TP53 and Prognosis in mCRPC Survival: Biology or Coincidence?
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Abstract
Cell-free circulating tumor DNA (ctDNA) or circulating tumor cell (CTC) assays are potentially powerful in the treatment of metastatic castration-resistant prostate cancer (mCRPC). A new study suggests that mutation of TP53 supersedes AR in predicting mCRPC survival. A role for TP53 mutation as a driver for mCRPC remains unexplored.See related article by De Laere et al., p. 1766.
Bibliographical data
Original language | English |
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ISSN | 1078-0432 |
DOIs | |
Publication status | Published - 15.03.2019 |
PubMed | 30610102 |
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