived lipoprotein lipase is bound to postprandial triglyceride-rich lipoproteins and mediates their hepatic clearance in vivo.

    Heeren, J., Niemeier, A., Merkel, M. & Beisiegel, U., 2002, In: J MOL MED. 80, 9, p. 576-584 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  4. Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake.

    Merkel, M., Heeren, J., Dudeck, W., Rinninger, F., Radner, H., Breslow, J. L., Goldberg, I. J., Zechner, R. & Greten, H., 2002, In: J BIOL CHEM. 277, 9, p. 7405-7411 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  5. Lipoprotein lipase: genetics, lipid uptake, and regulation.

    Merkel, M., Eckel, R. H. & Goldberg, I. J., 2002, In: J LIPID RES. 43, 12, p. 1997-2006 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  6. No association between a genetic variant of the p22(phox) component of NAD(P)H oxidase and the incidence and progression of IgA nephropathy.

    Wolf, G., Panzer, U., Harendza, S., Wenzel, U. & Stahl, R. A. K., 2002, In: NEPHROL DIAL TRANSPL. 17, 8, p. 1509-1512 8.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  7. 2001
  8. Interaction with podocin facilitates nephrin signaling

    Huber, T. B., Kottgen, M., Schilling, B., Walz, G. & Benzing, T., 09.11.2001, In: J BIOL CHEM. 276, 45, p. 41543-6 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  9. Reassembly of the tight junction after oxidative stress depends on tyrosine kinase activity

    Meyer, T. N., Meyer-Schwesinger, C., Ye, J., Denker, B. M. & Nigam, S. K., 22.06.2001, In: J BIOL CHEM. 276, 25, p. 22048-55 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  10. Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium

    Meyer-Schwesinger, C., Yee, C., Rohan, R. M., Joussen, A. M., Fernandez, A., Meyer, T. N., Poulaki, V., Ma, J. J., Redmond, T. M., Liu, S., Adamis, A. P. & D'Amato, R. J., 01.03.2001, In: AM J PATHOL. 158, 3, p. 1161-72 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  11. Angiogenic potential of prostate carcinoma cells overexpressing bcl-2

    Fernandez, A., Udagawa, T., Meyer-Schwesinger, C., Beecken, W., Achilles-Gerte, E., McDonnell, T. & D'Amato, R., 07.02.2001, In: JNCI-J NATL CANCER I. 93, 3, p. 208-13 6 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  12. Angiotensin-converting enzyme inhibitors and progression of renal disease: evidence from clinical studies.

    Wenzel, U., 2001, In: CONTRIB NEPHROL. 135, p. 200-211

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  13. Angiotensin II induces p27(Kip1) expression in renal tubules in vivo: role of reactive oxygen species.

    Wolf, G., Wenzel, U., Hannken, T. & Stahl, R. A., 2001, In: J MOL MED. 79, 7, p. 382-389 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  14. A polymorphism, L162V, in the peroxisome proliferator-activated receptor alpha (PPARalpha) gene is associated with lower body mass index in patients with non-insulin-dependent diabetes mellitus.

    Evans, D., Aberle, J., Wendt, D., Wolf, A., Beisiegel, U. & Mann, W. A., 2001, In: J MOL MED. 79, 4, p. 198-204 4.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  15. Association between polymorphisms in candidate genes and morbid obesity.

    Evans, D., Wolf, A. M., Nellessen, U., Ahle, S., Kortner, B., Kuhlmann, H. W. & Beisiegel, U., 2001, In: INT J OBESITY. 25, 1, p. 19-21 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  16. Association between the P12A and c1431t polymorphisms in the peroxisome proliferator activated receptor gamma (PPAR gamma) gene and type 2 diabetes.

    Evans, D., de Heer, J., Hagemann, C., Wendt, D., Wolf, A., Beisiegel, U. & Mann, W. A., 2001, In: EXP CLIN ENDOCR DIAB. 109, 3, p. 151-154 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  17. Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice.

    Merkel, M., Velez-Carrasco, W., Hudgins, L. C. & Breslow, J. L., 2001, In: P NATL ACAD SCI USA. 98, 23, p. 13294-13299 23.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  18. Heparin-binding defective lipoprotein lipase is unstable and causes abnormalities in lipid delivery to tissues.

    Lutz, E. P., Merkel, M., Kako, Y., Melford, K., Radner, H., Breslow, J. L., Bensadoun, A. & Goldberg, I. J., 2001, In: J CLIN INVEST. 107, 9, p. 1183-1192 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  19. [Hypertensive disorders in pregnancy]

    Wolf, G., Wenzel, U., Stahl, R. A. & Hüneke, B., 2001, In: MED KLIN-INTENSIVMED. 96, 2, p. 78-86 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  20. Lipoprotein lipase: physiology, biochemistry, and molecular biology.

