Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases?

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Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases? / Erdmann, Robert; Ozden, Cansu; Weidmann, Jens; Schultze, Alexander.

In: J PATHOL, Vol. 236, No. 4, 08.2015, p. 403-6.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{db2b422e1d094176b026d4820d83973a,
title = "Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases?",
abstract = "Published recently in the Journal of Pathology, Lavoz et al. show that Gremlin promotes renal inflammation directly via VEGFR2. As Gremlin has been implicated in many other diseases, such as heart, lung and liver fibrosis, osteogenesis, angiogenesis and cancer, the new findings provide a rationale for novel concepts to investigate and potentially treat several pathologies.",
keywords = "Animals, Female, Humans, Inflammation Mediators, Intercellular Signaling Peptides and Proteins, Kidney, Male, Nephritis, Vascular Endothelial Growth Factor Receptor-2",
author = "Robert Erdmann and Cansu Ozden and Jens Weidmann and Alexander Schultze",
note = "Copyright {\textcopyright} 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.",
year = "2015",
month = aug,
doi = "10.1002/path.4544",
language = "English",
volume = "236",
pages = "403--6",
journal = "J PATHOL",
issn = "0022-3417",
publisher = "John Wiley and Sons Ltd",
number = "4",

}

RIS

TY - JOUR

T1 - Targeting the Gremlin-VEGFR2 axis - a promising strategy for multiple diseases?

AU - Erdmann, Robert

AU - Ozden, Cansu

AU - Weidmann, Jens

AU - Schultze, Alexander

N1 - Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

PY - 2015/8

Y1 - 2015/8

N2 - Published recently in the Journal of Pathology, Lavoz et al. show that Gremlin promotes renal inflammation directly via VEGFR2. As Gremlin has been implicated in many other diseases, such as heart, lung and liver fibrosis, osteogenesis, angiogenesis and cancer, the new findings provide a rationale for novel concepts to investigate and potentially treat several pathologies.

AB - Published recently in the Journal of Pathology, Lavoz et al. show that Gremlin promotes renal inflammation directly via VEGFR2. As Gremlin has been implicated in many other diseases, such as heart, lung and liver fibrosis, osteogenesis, angiogenesis and cancer, the new findings provide a rationale for novel concepts to investigate and potentially treat several pathologies.

KW - Animals

KW - Female

KW - Humans

KW - Inflammation Mediators

KW - Intercellular Signaling Peptides and Proteins

KW - Kidney

KW - Male

KW - Nephritis

KW - Vascular Endothelial Growth Factor Receptor-2

U2 - 10.1002/path.4544

DO - 10.1002/path.4544

M3 - SCORING: Journal article

C2 - 25875212

VL - 236

SP - 403

EP - 406

JO - J PATHOL

JF - J PATHOL

SN - 0022-3417

IS - 4

ER -