Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion.

  • Sönke Cordeiro
  • Sebastian Seyler
  • Julia Stindl
  • Vladimir M Milenkovic
  • Olaf Strauss

Related Research units

Abstract

Choroidal neovascularization in age-related macular degeneration is caused, to a large extent, by increased secretion of vascular endothelial growth factor (VEGF)-A by the retinal pigment epithelium (RPE). The purpose of the study was to identify pathways that lead to increased VEGF secretion by the RPE.

Bibliographical data

Original languageGerman
Article number11
ISSN0146-0404
DOIs
Publication statusPublished - 2010
pubmed 20539001