In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.
Related Research units
Abstract
The purpose of this study was to examine whether the epidermal growth factor receptor (EGFR) may be used as a general target to modulate DNA double strand break (DSB) repair in tumor cells.
Bibliographical data
| Original language | English |
|---|---|
| Article number | 1 |
| ISSN | 0167-8140 |
| Publication status | Published - 2011 |
| pubmed | 21665306 |
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