The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings.

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The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings. / Puchner, Maximilian J A; Köppen, Johannes; Zapf, Svenja; Knabbe, Cornelius; Westphal, Manfred.

In: ANTICANCER RES, Vol. 22, No. 1, 1, 2002, p. 45-51.

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@article{a6453c8daaa046db83dfeec4cc77e5a8,
title = "The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings.",
abstract = "Only a minority of patients with malignant gliomas respond to continuous high-dose tamoxifen (TAM) treatment. Therefore a method to predict the efficiency of TAM-treatment would be desirable. Analogous to previous studies in breast cancer patients, we investigated whether the dynamics of TGF-beta2 plasma levels allow the prediction of response to TAM-treatment in glioblastoma patients as well.",
author = "Puchner, {Maximilian J A} and Johannes K{\"o}ppen and Svenja Zapf and Cornelius Knabbe and Manfred Westphal",
year = "2002",
language = "Deutsch",
volume = "22",
pages = "45--51",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "1",

}

RIS

TY - JOUR

T1 - The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings.

AU - Puchner, Maximilian J A

AU - Köppen, Johannes

AU - Zapf, Svenja

AU - Knabbe, Cornelius

AU - Westphal, Manfred

PY - 2002

Y1 - 2002

N2 - Only a minority of patients with malignant gliomas respond to continuous high-dose tamoxifen (TAM) treatment. Therefore a method to predict the efficiency of TAM-treatment would be desirable. Analogous to previous studies in breast cancer patients, we investigated whether the dynamics of TGF-beta2 plasma levels allow the prediction of response to TAM-treatment in glioblastoma patients as well.

AB - Only a minority of patients with malignant gliomas respond to continuous high-dose tamoxifen (TAM) treatment. Therefore a method to predict the efficiency of TAM-treatment would be desirable. Analogous to previous studies in breast cancer patients, we investigated whether the dynamics of TGF-beta2 plasma levels allow the prediction of response to TAM-treatment in glioblastoma patients as well.

M3 - SCORING: Zeitschriftenaufsatz

VL - 22

SP - 45

EP - 51

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 1

M1 - 1

ER -