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Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology.

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Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology. / Petry, K Ulrich; Schmidt, Dietmar; Scherbring, Sarah; Luyten, Alexander; Reinecke-Lüthge, Axel; Bergeron, Christine; Kommoss, Friedrich; Löning, Thomas; Ordi, Jaume; Regauer, Sigrid; Ridder, Ruediger.

In: GYNECOL ONCOL, Vol. 121, No. 3, 3, 2011, p. 505-509.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Petry, KU, Schmidt, D, Scherbring, S, Luyten, A, Reinecke-Lüthge, A, Bergeron, C, Kommoss, F, Löning, T, Ordi, J, Regauer, S & Ridder, R 2011, 'Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology.', GYNECOL ONCOL, vol. 121, no. 3, 3, pp. 505-509. <http://www.ncbi.nlm.nih.gov/pubmed/21420158?dopt=Citation>

APA

Petry, K. U., Schmidt, D., Scherbring, S., Luyten, A., Reinecke-Lüthge, A., Bergeron, C., Kommoss, F., Löning, T., Ordi, J., Regauer, S., & Ridder, R. (2011). Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology. GYNECOL ONCOL, 121(3), 505-509. [3]. http://www.ncbi.nlm.nih.gov/pubmed/21420158?dopt=Citation

Vancouver

Petry KU, Schmidt D, Scherbring S, Luyten A, Reinecke-Lüthge A, Bergeron C et al. Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology. GYNECOL ONCOL. 2011;121(3):505-509. 3.

Bibtex

@article{15120996d4cc4ab79e81ad83beb30343,
title = "Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology.",
abstract = "Testing for human papillomavirus (HPV) has been shown to increase the sensitivity and negative predictive value for detection of high-grade cervical intraepithelial neoplasia (CIN2+), either when used in conjunction with Pap cytology testing or alone. However, there is no satisfying clinical management algorithm for women testing Pap negative/HPV positive. We therefore evaluated the clinical utility of a novel dual biomarker-based approach (p16/Ki-67 Dual-stained cytology) for the identification of CIN2+ in women with Pap negative/HPV positive screening results, without the need to refer all women to immediate colposcopy.",
keywords = "Adult, Humans, Aged, Female, Middle Aged, Aged, 80 and over, Cohort Studies, Sensitivity and Specificity, Vaginal Smears, Neoplasm Proteins/*metabolism, Ki-67 Antigen/*metabolism, Staining and Labeling/methods, Cervical Intraepithelial Neoplasia/metabolism/*pathology/*virology, Papillomavirus Infections/metabolism/*pathology/virology, Uterine Cervical Neoplasms/metabolism/*pathology/*virology, Adult, Humans, Aged, Female, Middle Aged, Aged, 80 and over, Cohort Studies, Sensitivity and Specificity, Vaginal Smears, Neoplasm Proteins/*metabolism, Ki-67 Antigen/*metabolism, Staining and Labeling/methods, Cervical Intraepithelial Neoplasia/metabolism/*pathology/*virology, Papillomavirus Infections/metabolism/*pathology/virology, Uterine Cervical Neoplasms/metabolism/*pathology/*virology",
author = "Petry, {K Ulrich} and Dietmar Schmidt and Sarah Scherbring and Alexander Luyten and Axel Reinecke-L{\"u}thge and Christine Bergeron and Friedrich Kommoss and Thomas L{\"o}ning and Jaume Ordi and Sigrid Regauer and Ruediger Ridder",
year = "2011",
language = "English",
volume = "121",
pages = "505--509",
journal = "GYNECOL ONCOL",
issn = "0090-8258",
publisher = "Academic Press Inc.",
number = "3",

}

RIS

TY - JOUR

T1 - Triaging Pap cytology negative, HPV positive cervical cancer screening results with p16/Ki-67 Dual-stained cytology.

AU - Petry, K Ulrich

AU - Schmidt, Dietmar

AU - Scherbring, Sarah

AU - Luyten, Alexander

AU - Reinecke-Lüthge, Axel

AU - Bergeron, Christine

AU - Kommoss, Friedrich

AU - Löning, Thomas

AU - Ordi, Jaume

AU - Regauer, Sigrid

AU - Ridder, Ruediger

PY - 2011

Y1 - 2011

N2 - Testing for human papillomavirus (HPV) has been shown to increase the sensitivity and negative predictive value for detection of high-grade cervical intraepithelial neoplasia (CIN2+), either when used in conjunction with Pap cytology testing or alone. However, there is no satisfying clinical management algorithm for women testing Pap negative/HPV positive. We therefore evaluated the clinical utility of a novel dual biomarker-based approach (p16/Ki-67 Dual-stained cytology) for the identification of CIN2+ in women with Pap negative/HPV positive screening results, without the need to refer all women to immediate colposcopy.

AB - Testing for human papillomavirus (HPV) has been shown to increase the sensitivity and negative predictive value for detection of high-grade cervical intraepithelial neoplasia (CIN2+), either when used in conjunction with Pap cytology testing or alone. However, there is no satisfying clinical management algorithm for women testing Pap negative/HPV positive. We therefore evaluated the clinical utility of a novel dual biomarker-based approach (p16/Ki-67 Dual-stained cytology) for the identification of CIN2+ in women with Pap negative/HPV positive screening results, without the need to refer all women to immediate colposcopy.

KW - Adult

KW - Humans

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Cohort Studies

KW - Sensitivity and Specificity

KW - Vaginal Smears

KW - Neoplasm Proteins/metabolism

KW - Ki-67 Antigen/metabolism

KW - Staining and Labeling/methods

KW - Cervical Intraepithelial Neoplasia/metabolism/pathology/virology

KW - Papillomavirus Infections/metabolism/pathology/virology

KW - Uterine Cervical Neoplasms/metabolism/pathology/virology

KW - Adult

KW - Humans

KW - Aged

KW - Female

KW - Middle Aged

KW - Aged, 80 and over

KW - Cohort Studies

KW - Sensitivity and Specificity

KW - Vaginal Smears

KW - Neoplasm Proteins/metabolism

KW - Ki-67 Antigen/metabolism

KW - Staining and Labeling/methods

KW - Cervical Intraepithelial Neoplasia/metabolism/pathology/virology

KW - Papillomavirus Infections/metabolism/pathology/virology

KW - Uterine Cervical Neoplasms/metabolism/pathology/virology

M3 - SCORING: Journal article

VL - 121

SP - 505

EP - 509

JO - GYNECOL ONCOL

JF - GYNECOL ONCOL

SN - 0090-8258

IS - 3

M1 - 3

ER -