Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases?
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Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases? / Erdmann, Robert; Ozden, Cansu; Weidmann, Jens; Schultze, Alexander.
in: J PATHOL, Jahrgang 236, Nr. 4, 08.2015, S. 403-6.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases?
AU - Erdmann, Robert
AU - Ozden, Cansu
AU - Weidmann, Jens
AU - Schultze, Alexander
N1 - Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
PY - 2015/8
Y1 - 2015/8
N2 - Published recently in the Journal of Pathology, Lavoz et al. show that Gremlin promotes renal inflammation directly via VEGFR2. As Gremlin has been implicated in many other diseases, such as heart, lung and liver fibrosis, osteogenesis, angiogenesis and cancer, the new findings provide a rationale for novel concepts to investigate and potentially treat several pathologies.
AB - Published recently in the Journal of Pathology, Lavoz et al. show that Gremlin promotes renal inflammation directly via VEGFR2. As Gremlin has been implicated in many other diseases, such as heart, lung and liver fibrosis, osteogenesis, angiogenesis and cancer, the new findings provide a rationale for novel concepts to investigate and potentially treat several pathologies.
KW - Animals
KW - Female
KW - Humans
KW - Inflammation Mediators
KW - Intercellular Signaling Peptides and Proteins
KW - Kidney
KW - Male
KW - Nephritis
KW - Vascular Endothelial Growth Factor Receptor-2
U2 - 10.1002/path.4544
DO - 10.1002/path.4544
M3 - SCORING: Journal article
C2 - 25875212
VL - 236
SP - 403
EP - 406
JO - J PATHOL
JF - J PATHOL
SN - 0022-3417
IS - 4
ER -