Toxicity screening of mouthwashes in the pollen tube growth test: safety assessment of recommended dilutions of twenty brands

Udo Kristen; Reinhard E Friedrich

Toxicity screening of mouthwashes in the pollen tube growth test

Standard

Toxicity screening of mouthwashes in the pollen tube growth test : safety assessment of recommended dilutions of twenty brands. / Kristen, Udo; Friedrich, Reinhard E.

In: IN VIVO, Vol. 18, No. 6, 2005, p. 803-7.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Kristen, U & Friedrich, RE 2005, 'Toxicity screening of mouthwashes in the pollen tube growth test: safety assessment of recommended dilutions of twenty brands', IN VIVO, vol. 18, no. 6, pp. 803-7.

APA

Kristen, U., & Friedrich, R. E. (2005). Toxicity screening of mouthwashes in the pollen tube growth test: safety assessment of recommended dilutions of twenty brands. IN VIVO, 18(6), 803-7.

Vancouver

Kristen U, Friedrich RE. Toxicity screening of mouthwashes in the pollen tube growth test: safety assessment of recommended dilutions of twenty brands. IN VIVO. 2005;18(6):803-7.

Bibtex

@article{2196fcd74e4041aca0f0ce470d67a022,

title = "Toxicity screening of mouthwashes in the pollen tube growth test: safety assessment of recommended dilutions of twenty brands",

abstract = "The question of whether mouthwash dilutions, recommended by the producers, contribute to irritation of the oral mucosa was examined. Twenty frequently used mouthwash brands were examined by the pollen tube growth test, an alternative in vitro method for the irritation assessment of ingredients of cosmetic formulations. The test is based on the photometric quantification of pollen tube growth inhibition. This parameter is expressed by IC50 values which characterize the cytotoxic potency of a product. The IC50s clearly revealed that none of the tested mouthwashes should cause acute irritation if used at the recommended dilution. However, 4 to 5 of the mouthwashes could probably irritate the oral mucosa acutely, when used in the form of the original producer concentrations.",

keywords = "Animal Testing Alternatives, Dose-Response Relationship, Drug, Flowers, Mouthwashes, Tobacco, Toxicity Tests",

author = "Udo Kristen and Friedrich, {Reinhard E}",

year = "2005",

language = "English",

volume = "18",

pages = "803--7",

journal = "IN VIVO",

issn = "0258-851X",

publisher = "International Institute of Anticancer Research",

number = "6",

}

RIS

TY - JOUR

T1 - Toxicity screening of mouthwashes in the pollen tube growth test

T2 - safety assessment of recommended dilutions of twenty brands

AU - Kristen, Udo

AU - Friedrich, Reinhard E

PY - 2005

Y1 - 2005

N2 - The question of whether mouthwash dilutions, recommended by the producers, contribute to irritation of the oral mucosa was examined. Twenty frequently used mouthwash brands were examined by the pollen tube growth test, an alternative in vitro method for the irritation assessment of ingredients of cosmetic formulations. The test is based on the photometric quantification of pollen tube growth inhibition. This parameter is expressed by IC50 values which characterize the cytotoxic potency of a product. The IC50s clearly revealed that none of the tested mouthwashes should cause acute irritation if used at the recommended dilution. However, 4 to 5 of the mouthwashes could probably irritate the oral mucosa acutely, when used in the form of the original producer concentrations.

AB - The question of whether mouthwash dilutions, recommended by the producers, contribute to irritation of the oral mucosa was examined. Twenty frequently used mouthwash brands were examined by the pollen tube growth test, an alternative in vitro method for the irritation assessment of ingredients of cosmetic formulations. The test is based on the photometric quantification of pollen tube growth inhibition. This parameter is expressed by IC50 values which characterize the cytotoxic potency of a product. The IC50s clearly revealed that none of the tested mouthwashes should cause acute irritation if used at the recommended dilution. However, 4 to 5 of the mouthwashes could probably irritate the oral mucosa acutely, when used in the form of the original producer concentrations.

KW - Animal Testing Alternatives

KW - Dose-Response Relationship, Drug

KW - Flowers

KW - Mouthwashes

KW - Tobacco

KW - Toxicity Tests

M3 - SCORING: Journal article

C2 - 15646824

VL - 18

SP - 803

EP - 807

JO - IN VIVO

JF - IN VIVO

SN - 0258-851X

IS - 6

ER -