Chloride accumulation in endosomes and lysosomes: facts checked in mice

Blanche Schwappach

doi:10.15252/embj.2020104812

Chloride accumulation in endosomes and lysosomes: facts checked in mice

Standard

Chloride accumulation in endosomes and lysosomes: facts checked in mice. / Schwappach, Blanche.

in: EMBO J, Jahrgang 39, Nr. 9, 04.05.2020, S. e104812.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Schwappach, B 2020, 'Chloride accumulation in endosomes and lysosomes: facts checked in mice', EMBO J, Jg. 39, Nr. 9, S. e104812. https://doi.org/10.15252/embj.2020104812

APA

Schwappach, B. (2020). Chloride accumulation in endosomes and lysosomes: facts checked in mice. EMBO J, 39(9), e104812. https://doi.org/10.15252/embj.2020104812

Vancouver

Schwappach B. Chloride accumulation in endosomes and lysosomes: facts checked in mice. EMBO J. 2020 Mai 4;39(9):e104812. https://doi.org/10.15252/embj.2020104812

Bibtex

@article{cc692534ba134e5baef589d6cf0a5842,

title = "Chloride accumulation in endosomes and lysosomes: facts checked in mice",

abstract = "Loss of the ClC-3 chloride/proton exchanger found in intracellular compartments leads to marked neurodegeneration. New genetic work by Weinert et al (2020) now shows that selective impairment of ClC-3's ion exchange activity is sufficient to elicit this severe phenotype in vivo. ClC-3 cooperates with the closely related ClC-4 in protecting endolysosomal chloride balance and neuronal integrity.",

author = "Blanche Schwappach",

note = "{\textcopyright} 2020 The Author.",

year = "2020",

month = may,

day = "4",

doi = "10.15252/embj.2020104812",

language = "English",

volume = "39",

pages = "e104812",

journal = "EMBO J",

issn = "0261-4189",

publisher = "NATURE PUBLISHING GROUP",

number = "9",

}

RIS

TY - JOUR

T1 - Chloride accumulation in endosomes and lysosomes: facts checked in mice

AU - Schwappach, Blanche

PY - 2020/5/4

Y1 - 2020/5/4

N2 - Loss of the ClC-3 chloride/proton exchanger found in intracellular compartments leads to marked neurodegeneration. New genetic work by Weinert et al (2020) now shows that selective impairment of ClC-3's ion exchange activity is sufficient to elicit this severe phenotype in vivo. ClC-3 cooperates with the closely related ClC-4 in protecting endolysosomal chloride balance and neuronal integrity.

AB - Loss of the ClC-3 chloride/proton exchanger found in intracellular compartments leads to marked neurodegeneration. New genetic work by Weinert et al (2020) now shows that selective impairment of ClC-3's ion exchange activity is sufficient to elicit this severe phenotype in vivo. ClC-3 cooperates with the closely related ClC-4 in protecting endolysosomal chloride balance and neuronal integrity.

U2 - 10.15252/embj.2020104812

DO - 10.15252/embj.2020104812

M3 - SCORING: Journal article

C2 - 32270512

VL - 39

SP - e104812

JO - EMBO J

JF - EMBO J

SN - 0261-4189

IS - 9

ER -