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Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration

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Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration. / Baroni, Lorena V; Rugilo, Carlos; Lubieniecki, Fabiana; Sampor, Claudia; Freytes, Candela; Nobre, Liana; Hansford, Jordan R; Malalasekera, Vajiranee S; Zapotocky, Michal; Dodgshun, Andrew; Martinez, Ofelia Cruz; La Madrid, Andres Morales; Lavarino, Cinzia; Suñol, Mariona; Rutkowski, Stefan; Schuller, Ulrich; Bouffet, Eric; Ramaswamy, Vijay; Alderete, Daniel.

In: PEDIATR BLOOD CANCER, Vol. 67, No. 12, 12.2020, p. e28627.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Baroni, LV, Rugilo, C, Lubieniecki, F, Sampor, C, Freytes, C, Nobre, L, Hansford, JR, Malalasekera, VS, Zapotocky, M, Dodgshun, A, Martinez, OC, La Madrid, AM, Lavarino, C, Suñol, M, Rutkowski, S, Schuller, U, Bouffet, E, Ramaswamy, V & Alderete, D 2020, 'Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration', PEDIATR BLOOD CANCER, vol. 67, no. 12, pp. e28627. https://doi.org/10.1002/pbc.28627

APA

Baroni, L. V., Rugilo, C., Lubieniecki, F., Sampor, C., Freytes, C., Nobre, L., Hansford, J. R., Malalasekera, V. S., Zapotocky, M., Dodgshun, A., Martinez, O. C., La Madrid, A. M., Lavarino, C., Suñol, M., Rutkowski, S., Schuller, U., Bouffet, E., Ramaswamy, V., & Alderete, D. (2020). Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration. PEDIATR BLOOD CANCER, 67(12), e28627. https://doi.org/10.1002/pbc.28627

Vancouver

Baroni LV, Rugilo C, Lubieniecki F, Sampor C, Freytes C, Nobre L et al. Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration. PEDIATR BLOOD CANCER. 2020 Dec;67(12):e28627. https://doi.org/10.1002/pbc.28627

Bibtex

@article{15543183ec0f4648a36e25031ac4cfd9,
title = "Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration",
abstract = "Central nervous system high-grade neuroepithelial tumor with MN1 alteration (CNS HGNET-MN1) is a rare recently described entity. Fourteen CNS HGNET-MN1 patients were identified using genome-wide methylation arrays/RT-PCR across seven institutions. All patients had surgery (gross total resection: 10; subtotal resection: four) as initial management followed by observation alone in three patients, followed by radiotherapy in eight patients (focal: five; craniospinal: two; CyberKnife: one) and systemic chemotherapy in three patients. Seven patients relapsed; five local and two metastatic, despite adjuvant radiotherapy, of which three died. Treatment of CNS HGNET-MN1 remains a major treatment challenge despite aggressive surgical resections and upfront radiotherapy, warranting new approaches to this rare malignancy.",
author = "Baroni, {Lorena V} and Carlos Rugilo and Fabiana Lubieniecki and Claudia Sampor and Candela Freytes and Liana Nobre and Hansford, {Jordan R} and Malalasekera, {Vajiranee S} and Michal Zapotocky and Andrew Dodgshun and Martinez, {Ofelia Cruz} and {La Madrid}, {Andres Morales} and Cinzia Lavarino and Mariona Su{\~n}ol and Stefan Rutkowski and Ulrich Schuller and Eric Bouffet and Vijay Ramaswamy and Daniel Alderete",
note = "{\textcopyright} 2020 Wiley Periodicals LLC.",
year = "2020",
month = dec,
doi = "10.1002/pbc.28627",
language = "English",
volume = "67",
pages = "e28627",
journal = "PEDIATR BLOOD CANCER",
issn = "1545-5009",
publisher = "Wiley-Liss Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - Treatment response of CNS high-grade neuroepithelial tumors with MN1 alteration

AU - Baroni, Lorena V

AU - Rugilo, Carlos

AU - Lubieniecki, Fabiana

AU - Sampor, Claudia

AU - Freytes, Candela

AU - Nobre, Liana

AU - Hansford, Jordan R

AU - Malalasekera, Vajiranee S

AU - Zapotocky, Michal

AU - Dodgshun, Andrew

AU - Martinez, Ofelia Cruz

AU - La Madrid, Andres Morales

AU - Lavarino, Cinzia

AU - Suñol, Mariona

AU - Rutkowski, Stefan

AU - Schuller, Ulrich

AU - Bouffet, Eric

AU - Ramaswamy, Vijay

AU - Alderete, Daniel

N1 - © 2020 Wiley Periodicals LLC.

PY - 2020/12

Y1 - 2020/12

N2 - Central nervous system high-grade neuroepithelial tumor with MN1 alteration (CNS HGNET-MN1) is a rare recently described entity. Fourteen CNS HGNET-MN1 patients were identified using genome-wide methylation arrays/RT-PCR across seven institutions. All patients had surgery (gross total resection: 10; subtotal resection: four) as initial management followed by observation alone in three patients, followed by radiotherapy in eight patients (focal: five; craniospinal: two; CyberKnife: one) and systemic chemotherapy in three patients. Seven patients relapsed; five local and two metastatic, despite adjuvant radiotherapy, of which three died. Treatment of CNS HGNET-MN1 remains a major treatment challenge despite aggressive surgical resections and upfront radiotherapy, warranting new approaches to this rare malignancy.

AB - Central nervous system high-grade neuroepithelial tumor with MN1 alteration (CNS HGNET-MN1) is a rare recently described entity. Fourteen CNS HGNET-MN1 patients were identified using genome-wide methylation arrays/RT-PCR across seven institutions. All patients had surgery (gross total resection: 10; subtotal resection: four) as initial management followed by observation alone in three patients, followed by radiotherapy in eight patients (focal: five; craniospinal: two; CyberKnife: one) and systemic chemotherapy in three patients. Seven patients relapsed; five local and two metastatic, despite adjuvant radiotherapy, of which three died. Treatment of CNS HGNET-MN1 remains a major treatment challenge despite aggressive surgical resections and upfront radiotherapy, warranting new approaches to this rare malignancy.

U2 - 10.1002/pbc.28627

DO - 10.1002/pbc.28627

M3 - SCORING: Journal article

C2 - 32959992

VL - 67

SP - e28627

JO - PEDIATR BLOOD CANCER

JF - PEDIATR BLOOD CANCER

SN - 1545-5009

IS - 12

ER -