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TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.

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TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling. / Brase, Jan C; Johannes, Marc; Mannsperger, Heiko; Fälth, Maria; Metzger, Jennifer; Kacprzyk, Lukasz A; Andrasiuk, Tatjana; Gade, Stephan; Meister, Michael; Sirma, Hüseyin; Sauter, Guido; Simon, Ronald; Schlomm, Thorsten; Beissbarth, Tim; Korf, Ulrike; Kuner, Ruprecht; Sültmann, Holger.

In: BMC CANCER, Vol. 11, 2011, p. 507.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Brase, JC, Johannes, M, Mannsperger, H, Fälth, M, Metzger, J, Kacprzyk, LA, Andrasiuk, T, Gade, S, Meister, M, Sirma, H, Sauter, G, Simon, R, Schlomm, T, Beissbarth, T, Korf, U, Kuner, R & Sültmann, H 2011, 'TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.', BMC CANCER, vol. 11, pp. 507. https://doi.org/10.1186/1471-2407-11-507

APA

Brase, J. C., Johannes, M., Mannsperger, H., Fälth, M., Metzger, J., Kacprzyk, L. A., Andrasiuk, T., Gade, S., Meister, M., Sirma, H., Sauter, G., Simon, R., Schlomm, T., Beissbarth, T., Korf, U., Kuner, R., & Sültmann, H. (2011). TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling. BMC CANCER, 11, 507. https://doi.org/10.1186/1471-2407-11-507

Vancouver

Brase JC, Johannes M, Mannsperger H, Fälth M, Metzger J, Kacprzyk LA et al. TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling. BMC CANCER. 2011;11:507. https://doi.org/10.1186/1471-2407-11-507

Bibtex

@article{1ae16108c44e48ad8bd824f31cce1cb0,
title = "TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.",
abstract = "TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion seems to be a critical event in prostate cancer, the precise functional role in cancer development and progression is still unclear.",
keywords = "Humans, Male, Gene Expression Regulation, Gene Fusion, Polymerase Chain Reaction, Molecular Targeted Therapy, Prostatectomy, *Gene Expression Profiling, Oncogene Proteins, Fusion/*genetics/metabolism, Prostate/metabolism, Prostatic Neoplasms/*genetics/metabolism/therapy, RNA, Neoplasm/analysis, Transforming Growth Factor beta/*genetics/metabolism, Tumor Markers, Biological/*genetics/metabolism, Humans, Male, Gene Expression Regulation, Gene Fusion, Polymerase Chain Reaction, Molecular Targeted Therapy, Prostatectomy, *Gene Expression Profiling, Oncogene Proteins, Fusion/*genetics/metabolism, Prostate/metabolism, Prostatic Neoplasms/*genetics/metabolism/therapy, RNA, Neoplasm/analysis, Transforming Growth Factor beta/*genetics/metabolism, Tumor Markers, Biological/*genetics/metabolism",
author = "Brase, {Jan C} and Marc Johannes and Heiko Mannsperger and Maria F{\"a}lth and Jennifer Metzger and Kacprzyk, {Lukasz A} and Tatjana Andrasiuk and Stephan Gade and Michael Meister and H{\"u}seyin Sirma and Guido Sauter and Ronald Simon and Thorsten Schlomm and Tim Beissbarth and Ulrike Korf and Ruprecht Kuner and Holger S{\"u}ltmann",
year = "2011",
doi = "10.1186/1471-2407-11-507",
language = "English",
volume = "11",
pages = "507",
journal = "BMC CANCER",
issn = "1471-2407",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.

AU - Brase, Jan C

AU - Johannes, Marc

AU - Mannsperger, Heiko

AU - Fälth, Maria

AU - Metzger, Jennifer

AU - Kacprzyk, Lukasz A

AU - Andrasiuk, Tatjana

AU - Gade, Stephan

AU - Meister, Michael

AU - Sirma, Hüseyin

AU - Sauter, Guido

AU - Simon, Ronald

AU - Schlomm, Thorsten

AU - Beissbarth, Tim

AU - Korf, Ulrike

AU - Kuner, Ruprecht

AU - Sültmann, Holger

PY - 2011

Y1 - 2011

N2 - TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion seems to be a critical event in prostate cancer, the precise functional role in cancer development and progression is still unclear.

AB - TMPRSS2-ERG gene fusions occur in about 50% of all prostate cancer cases and represent promising markers for molecular subtyping. Although TMPRSS2-ERG fusion seems to be a critical event in prostate cancer, the precise functional role in cancer development and progression is still unclear.

KW - Humans

KW - Male

KW - Gene Expression Regulation

KW - Gene Fusion

KW - Polymerase Chain Reaction

KW - Molecular Targeted Therapy

KW - Prostatectomy

KW - Gene Expression Profiling

KW - Oncogene Proteins, Fusion/genetics/metabolism

KW - Prostate/metabolism

KW - Prostatic Neoplasms/genetics/metabolism/therapy

KW - RNA, Neoplasm/analysis

KW - Transforming Growth Factor beta/genetics/metabolism

KW - Tumor Markers, Biological/genetics/metabolism

KW - Humans

KW - Male

KW - Gene Expression Regulation

KW - Gene Fusion

KW - Polymerase Chain Reaction

KW - Molecular Targeted Therapy

KW - Prostatectomy

KW - Gene Expression Profiling

KW - Oncogene Proteins, Fusion/genetics/metabolism

KW - Prostate/metabolism

KW - Prostatic Neoplasms/genetics/metabolism/therapy

KW - RNA, Neoplasm/analysis

KW - Transforming Growth Factor beta/genetics/metabolism

KW - Tumor Markers, Biological/genetics/metabolism

U2 - 10.1186/1471-2407-11-507

DO - 10.1186/1471-2407-11-507

M3 - SCORING: Journal article

VL - 11

SP - 507

JO - BMC CANCER

JF - BMC CANCER

SN - 1471-2407

ER -