Translating the molecular diversity of hepatocellular carcinoma into clinical practice

Abstract

Deciphering genomic diversity could improve clinical care for patients with hepatocellular carcinoma. Recently, our study group identified 161 putative driver genes and 2 new mutational signatures, and demonstrated that 28% of patients harbor targetable alterations. This could be the first promising step in the development of genome-based clinical trials.

Bibliografische Daten

OriginalspracheEnglisch
ISSN2372-3556
DOIs
StatusVeröffentlicht - 07.2016
Extern publiziertJa
PubMed 27652310