Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus
Standard
Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus. / Evers, Andrea W M; Colloca, Luana; Blease, Charlotte; Annoni, Marco; Atlas, Lauren Y; Benedetti, Fabrizio; Bingel, Ulrike; Büchel, Christian; Carvalho, Claudia; Colagiuri, Ben; Crum, Alia J; Enck, Paul; Gaab, Jens; Geers, Andrew L; Howick, Jeremy; Jensen, Karin B; Kirsch, Irving; Meissner, Karin; Napadow, Vitaly; Peerdeman, Kaya J; Raz, Amir; Rief, Winfried; Vase, Lene; Wager, Tor D; Wampold, Bruce E; Weimer, Katja; Wiech, Katja; Kaptchuk, Ted J; Klinger, Regine; Kelley, John M.
in: PSYCHOTHER PSYCHOSOM, Jahrgang 87, Nr. 4, 07.2018, S. 204-210.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Implications of Placebo and Nocebo Effects for Clinical Practice: Expert Consensus
AU - Evers, Andrea W M
AU - Colloca, Luana
AU - Blease, Charlotte
AU - Annoni, Marco
AU - Atlas, Lauren Y
AU - Benedetti, Fabrizio
AU - Bingel, Ulrike
AU - Büchel, Christian
AU - Carvalho, Claudia
AU - Colagiuri, Ben
AU - Crum, Alia J
AU - Enck, Paul
AU - Gaab, Jens
AU - Geers, Andrew L
AU - Howick, Jeremy
AU - Jensen, Karin B
AU - Kirsch, Irving
AU - Meissner, Karin
AU - Napadow, Vitaly
AU - Peerdeman, Kaya J
AU - Raz, Amir
AU - Rief, Winfried
AU - Vase, Lene
AU - Wager, Tor D
AU - Wampold, Bruce E
AU - Weimer, Katja
AU - Wiech, Katja
AU - Kaptchuk, Ted J
AU - Klinger, Regine
AU - Kelley, John M
N1 - © 2018 S. Karger AG, Basel.
PY - 2018/7
Y1 - 2018/7
N2 - BACKGROUND: Placebo and nocebo effects occur in clinical or laboratory medical contexts after administration of an inert treatment or as part of active treatments and are due to psychobiological mechanisms such as expectancies of the patient. Placebo and nocebo studies have evolved from predominantly methodological research into a far-reaching interdisciplinary field that is unravelling the neurobiological, behavioural and clinical underpinnings of these phenomena in a broad variety of medical conditions. As a consequence, there is an increasing demand from health professionals to develop expert recommendations about evidence-based and ethical use of placebo and nocebo effects for clinical practice.METHODS: A survey and interdisciplinary expert meeting by invitation was organized as part of the 1st Society for Interdisciplinary Placebo Studies (SIPS) conference in 2017. Twenty-nine internationally recognized placebo researchers participated.RESULTS: There was consensus that maximizing placebo effects and minimizing nocebo effects should lead to better treatment outcomes with fewer side effects. Experts particularly agreed on the importance of informing patients about placebo and nocebo effects and training health professionals in patient-clinician communication to maximize placebo and minimize nocebo effects.CONCLUSIONS: The current paper forms a first step towards developing evidence-based and ethical recommendations about the implications of placebo and nocebo research for medical practice, based on the current state of evidence and the consensus of experts. Future research might focus on how to implement these recommendations, including how to optimize conditions for educating patients about placebo and nocebo effects and providing training for the implementation in clinical practice.
AB - BACKGROUND: Placebo and nocebo effects occur in clinical or laboratory medical contexts after administration of an inert treatment or as part of active treatments and are due to psychobiological mechanisms such as expectancies of the patient. Placebo and nocebo studies have evolved from predominantly methodological research into a far-reaching interdisciplinary field that is unravelling the neurobiological, behavioural and clinical underpinnings of these phenomena in a broad variety of medical conditions. As a consequence, there is an increasing demand from health professionals to develop expert recommendations about evidence-based and ethical use of placebo and nocebo effects for clinical practice.METHODS: A survey and interdisciplinary expert meeting by invitation was organized as part of the 1st Society for Interdisciplinary Placebo Studies (SIPS) conference in 2017. Twenty-nine internationally recognized placebo researchers participated.RESULTS: There was consensus that maximizing placebo effects and minimizing nocebo effects should lead to better treatment outcomes with fewer side effects. Experts particularly agreed on the importance of informing patients about placebo and nocebo effects and training health professionals in patient-clinician communication to maximize placebo and minimize nocebo effects.CONCLUSIONS: The current paper forms a first step towards developing evidence-based and ethical recommendations about the implications of placebo and nocebo research for medical practice, based on the current state of evidence and the consensus of experts. Future research might focus on how to implement these recommendations, including how to optimize conditions for educating patients about placebo and nocebo effects and providing training for the implementation in clinical practice.
KW - Journal Article
U2 - 10.1159/000490354
DO - 10.1159/000490354
M3 - SCORING: Journal article
C2 - 29895014
VL - 87
SP - 204
EP - 210
JO - PSYCHOTHER PSYCHOSOM
JF - PSYCHOTHER PSYCHOSOM
SN - 0033-3190
IS - 4
ER -