Vaccination against tuberculosis

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Vaccination against tuberculosis : current status and future promise. / Kaufmann, Stefan H; Mittrücker, Hans-Willi.

In: SEMIN RESP CRIT CARE, Vol. 25, No. 3, 01.06.2004, p. 345-52.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{0733c30986784836a07d1a2e93d91ca1,
title = "Vaccination against tuberculosis: current status and future promise",
abstract = "Tuberculosis remains a major health threat. The currently available vaccine, bacille Calmette-Gu{\'e}rin (BCG), provides insufficient protection, and multi-drug-resistant strains are on the rise. A novel vaccine with higher efficacy is needed for satisfactory control of the disease. Currently, several novel vaccine candidates are being tested in preclinical models with promising outcome, but none with overwhelming success. The final decision as to whether an efficacious vaccine can be designed will have to await the outcome of a clinical trial comprising the most promising candidates identified by experimental animal studies.",
author = "Kaufmann, {Stefan H} and Hans-Willi Mittr{\"u}cker",
year = "2004",
month = jun,
day = "1",
doi = "10.1055/s-2004-829506",
language = "English",
volume = "25",
pages = "345--52",
journal = "SEMIN RESP CRIT CARE",
issn = "1069-3424",
publisher = "Thieme Medical Publishers",
number = "3",

}

RIS

TY - JOUR

T1 - Vaccination against tuberculosis

T2 - current status and future promise

AU - Kaufmann, Stefan H

AU - Mittrücker, Hans-Willi

PY - 2004/6/1

Y1 - 2004/6/1

N2 - Tuberculosis remains a major health threat. The currently available vaccine, bacille Calmette-Guérin (BCG), provides insufficient protection, and multi-drug-resistant strains are on the rise. A novel vaccine with higher efficacy is needed for satisfactory control of the disease. Currently, several novel vaccine candidates are being tested in preclinical models with promising outcome, but none with overwhelming success. The final decision as to whether an efficacious vaccine can be designed will have to await the outcome of a clinical trial comprising the most promising candidates identified by experimental animal studies.

AB - Tuberculosis remains a major health threat. The currently available vaccine, bacille Calmette-Guérin (BCG), provides insufficient protection, and multi-drug-resistant strains are on the rise. A novel vaccine with higher efficacy is needed for satisfactory control of the disease. Currently, several novel vaccine candidates are being tested in preclinical models with promising outcome, but none with overwhelming success. The final decision as to whether an efficacious vaccine can be designed will have to await the outcome of a clinical trial comprising the most promising candidates identified by experimental animal studies.

U2 - 10.1055/s-2004-829506

DO - 10.1055/s-2004-829506

M3 - SCORING: Journal article

C2 - 16088475

VL - 25

SP - 345

EP - 352

JO - SEMIN RESP CRIT CARE

JF - SEMIN RESP CRIT CARE

SN - 1069-3424

IS - 3

ER -