TP53 and Prognosis in mCRPC Survival: Biology or Coincidence?

Beteiligte Einrichtungen

Abstract

Cell-free circulating tumor DNA (ctDNA) or circulating tumor cell (CTC) assays are potentially powerful in the treatment of metastatic castration-resistant prostate cancer (mCRPC). A new study suggests that mutation of TP53 supersedes AR in predicting mCRPC survival. A role for TP53 mutation as a driver for mCRPC remains unexplored.See related article by De Laere et al., p. 1766.

Bibliografische Daten

OriginalspracheEnglisch
ISSN1078-0432
DOIs
StatusVeröffentlicht - 15.03.2019

Anmerkungen des Dekanats

©2019 American Association for Cancer Research.

PubMed 30610102