III. Department of Medicine
Publications
- 2002
Eluate derived by extracorporal antibody-based immunoadsorption elevates the cytosolic Ca2+ concentration in podocytes via B2 kinin receptors
Fischer, K-G., Huber, T. B., Henger, A., Fink, E., Schwertfeger, E., Rump, L. C. & Pavenstädt, H., 2002, In: KIDNEY BLOOD PRESS R. 25, 6, p. 384-93 10 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Endothelial-derived lipoprotein lipase is bound to postprandial triglyceride-rich lipoproteins and mediates their hepatic clearance in vivo.
Heeren, J., Niemeier, A., Merkel, M. & Beisiegel, U., 2002, In: J MOL MED. 80, 9, p. 576-584 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake.
Merkel, M., Heeren, J., Dudeck, W., Rinninger, F., Radner, H., Breslow, J. L., Goldberg, I. J., Zechner, R. & Greten, H., 2002, In: J BIOL CHEM. 277, 9, p. 7405-7411 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lipoprotein lipase: genetics, lipid uptake, and regulation.
Merkel, M., Eckel, R. H. & Goldberg, I. J., 2002, In: J LIPID RES. 43, 12, p. 1997-2006 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
No association between a genetic variant of the p22(phox) component of NAD(P)H oxidase and the incidence and progression of IgA nephropathy.
Wolf, G., Panzer, U., Harendza, S., Wenzel, U. & Stahl, R. A. K., 2002, In: NEPHROL DIAL TRANSPL. 17, 8, p. 1509-1512 8.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2001
Interaction with podocin facilitates nephrin signaling
Huber, T. B., Kottgen, M., Schilling, B., Walz, G. & Benzing, T., 09.11.2001, In: J BIOL CHEM. 276, 45, p. 41543-6 4 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Reassembly of the tight junction after oxidative stress depends on tyrosine kinase activity
Meyer, T. N., Meyer-Schwesinger, C., Ye, J., Denker, B. M. & Nigam, S. K., 22.06.2001, In: J BIOL CHEM. 276, 25, p. 22048-55 8 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium
Meyer-Schwesinger, C., Yee, C., Rohan, R. M., Joussen, A. M., Fernandez, A., Meyer, T. N., Poulaki, V., Ma, J. J., Redmond, T. M., Liu, S., Adamis, A. P. & D'Amato, R. J., 01.03.2001, In: AM J PATHOL. 158, 3, p. 1161-72 12 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiogenic potential of prostate carcinoma cells overexpressing bcl-2
Fernandez, A., Udagawa, T., Meyer-Schwesinger, C., Beecken, W., Achilles-Gerte, E., McDonnell, T. & D'Amato, R., 07.02.2001, In: JNCI-J NATL CANCER I. 93, 3, p. 208-13 6 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin-converting enzyme inhibitors and progression of renal disease: evidence from clinical studies.
Wenzel, U., 2001, In: CONTRIB NEPHROL. 135, p. 200-211Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin II induces p27(Kip1) expression in renal tubules in vivo: role of reactive oxygen species.
Wolf, G., Wenzel, U., Hannken, T. & Stahl, R. A., 2001, In: J MOL MED. 79, 7, p. 382-389 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A polymorphism, L162V, in the peroxisome proliferator-activated receptor alpha (PPARalpha) gene is associated with lower body mass index in patients with non-insulin-dependent diabetes mellitus.
Evans, D., Aberle, J., Wendt, D., Wolf, A., Beisiegel, U. & Mann, W. A., 2001, In: J MOL MED. 79, 4, p. 198-204 4.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Association between polymorphisms in candidate genes and morbid obesity.
Evans, D., Wolf, A. M., Nellessen, U., Ahle, S., Kortner, B., Kuhlmann, H. W. & Beisiegel, U., 2001, In: INT J OBESITY. 25, 1, p. 19-21 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Association between the P12A and c1431t polymorphisms in the peroxisome proliferator activated receptor gamma (PPAR gamma) gene and type 2 diabetes.
Evans, D., de Heer, J., Hagemann, C., Wendt, D., Wolf, A., Beisiegel, U. & Mann, W. A., 2001, In: EXP CLIN ENDOCR DIAB. 109, 3, p. 151-154 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice.
Merkel, M., Velez-Carrasco, W., Hudgins, L. C. & Breslow, J. L., 2001, In: P NATL ACAD SCI USA. 98, 23, p. 13294-13299 23.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Heparin-binding defective lipoprotein lipase is unstable and causes abnormalities in lipid delivery to tissues.
Lutz, E. P., Merkel, M., Kako, Y., Melford, K., Radner, H., Breslow, J. L., Bensadoun, A. & Goldberg, I. J., 2001, In: J CLIN INVEST. 107, 9, p. 1183-1192 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[Hypertensive disorders in pregnancy]
Wolf, G., Wenzel, U., Stahl, R. A. & Hüneke, B., 2001, In: MED KLIN-INTENSIVMED. 96, 2, p. 78-86 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lipoprotein lipase: physiology, biochemistry, and molecular biology.
