Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion.

Sönke Cordeiro; Sebastian Seyler; Julia Stindl; Vladimir M Milenkovic; Olaf Strauss

doi:10.1167/iovs.09-4720

Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion.

Sönke Cordeiro
Sebastian Seyler
Julia Stindl
Vladimir M Milenkovic
Olaf Strauss

Beteiligte Einrichtungen

Klinik und Poliklinik für Augenheilkunde

Abstract

Choroidal neovascularization in age-related macular degeneration is caused, to a large extent, by increased secretion of vascular endothelial growth factor (VEGF)-A by the retinal pigment epithelium (RPE). The purpose of the study was to identify pathways that lead to increased VEGF secretion by the RPE.

Bibliografische Daten

Originalsprache	Deutsch
Aufsatznummer	11
ISSN	0146-0404
DOIs	https://doi.org/10.1167/iovs.09-4720
Status	Veröffentlicht - 2010

pubmed	20539001