Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis

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Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis : a case report. / Phillip, Veit; Berger, Hermann; Straub, Melanie; Saugel, Bernd; Treiber, Matthias; Einwächter, Henrik; Schmid, Roland M; Huber, Wolfgang.

in: ONKOLOGIE, Jahrgang 35, Nr. 6, 01.01.2012, S. 368-71.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{ce5fb92e8dc74bafaeddd1c377fbed79,
title = "Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis: a case report",
abstract = "BACKGROUND: Primary myelofibrosis belongs to the group of myeloproliferative syndromes. Extramedullary hematopoiesis in the liver can lead to portal hypertension.PATIENT AND METHODS: We report a case of a patient with life-threatening, endoscopically not treatable bleeding from esophageal varices due to extramedullary hematopoiesis of the liver that was successfully treated with placement of a transjugular intrahepatic porto-systemic stent-shunt (TIPS).RESULTS: Therapy of variceal bleeding by TIPS insertion was successful. During a 29-month follow-up, no hepatic failure, hepatic encephalopathy, or further variceal bleeding episode occurred.CONCLUSION: TIPS placement is a well-established procedure for the treatment of complications due to portal hypertension mainly due to liver cirrhosis. This report illustrates that TIPS placement can also be a promising treatment option in patients with primary myelofibrosis and portal hypertension due to extramedullary hematopoiesis.",
keywords = "Aged, Esophageal and Gastric Varices, Gastrointestinal Hemorrhage, Hematopoiesis, Extramedullary, Humans, Male, Portasystemic Shunt, Transjugular Intrahepatic, Primary Myelofibrosis, Treatment Outcome",
author = "Veit Phillip and Hermann Berger and Melanie Straub and Bernd Saugel and Matthias Treiber and Henrik Einw{\"a}chter and Schmid, {Roland M} and Wolfgang Huber",
note = "Copyright {\textcopyright} 2012 S. Karger AG, Basel.",
year = "2012",
month = jan,
day = "1",
doi = "10.1159/000338949",
language = "English",
volume = "35",
pages = "368--71",
journal = "ONKOLOGIE",
issn = "0378-584X",
publisher = "S. Karger AG",
number = "6",

}

RIS

TY - JOUR

T1 - Transjugular intrahepatic porto-systemic stent-shunt for therapy of bleeding esophageal varices due to extramedullary hematopoiesis in primary myelofibrosis

T2 - a case report

AU - Phillip, Veit

AU - Berger, Hermann

AU - Straub, Melanie

AU - Saugel, Bernd

AU - Treiber, Matthias

AU - Einwächter, Henrik

AU - Schmid, Roland M

AU - Huber, Wolfgang

N1 - Copyright © 2012 S. Karger AG, Basel.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - BACKGROUND: Primary myelofibrosis belongs to the group of myeloproliferative syndromes. Extramedullary hematopoiesis in the liver can lead to portal hypertension.PATIENT AND METHODS: We report a case of a patient with life-threatening, endoscopically not treatable bleeding from esophageal varices due to extramedullary hematopoiesis of the liver that was successfully treated with placement of a transjugular intrahepatic porto-systemic stent-shunt (TIPS).RESULTS: Therapy of variceal bleeding by TIPS insertion was successful. During a 29-month follow-up, no hepatic failure, hepatic encephalopathy, or further variceal bleeding episode occurred.CONCLUSION: TIPS placement is a well-established procedure for the treatment of complications due to portal hypertension mainly due to liver cirrhosis. This report illustrates that TIPS placement can also be a promising treatment option in patients with primary myelofibrosis and portal hypertension due to extramedullary hematopoiesis.

AB - BACKGROUND: Primary myelofibrosis belongs to the group of myeloproliferative syndromes. Extramedullary hematopoiesis in the liver can lead to portal hypertension.PATIENT AND METHODS: We report a case of a patient with life-threatening, endoscopically not treatable bleeding from esophageal varices due to extramedullary hematopoiesis of the liver that was successfully treated with placement of a transjugular intrahepatic porto-systemic stent-shunt (TIPS).RESULTS: Therapy of variceal bleeding by TIPS insertion was successful. During a 29-month follow-up, no hepatic failure, hepatic encephalopathy, or further variceal bleeding episode occurred.CONCLUSION: TIPS placement is a well-established procedure for the treatment of complications due to portal hypertension mainly due to liver cirrhosis. This report illustrates that TIPS placement can also be a promising treatment option in patients with primary myelofibrosis and portal hypertension due to extramedullary hematopoiesis.

KW - Aged

KW - Esophageal and Gastric Varices

KW - Gastrointestinal Hemorrhage

KW - Hematopoiesis, Extramedullary

KW - Humans

KW - Male

KW - Portasystemic Shunt, Transjugular Intrahepatic

KW - Primary Myelofibrosis

KW - Treatment Outcome

U2 - 10.1159/000338949

DO - 10.1159/000338949

M3 - SCORING: Journal article

C2 - 22722458

VL - 35

SP - 368

EP - 371

JO - ONKOLOGIE

JF - ONKOLOGIE

SN - 0378-584X

IS - 6

ER -