Vaccination against tuberculosis
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Vaccination against tuberculosis : current status and future promise. / Kaufmann, Stefan H; Mittrücker, Hans-Willi.
in: SEMIN RESP CRIT CARE, Jahrgang 25, Nr. 3, 01.06.2004, S. 345-52.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Vaccination against tuberculosis
T2 - current status and future promise
AU - Kaufmann, Stefan H
AU - Mittrücker, Hans-Willi
PY - 2004/6/1
Y1 - 2004/6/1
N2 - Tuberculosis remains a major health threat. The currently available vaccine, bacille Calmette-Guérin (BCG), provides insufficient protection, and multi-drug-resistant strains are on the rise. A novel vaccine with higher efficacy is needed for satisfactory control of the disease. Currently, several novel vaccine candidates are being tested in preclinical models with promising outcome, but none with overwhelming success. The final decision as to whether an efficacious vaccine can be designed will have to await the outcome of a clinical trial comprising the most promising candidates identified by experimental animal studies.
AB - Tuberculosis remains a major health threat. The currently available vaccine, bacille Calmette-Guérin (BCG), provides insufficient protection, and multi-drug-resistant strains are on the rise. A novel vaccine with higher efficacy is needed for satisfactory control of the disease. Currently, several novel vaccine candidates are being tested in preclinical models with promising outcome, but none with overwhelming success. The final decision as to whether an efficacious vaccine can be designed will have to await the outcome of a clinical trial comprising the most promising candidates identified by experimental animal studies.
U2 - 10.1055/s-2004-829506
DO - 10.1055/s-2004-829506
M3 - SCORING: Journal article
C2 - 16088475
VL - 25
SP - 345
EP - 352
JO - SEMIN RESP CRIT CARE
JF - SEMIN RESP CRIT CARE
SN - 1069-3424
IS - 3
ER -