In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.
Beteiligte Einrichtungen
Abstract
The purpose of this study was to examine whether the epidermal growth factor receptor (EGFR) may be used as a general target to modulate DNA double strand break (DSB) repair in tumor cells.
Bibliografische Daten
| Originalsprache | Englisch |
|---|---|
| Aufsatznummer | 1 |
| ISSN | 0167-8140 |
| Status | Veröffentlicht - 2011 |
| pubmed | 21665306 |
|---|
