Dicentric (19;21)(p13;p13), a novel chromosomal abnormality occurring in a case of Philadelphia chromosome-positive acute lymphoblastic leukemia.

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Dicentric (19;21)(p13;p13), a novel chromosomal abnormality occurring in a case of Philadelphia chromosome-positive acute lymphoblastic leukemia. / Schilling, Georgia; Dierlamm, Judith; Murga-Penas, Eva-Maria; Hinz, Kristina; Seeger, Doris; Hossfeld, Dieter Kurt.

in: CANCER GENET-NY, Jahrgang 152, Nr. 2, 2, 2004, S. 129-131.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{eadb3fb724774d29b5d3afd146fa043d,
title = "Dicentric (19;21)(p13;p13), a novel chromosomal abnormality occurring in a case of Philadelphia chromosome-positive acute lymphoblastic leukemia.",
abstract = "We report on a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia, who acquired a novel chromosomal abnormality, a dic(19;21)(p13;p13), during relapse of the disease. The cytogenetic result was confirmed by fluorescence in situ hybridization using alpha-satellite and library probes specific for chromosomes 19 and 21, respectively, as well as a chromosome 19q13.1-specific DNA probe. In our case, the dic(19;21) represents a secondary genetic change and was associated with disease progression and poor prognosis.",
author = "Georgia Schilling and Judith Dierlamm and Eva-Maria Murga-Penas and Kristina Hinz and Doris Seeger and Hossfeld, {Dieter Kurt}",
year = "2004",
language = "Deutsch",
volume = "152",
pages = "129--131",
journal = "CANCER GENET-NY",
issn = "2210-7762",
publisher = "Elsevier BV",
number = "2",

}

RIS

TY - JOUR

T1 - Dicentric (19;21)(p13;p13), a novel chromosomal abnormality occurring in a case of Philadelphia chromosome-positive acute lymphoblastic leukemia.

AU - Schilling, Georgia

AU - Dierlamm, Judith

AU - Murga-Penas, Eva-Maria

AU - Hinz, Kristina

AU - Seeger, Doris

AU - Hossfeld, Dieter Kurt

PY - 2004

Y1 - 2004

N2 - We report on a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia, who acquired a novel chromosomal abnormality, a dic(19;21)(p13;p13), during relapse of the disease. The cytogenetic result was confirmed by fluorescence in situ hybridization using alpha-satellite and library probes specific for chromosomes 19 and 21, respectively, as well as a chromosome 19q13.1-specific DNA probe. In our case, the dic(19;21) represents a secondary genetic change and was associated with disease progression and poor prognosis.

AB - We report on a patient with Philadelphia chromosome-positive acute lymphoblastic leukemia, who acquired a novel chromosomal abnormality, a dic(19;21)(p13;p13), during relapse of the disease. The cytogenetic result was confirmed by fluorescence in situ hybridization using alpha-satellite and library probes specific for chromosomes 19 and 21, respectively, as well as a chromosome 19q13.1-specific DNA probe. In our case, the dic(19;21) represents a secondary genetic change and was associated with disease progression and poor prognosis.

M3 - SCORING: Zeitschriftenaufsatz

VL - 152

SP - 129

EP - 131

JO - CANCER GENET-NY

JF - CANCER GENET-NY

SN - 2210-7762

IS - 2

M1 - 2

ER -