The T393C polymorphism of GNAS1 is a predictor for relapse and survival in resectable non-small cell lung cancer.
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Abstract
The GNAS1 T393C single nucleotide polymorphism (T393C-SNP) correlates with G?s mRNA stability and protein expression and augmented apoptosis. Genetic germ line variations as stable and reproducible markers potentially serve as prognostic marker in oncology. The aim of this study was to evaluate the potential prognostic value of T393C-SNP in complete resected non-small cell lung cancer (NSCLC).
Bibliographical data
| Original language | English |
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| Article number | 2 |
| ISSN | 0169-5002 |
| Publication status | Published - 2013 |
| pubmed | 23201296 |
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