    Goldberg, I. J. & Merkel, M., 2001, In: FRONT BIOSCI-LANDMRK. 6, p. 388-405

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  21. [The treatment of arterial hypertension. An inquiry among doctors in general practice]

    Wenzel, U., Röben, T., Schwietzer, G. & Stahl, R. A., 2001, In: DEUT MED WOCHENSCHR. 126, 51-52, p. 1454-1459 51-52.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  22. 2000
  23. Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: studies in C57BL/6 apolipoprotein E knockout mice.

    Sehayek, E., Shefer, S., Nguyen, L. B., Ono, J. G., Merkel, M. & Breslow, J. L., 2000, In: P NATL ACAD SCI USA. 97, 7, p. 3433-3437 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  24. Frequency of and interaction between polymorphisms in the beta3-adrenergic receptor and in uncoupling proteins 1 and 2 and obesity in Germans.

    Evans, D., Minouchehr, S., Hagemann, G., Mann, W. A., Wendt, D., Wolf, A. & Beisiegel, U., 2000, In: INT J OBESITY. 24, 10, p. 1239-1245 10.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  25. Renal expression of aminopeptidase A in rats with two-kidney, one-clip hypertension.

    Wolf, G., Wenzel, U., Assmann, K. J. & Stahl, R. A., 2000, In: NEPHROL DIAL TRANSPL. 15, 12, p. 1935-1942 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  26. Renovascular hypertension does not influence repair of glomerular lesions induced by anti-thymocyte glomerulonephritis.

    Wenzel, U., Wolf, G., Thaiss, F., Helmchen, U. & Stahl, R. A., 2000, In: KIDNEY INT. 58, 3, p. 1135-1147 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  27. Variation in the gene for human peroxisome proliferator activated receptor gamma (PPARgamma) does not play a major role in the development of morbid obesity.

    Evans, D., Mann, W. A., de Heer, J., Michel, U., Wendt, D., Kortner, B., Wolf, A. & Beisiegel, U., 2000, In: INT J OBESITY. 24, 5, p. 647-651 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  28. 1999
  29. [A 73-year-old patient with hypertensive crisis. Was the use of calcium antagonist nifedipine justified?]

    Wenzel, U., Pfalzer, B., Meinertz, T. & Stahl, R. A., 1999, In: INTERNIST. 40, 2, p. 205-209 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  30. Angiotensin converting-enzyme inhibitor treatment reduces glomerular p16INK4 and p27Kip1 expression in diabetic BBdp rats.

    Wolf, G., Wenzel, U., Ziyadeh, F. N. & Stahl, R. A., 1999, In: DIABETOLOGIA. 42, 12, p. 1425-1432 12.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  31. Chemokines, renal disease, and HIV infection.

    Wenzel, U. & Stahl, R. A., 1999, In: NEPHRON. 81, 1, p. 5-16 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  32. Cyclooxygenase metabolites mediate glomerular monocyte chemoattractant protein-1 formation and monocyte recruitment in experimental glomerulonephritis.

    Schneider, A., Harendza, S., Zahner, G., Jocks, T., Wenzel, U., Wolf, G., Thaiss, F., Helmchen, U. & Stahl, R. A., 1999, In: KIDNEY INT. 55, 2, p. 430-441 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  33. Effect of renovascular hypertension on experimental glomerulonephritis in rats.

    Wenzel, U., Thaiss, F., Panzer, U., Schneider, A., Schwietzer, G., Helmchen, U. & Stahl, R. A., 1999, In: J LAB CLIN MED. 134, 3, p. 292-303 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  34. Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E.

    Marra, F., DeFranco, R., Grappone, C., Parola, M., Milani, S., Leonarduzzi, G., Pastacaldi, S., Wenzel, U., Pinzani, M., Dianzani, M. U., Laffi, G. & Gentilini, P., 1999, In: J INVEST MED. 47, 1, p. 66-75 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  35. High-level baculoviral expression of lysosomal acid lipase.

    Tilkorn, A. C., Merkel, M., Greten, H. & Meis, D., 1999, In: Methods Mol Biol. 109, p. 177-185

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  36. Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C.

    Heitzer, T., Wenzel, U., Hink, U., Krollner, D., Skatchkov, M., Stahl, R. A., MacHarzina, R., Bräsen, J. H., Meinertz, T. & Münzel, T., 1999, In: KIDNEY INT. 55, 1, p. 252-260 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  37. Lysosomal acid lipase. Assay and purification.

    Merkel, M., Tilkorn, A. C., Greten, H. & Ameis, D., 1999, In: Methods Mol Biol. 109, p. 95-107

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  38. Metabolic and genetic determinants of HDL metabolism and hepatic lipase activity in normolipidemic females.

    De Oliveira E Silva, E. R., Kong, M., Han, Z., Starr, C., Kass, E. M., Juo, S. H., Foster, D., Dansky, H. M., Merkel, M., Cundey, K., Brinton, E. A., Breslow, J. L. & Smith, J. D., 1999, In: J LIPID RES. 40, 7, p. 1211-1221 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  39. Monocyte chemoattractant protein-1 mediates collagen deposition in experimental glomerulonephritis by transforming growth factor-beta.

