The influence of tamoxifen on the secretion of transforming growth factor-beta2 (TGF-beta2) in glioblastomas: in vitro and in vivo findings.

  • Maximilian J A Puchner
  • Johannes Köppen
  • Svenja Zapf
  • Cornelius Knabbe
  • Manfred Westphal

Beteiligte Einrichtungen

Abstract

Only a minority of patients with malignant gliomas respond to continuous high-dose tamoxifen (TAM) treatment. Therefore a method to predict the efficiency of TAM-treatment would be desirable. Analogous to previous studies in breast cancer patients, we investigated whether the dynamics of TGF-beta2 plasma levels allow the prediction of response to TAM-treatment in glioblastoma patients as well.

Bibliografische Daten

OriginalspracheDeutsch
Aufsatznummer1
ISSN0250-7005
StatusVeröffentlicht - 2002
pubmed 12017331