Goldberg, I. J. & Merkel, M., 2001, In: FRONT BIOSCI-LANDMRK. 6, p. 388-405Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
[The treatment of arterial hypertension. An inquiry among doctors in general practice]
Wenzel, U., Röben, T., Schwietzer, G. & Stahl, R. A., 2001, In: DEUT MED WOCHENSCHR. 126, 51-52, p. 1454-1459 51-52.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 2000
Apolipoprotein E regulates dietary cholesterol absorption and biliary cholesterol excretion: studies in C57BL/6 apolipoprotein E knockout mice.
Sehayek, E., Shefer, S., Nguyen, L. B., Ono, J. G., Merkel, M. & Breslow, J. L., 2000, In: P NATL ACAD SCI USA. 97, 7, p. 3433-3437 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Frequency of and interaction between polymorphisms in the beta3-adrenergic receptor and in uncoupling proteins 1 and 2 and obesity in Germans.
Evans, D., Minouchehr, S., Hagemann, G., Mann, W. A., Wendt, D., Wolf, A. & Beisiegel, U., 2000, In: INT J OBESITY. 24, 10, p. 1239-1245 10.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Renal expression of aminopeptidase A in rats with two-kidney, one-clip hypertension.
Wolf, G., Wenzel, U., Assmann, K. J. & Stahl, R. A., 2000, In: NEPHROL DIAL TRANSPL. 15, 12, p. 1935-1942 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Renovascular hypertension does not influence repair of glomerular lesions induced by anti-thymocyte glomerulonephritis.
Wenzel, U., Wolf, G., Thaiss, F., Helmchen, U. & Stahl, R. A., 2000, In: KIDNEY INT. 58, 3, p. 1135-1147 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Variation in the gene for human peroxisome proliferator activated receptor gamma (PPARgamma) does not play a major role in the development of morbid obesity.
Evans, D., Mann, W. A., de Heer, J., Michel, U., Wendt, D., Kortner, B., Wolf, A. & Beisiegel, U., 2000, In: INT J OBESITY. 24, 5, p. 647-651 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1999
[A 73-year-old patient with hypertensive crisis. Was the use of calcium antagonist nifedipine justified?]
Wenzel, U., Pfalzer, B., Meinertz, T. & Stahl, R. A., 1999, In: INTERNIST. 40, 2, p. 205-209 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin converting-enzyme inhibitor treatment reduces glomerular p16INK4 and p27Kip1 expression in diabetic BBdp rats.
Wolf, G., Wenzel, U., Ziyadeh, F. N. & Stahl, R. A., 1999, In: DIABETOLOGIA. 42, 12, p. 1425-1432 12.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Chemokines, renal disease, and HIV infection.
Wenzel, U. & Stahl, R. A., 1999, In: NEPHRON. 81, 1, p. 5-16 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Cyclooxygenase metabolites mediate glomerular monocyte chemoattractant protein-1 formation and monocyte recruitment in experimental glomerulonephritis.
Schneider, A., Harendza, S., Zahner, G., Jocks, T., Wenzel, U., Wolf, G., Thaiss, F., Helmchen, U. & Stahl, R. A., 1999, In: KIDNEY INT. 55, 2, p. 430-441 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Effect of renovascular hypertension on experimental glomerulonephritis in rats.
Wenzel, U., Thaiss, F., Panzer, U., Schneider, A., Schwietzer, G., Helmchen, U. & Stahl, R. A., 1999, In: J LAB CLIN MED. 134, 3, p. 292-303 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of monocyte chemotactic protein-1 precedes monocyte recruitment in a rat model of acute liver injury, and is modulated by vitamin E.
Marra, F., DeFranco, R., Grappone, C., Parola, M., Milani, S., Leonarduzzi, G., Pastacaldi, S., Wenzel, U., Pinzani, M., Dianzani, M. U., Laffi, G. & Gentilini, P., 1999, In: J INVEST MED. 47, 1, p. 66-75 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
High-level baculoviral expression of lysosomal acid lipase.
Tilkorn, A. C., Merkel, M., Greten, H. & Meis, D., 1999, In: Methods Mol Biol. 109, p. 177-185Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C.
Heitzer, T., Wenzel, U., Hink, U., Krollner, D., Skatchkov, M., Stahl, R. A., MacHarzina, R., Bräsen, J. H., Meinertz, T. & Münzel, T., 1999, In: KIDNEY INT. 55, 1, p. 252-260 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lysosomal acid lipase. Assay and purification.
Merkel, M., Tilkorn, A. C., Greten, H. & Ameis, D., 1999, In: Methods Mol Biol. 109, p. 95-107Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Metabolic and genetic determinants of HDL metabolism and hepatic lipase activity in normolipidemic females.