    Schneider, A., Panzer, U., Zahner, G., Wenzel, U., Wolf, G., Thaiss, F., Helmchen, U. & Stahl, R. A., 1999, In: KIDNEY INT. 56, 1, p. 135-144 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  40. 1998
  41. Catecholamines modulate podocyte function

    Huber, T. B., Gloy, J., Henger, A., Schollmeyer, P., Greger, R., Mundel, P. & Pavenstädt, H., 03.1998, In: J AM SOC NEPHROL. 9, 3, p. 335-45 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  42. A complex element regulates IFN-gamma-stimulated monocyte chemoattractant protein-1 gene transcription.

    Valente, A. J., Xie, J. F., Abramova, M. A., Wenzel, U., Abboud, H. E. & Graves, D. T., 1998, In: J IMMUNOL. 161, 7, p. 3719-3728 7.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  43. Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo.

    Merkel, M., Kako, Y., Radner, H., Cho, I. S., Ramasamy, R., Brunzell, J. D., Goldberg, I. J. & Breslow, J. L., 1998, In: P NATL ACAD SCI USA. 95, 23, p. 13841-13846 23.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  44. Compound heterozygosity for a new (S259G) and a previously described (G188E) mutation in lipoprotein lipase (LpL) as a cause of chylomicronemia. Mutations in brief no. 183. Online.

    Evans, D., Wendt, D., Ahle, S., Guerra, A. & Beisiegel, U., 1998, In: HUM MUTAT. 12, 3, p. 217 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  45. Expression of type III hyperlipoproteinemia in patients homozygous for apolipoprotein E-2 is modulated by lipoprotein lipase and postprandial hyperinsulinemia.

    Brümmer, D., Evans, D., Berg, D., Greten, H., Beisiegel, U. & Mann, W. A., 1998, In: J MOL MED. 76, 5, p. 355-364 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  46. L-arginine suppresses lipopolysaccharide-induced expression of RANTES in glomeruli.

    Haberstroh, U., Stilo, K., Pocock, J., Wolf, G., Helmchen, U., Wenzel, U., Zahner, G., Stahl, R. A. & Thaiss, F., 1998, In: J AM SOC NEPHROL. 9, 2, p. 203-210 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  47. Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia.

    Merkel, M., Weinstock, P. H., Chajek-Shaul, T., Radner, H., Yin, B., Breslow, J. L. & Goldberg, I. J., 1998, In: J CLIN INVEST. 102, 5, p. 893-901 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  48. Regulation of glomerular TGF-beta expression in the contralateral kidney of two-kidney, one-clip hypertensive rats.

    Wolf, G., Schneider, A., Wenzel, U., Helmchen, U. & Stahl, R. A., 1998, In: J AM SOC NEPHROL. 9, 5, p. 763-772 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  49. 1997
  50. Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor.

    Wolf, G., Ziyadeh, F. N., Thaiss, F., Tomaszewski, J., Caron, R. J., Wenzel, U., Zahner, G., Helmchen, U. & Stahl, R. A., 1997, In: J CLIN INVEST. 100, 5, p. 1047-1058 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  51. Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice.

    Weinstock, P. H., Bisgaier, C. L., Hayek, T., Aalto-Setala, K., Sehayek, E., Wu, L., Sheiffele, P., Merkel, M., Essenburg, A. D. & Breslow, J. L., 1997, In: J LIPID RES. 38, 9, p. 1782-1794 9.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  52. Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis.

    Wenzel, U., Schneider, A., Valente, A. J., Abboud, H. E., Thaiss, F., Helmchen, U. M. & Stahl, R. A., 1997, In: KIDNEY INT. 51, 3, p. 770-776 3.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  53. 1996
  54. [A new score for comparing outcome of surgical management of Achilles tendon ruptures]

    Merkel, M., Neumann, H. W. & Merk, H., 1996, In: CHIRURG. 67, 11, p. 1141-1146 11.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  55. Angiotensin-converting enzyme inhibition in experimental in-situ immune complex glomerulonephritis: influence on renal function, proteinuria, and morphology.

    Thaiss, F., Haas, C., Helmchen, U., Wenzel, U. & Stahl, R. A., 1996, In: NEPHROL DIAL TRANSPL. 11, 1, p. 40-46 1.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  56. Role of chemokines in glomerular diseases.

    Banas, B., Wenzel, U., Stahl, R. A. & Schlöndorff, D., 1996, In: KIDNEY BLOOD PRESS R. 19, 5, p. 270-280 5.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

  57. 1995
  58. A 5' splice-region mutation and a dinucleotide deletion in the lysosomal acid lipase gene in two patients with cholesteryl ester storage disease.

    Ameis, D., Brockmann, G., Knoblich, R., Merkel, M., Ostlund, R. E., Yang, J. W., Coates, P. M., Cortner, J. A., Feinman, S. V. & Greten, H., 1995, In: J LIPID RES. 36, 2, p. 241-250 2.

    Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review