Three suicide attempts with moclobemide.

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Three suicide attempts with moclobemide. / Iwersen-Bergmann, Stefanie; Schmoldt, A.

In: J TOXICOL-CLIN TOXIC, Vol. 34, No. 2, 2, 1996, p. 223-225.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Iwersen-Bergmann, S & Schmoldt, A 1996, 'Three suicide attempts with moclobemide.', J TOXICOL-CLIN TOXIC, vol. 34, no. 2, 2, pp. 223-225. <http://www.ncbi.nlm.nih.gov/pubmed/8618258?dopt=Citation>

APA

Vancouver

Iwersen-Bergmann S, Schmoldt A. Three suicide attempts with moclobemide. J TOXICOL-CLIN TOXIC. 1996;34(2):223-225. 2.

Bibtex

@article{6a586b57cdfd436f90b3442fdb817af5,
title = "Three suicide attempts with moclobemide.",
abstract = "OBJECTIVE: To report plasma moclobemide, course and outcome of two cases of overdose with moclobemide alone and one case of combined ingestion of moclobemide and clomipramide. METHODS: Moclobemide identification and quantification was achieved by gas chromatography-mass spectrometry after alkaline extraction. CASE REPORTS: In case 1, plasma moclobemide was 2.8 mg/L with 1.8 mg/L clomipramide; in case 2, 18 mg/L; in case 3 60.9 mg/L and 4.6 mg/L 12 hours later. None of the patients showed serious effects during 24 hours of observation. Plasma moclobemide at 10 to 30 times therapeutic was not associated with major toxic effects. Moclobemide seems to be considerably less toxic than tricyclic antidepressants.",
keywords = "Humans, Female, Middle Aged, Drug Interactions, Gas Chromatography-Mass Spectrometry, Antidepressive Agents, Tricyclic/poisoning, Benzamides/blood/*poisoning, Clomipramine/poisoning, Drug Overdose, Moclobemide, Monoamine Oxidase Inhibitors/blood/*poisoning, *Suicide, Attempted, Humans, Female, Middle Aged, Drug Interactions, Gas Chromatography-Mass Spectrometry, Antidepressive Agents, Tricyclic/poisoning, Benzamides/blood/*poisoning, Clomipramine/poisoning, Drug Overdose, Moclobemide, Monoamine Oxidase Inhibitors/blood/*poisoning, *Suicide, Attempted",
author = "Stefanie Iwersen-Bergmann and A Schmoldt",
year = "1996",
language = "English",
volume = "34",
pages = "223--225",
number = "2",

}

RIS

TY - JOUR

T1 - Three suicide attempts with moclobemide.

AU - Iwersen-Bergmann, Stefanie

AU - Schmoldt, A

PY - 1996

Y1 - 1996

N2 - OBJECTIVE: To report plasma moclobemide, course and outcome of two cases of overdose with moclobemide alone and one case of combined ingestion of moclobemide and clomipramide. METHODS: Moclobemide identification and quantification was achieved by gas chromatography-mass spectrometry after alkaline extraction. CASE REPORTS: In case 1, plasma moclobemide was 2.8 mg/L with 1.8 mg/L clomipramide; in case 2, 18 mg/L; in case 3 60.9 mg/L and 4.6 mg/L 12 hours later. None of the patients showed serious effects during 24 hours of observation. Plasma moclobemide at 10 to 30 times therapeutic was not associated with major toxic effects. Moclobemide seems to be considerably less toxic than tricyclic antidepressants.

AB - OBJECTIVE: To report plasma moclobemide, course and outcome of two cases of overdose with moclobemide alone and one case of combined ingestion of moclobemide and clomipramide. METHODS: Moclobemide identification and quantification was achieved by gas chromatography-mass spectrometry after alkaline extraction. CASE REPORTS: In case 1, plasma moclobemide was 2.8 mg/L with 1.8 mg/L clomipramide; in case 2, 18 mg/L; in case 3 60.9 mg/L and 4.6 mg/L 12 hours later. None of the patients showed serious effects during 24 hours of observation. Plasma moclobemide at 10 to 30 times therapeutic was not associated with major toxic effects. Moclobemide seems to be considerably less toxic than tricyclic antidepressants.

KW - Humans

KW - Female

KW - Middle Aged

KW - Drug Interactions

KW - Gas Chromatography-Mass Spectrometry

KW - Antidepressive Agents, Tricyclic/poisoning

KW - Benzamides/blood/poisoning

KW - Clomipramine/poisoning

KW - Drug Overdose

KW - Moclobemide

KW - Monoamine Oxidase Inhibitors/blood/poisoning

KW - Suicide, Attempted

KW - Humans

KW - Female

KW - Middle Aged

KW - Drug Interactions

KW - Gas Chromatography-Mass Spectrometry

KW - Antidepressive Agents, Tricyclic/poisoning

KW - Benzamides/blood/poisoning

KW - Clomipramine/poisoning

KW - Drug Overdose

KW - Moclobemide

KW - Monoamine Oxidase Inhibitors/blood/poisoning

KW - Suicide, Attempted

M3 - SCORING: Journal article

VL - 34

SP - 223

EP - 225

IS - 2

M1 - 2

ER -