Translating the molecular diversity of hepatocellular carcinoma into clinical practice

Abstract

Deciphering genomic diversity could improve clinical care for patients with hepatocellular carcinoma. Recently, our study group identified 161 putative driver genes and 2 new mutational signatures, and demonstrated that 28% of patients harbor targetable alterations. This could be the first promising step in the development of genome-based clinical trials.

Bibliographical data

Original languageEnglish
ISSN2372-3556
DOIs
Publication statusPublished - 07.2016
Externally publishedYes
PubMed 27652310