De Oliveira E Silva, E. R., Kong, M., Han, Z., Starr, C., Kass, E. M., Juo, S. H., Foster, D., Dansky, H. M., Merkel, M., Cundey, K., Brinton, E. A., Breslow, J. L. & Smith, J. D., 1999, In: J LIPID RES. 40, 7, p. 1211-1221 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monocyte chemoattractant protein-1 mediates collagen deposition in experimental glomerulonephritis by transforming growth factor-beta.
Schneider, A., Panzer, U., Zahner, G., Wenzel, U., Wolf, G., Thaiss, F., Helmchen, U. & Stahl, R. A., 1999, In: KIDNEY INT. 56, 1, p. 135-144 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1998
Catecholamines modulate podocyte function
Huber, T. B., Gloy, J., Henger, A., Schollmeyer, P., Greger, R., Mundel, P. & Pavenstädt, H., 03.1998, In: J AM SOC NEPHROL. 9, 3, p. 335-45 11 p.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
A complex element regulates IFN-gamma-stimulated monocyte chemoattractant protein-1 gene transcription.
Valente, A. J., Xie, J. F., Abramova, M. A., Wenzel, U., Abboud, H. E. & Graves, D. T., 1998, In: J IMMUNOL. 161, 7, p. 3719-3728 7.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo.
Merkel, M., Kako, Y., Radner, H., Cho, I. S., Ramasamy, R., Brunzell, J. D., Goldberg, I. J. & Breslow, J. L., 1998, In: P NATL ACAD SCI USA. 95, 23, p. 13841-13846 23.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Compound heterozygosity for a new (S259G) and a previously described (G188E) mutation in lipoprotein lipase (LpL) as a cause of chylomicronemia. Mutations in brief no. 183. Online.
Evans, D., Wendt, D., Ahle, S., Guerra, A. & Beisiegel, U., 1998, In: HUM MUTAT. 12, 3, p. 217 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Expression of type III hyperlipoproteinemia in patients homozygous for apolipoprotein E-2 is modulated by lipoprotein lipase and postprandial hyperinsulinemia.
Brümmer, D., Evans, D., Berg, D., Greten, H., Beisiegel, U. & Mann, W. A., 1998, In: J MOL MED. 76, 5, p. 355-364 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
L-arginine suppresses lipopolysaccharide-induced expression of RANTES in glomeruli.
Haberstroh, U., Stilo, K., Pocock, J., Wolf, G., Helmchen, U., Wenzel, U., Zahner, G., Stahl, R. A. & Thaiss, F., 1998, In: J AM SOC NEPHROL. 9, 2, p. 203-210 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia.
Merkel, M., Weinstock, P. H., Chajek-Shaul, T., Radner, H., Yin, B., Breslow, J. L. & Goldberg, I. J., 1998, In: J CLIN INVEST. 102, 5, p. 893-901 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Regulation of glomerular TGF-beta expression in the contralateral kidney of two-kidney, one-clip hypertensive rats.
Wolf, G., Schneider, A., Wenzel, U., Helmchen, U. & Stahl, R. A., 1998, In: J AM SOC NEPHROL. 9, 5, p. 763-772 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1997
Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor.
Wolf, G., Ziyadeh, F. N., Thaiss, F., Tomaszewski, J., Caron, R. J., Wenzel, U., Zahner, G., Helmchen, U. & Stahl, R. A., 1997, In: J CLIN INVEST. 100, 5, p. 1047-1058 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice.
Weinstock, P. H., Bisgaier, C. L., Hayek, T., Aalto-Setala, K., Sehayek, E., Wu, L., Sheiffele, P., Merkel, M., Essenburg, A. D. & Breslow, J. L., 1997, In: J LIPID RES. 38, 9, p. 1782-1794 9.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis.
Wenzel, U., Schneider, A., Valente, A. J., Abboud, H. E., Thaiss, F., Helmchen, U. M. & Stahl, R. A., 1997, In: KIDNEY INT. 51, 3, p. 770-776 3.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1996
[A new score for comparing outcome of surgical management of Achilles tendon ruptures]
Merkel, M., Neumann, H. W. & Merk, H., 1996, In: CHIRURG. 67, 11, p. 1141-1146 11.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Angiotensin-converting enzyme inhibition in experimental in-situ immune complex glomerulonephritis: influence on renal function, proteinuria, and morphology.
Thaiss, F., Haas, C., Helmchen, U., Wenzel, U. & Stahl, R. A., 1996, In: NEPHROL DIAL TRANSPL. 11, 1, p. 40-46 1.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
Role of chemokines in glomerular diseases.
Banas, B., Wenzel, U., Stahl, R. A. & Schlöndorff, D., 1996, In: KIDNEY BLOOD PRESS R. 19, 5, p. 270-280 5.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
- 1995
A 5' splice-region mutation and a dinucleotide deletion in the lysosomal acid lipase gene in two patients with cholesteryl ester storage disease.
Ameis, D., Brockmann, G., Knoblich, R., Merkel, M., Ostlund, R. E., Yang, J. W., Coates, P. M., Cortner, J. A., Feinman, S. V. & Greten, H., 1995, In: J LIPID RES. 36, 2, p. 241-250 2.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review