The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings.
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The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings. / Puchner, Maximilian J A; Köppen, Johannes; Zapf, Svenja; Knabbe, Cornelius; Westphal, Manfred.
in: ANTICANCER RES, Jahrgang 22, Nr. 1, 1, 2002, S. 45-51.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings.
AU - Puchner, Maximilian J A
AU - Köppen, Johannes
AU - Zapf, Svenja
AU - Knabbe, Cornelius
AU - Westphal, Manfred
PY - 2002
Y1 - 2002
N2 - Only a minority of patients with malignant gliomas respond to continuous high-dose tamoxifen (TAM) treatment. Therefore a method to predict the efficiency of TAM-treatment would be desirable. Analogous to previous studies in breast cancer patients, we investigated whether the dynamics of TGF-beta2 plasma levels allow the prediction of response to TAM-treatment in glioblastoma patients as well.
AB - Only a minority of patients with malignant gliomas respond to continuous high-dose tamoxifen (TAM) treatment. Therefore a method to predict the efficiency of TAM-treatment would be desirable. Analogous to previous studies in breast cancer patients, we investigated whether the dynamics of TGF-beta2 plasma levels allow the prediction of response to TAM-treatment in glioblastoma patients as well.
M3 - SCORING: Zeitschriftenaufsatz
VL - 22
SP - 45
EP - 51
JO - ANTICANCER RES
JF - ANTICANCER RES
SN - 0250-7005
IS - 1
M1 - 1
ER -