Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis
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Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis : a case report. / Phillip, Veit; Berger, Hermann; Straub, Melanie; Saugel, Bernd; Treiber, Matthias; Einwächter, Henrik; Schmid, Roland M; Huber, Wolfgang.
In: ONKOLOGIE, Vol. 35, No. 6, 01.01.2012, p. 368-71.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis
T2 - a case report
AU - Phillip, Veit
AU - Berger, Hermann
AU - Straub, Melanie
AU - Saugel, Bernd
AU - Treiber, Matthias
AU - Einwächter, Henrik
AU - Schmid, Roland M
AU - Huber, Wolfgang
N1 - Copyright © 2012 S. Karger AG, Basel.
PY - 2012/1/1
Y1 - 2012/1/1
N2 - BACKGROUND: Primary myelofibrosis belongs to the group of myeloproliferative syndromes. Extramedullary hematopoiesis in the liver can lead to portal hypertension.PATIENT AND METHODS: We report a case of a patient with life-threatening, endoscopically not treatable bleeding from esophageal varices due to extramedullary hematopoiesis of the liver that was successfully treated with placement of a transjugular intrahepatic porto-systemic stent-shunt (TIPS).RESULTS: Therapy of variceal bleeding by TIPS insertion was successful. During a 29-month follow-up, no hepatic failure, hepatic encephalopathy, or further variceal bleeding episode occurred.CONCLUSION: TIPS placement is a well-established procedure for the treatment of complications due to portal hypertension mainly due to liver cirrhosis. This report illustrates that TIPS placement can also be a promising treatment option in patients with primary myelofibrosis and portal hypertension due to extramedullary hematopoiesis.
AB - BACKGROUND: Primary myelofibrosis belongs to the group of myeloproliferative syndromes. Extramedullary hematopoiesis in the liver can lead to portal hypertension.PATIENT AND METHODS: We report a case of a patient with life-threatening, endoscopically not treatable bleeding from esophageal varices due to extramedullary hematopoiesis of the liver that was successfully treated with placement of a transjugular intrahepatic porto-systemic stent-shunt (TIPS).RESULTS: Therapy of variceal bleeding by TIPS insertion was successful. During a 29-month follow-up, no hepatic failure, hepatic encephalopathy, or further variceal bleeding episode occurred.CONCLUSION: TIPS placement is a well-established procedure for the treatment of complications due to portal hypertension mainly due to liver cirrhosis. This report illustrates that TIPS placement can also be a promising treatment option in patients with primary myelofibrosis and portal hypertension due to extramedullary hematopoiesis.
KW - Aged
KW - Esophageal and Gastric Varices
KW - Gastrointestinal Hemorrhage
KW - Hematopoiesis, Extramedullary
KW - Humans
KW - Male
KW - Portasystemic Shunt, Transjugular Intrahepatic
KW - Primary Myelofibrosis
KW - Treatment Outcome
U2 - 10.1159/000338949
DO - 10.1159/000338949
M3 - SCORING: Journal article
C2 - 22722458
VL - 35
SP - 368
EP - 371
JO - ONKOLOGIE
JF - ONKOLOGIE
SN - 0378-584X
IS - 6
ER -