Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T cell-dependent liver injury in mice.

  • F Gantner
  • M Leist
  • S Jilg
  • P G Germann
  • M A Freudenberg
  • Gisa Tiegs

Abstract

The injection of mice with anti-CD3 monoclonal antibody causes activation of T lymphocytes and leads to a lethal shock syndrome. The aim of this study was to investigate T cell-dependent, cytokine-mediated target cell death that leads to organ injury.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer1
ISSN0016-5085
StatusVeröffentlicht - 1995
pubmed 7797015