Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion.
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Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion. / Cordeiro, Sönke; Seyler, Sebastian; Stindl, Julia; Milenkovic, Vladimir M; Strauss, Olaf.
in: INVEST OPHTH VIS SCI, Jahrgang 51, Nr. 11, 11, 2010, S. 6001-6008.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Heat-sensitive TRPV channels in retinal pigment epithelial cells: regulation of VEGF-A secretion.
AU - Cordeiro, Sönke
AU - Seyler, Sebastian
AU - Stindl, Julia
AU - Milenkovic, Vladimir M
AU - Strauss, Olaf
PY - 2010
Y1 - 2010
N2 - Choroidal neovascularization in age-related macular degeneration is caused, to a large extent, by increased secretion of vascular endothelial growth factor (VEGF)-A by the retinal pigment epithelium (RPE). The purpose of the study was to identify pathways that lead to increased VEGF secretion by the RPE.
AB - Choroidal neovascularization in age-related macular degeneration is caused, to a large extent, by increased secretion of vascular endothelial growth factor (VEGF)-A by the retinal pigment epithelium (RPE). The purpose of the study was to identify pathways that lead to increased VEGF secretion by the RPE.
KW - Humans
KW - inhibitors
KW - Calcium Signaling physiology
KW - Reverse Transcriptase Polymerase Chain Reaction
KW - Enzyme-Linked Immunosorbent Assay
KW - Calcium metabolism
KW - Patch-Clamp Techniques
KW - Membrane Potentials drug effects
KW - Cell Line
KW - Hot Temperature
KW - Insulin-Like Growth Factor I pharmacology
KW - Lanthanum pharmacology
KW - Retinal Pigment Epithelium drug effects
KW - Ruthenium Red pharmacology
KW - TRPV Cation Channels antagonists
KW - Vascular Endothelial Growth Factor A metabolism
KW - Humans
KW - inhibitors
KW - Calcium Signaling physiology
KW - Reverse Transcriptase Polymerase Chain Reaction
KW - Enzyme-Linked Immunosorbent Assay
KW - Calcium metabolism
KW - Patch-Clamp Techniques
KW - Membrane Potentials drug effects
KW - Cell Line
KW - Hot Temperature
KW - Insulin-Like Growth Factor I pharmacology
KW - Lanthanum pharmacology
KW - Retinal Pigment Epithelium drug effects
KW - Ruthenium Red pharmacology
KW - TRPV Cation Channels antagonists
KW - Vascular Endothelial Growth Factor A metabolism
U2 - 10.1167/iovs.09-4720
DO - 10.1167/iovs.09-4720
M3 - SCORING: Zeitschriftenaufsatz
VL - 51
SP - 6001
EP - 6008
JO - INVEST OPHTH VIS SCI
JF - INVEST OPHTH VIS SCI
SN - 0146-0404
IS - 11
M1 - 11
ER -