The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib

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The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib. / Albers, C; Leischner, H; Verbeek, M; Yu, C; Illert, A L; Peschel, C; von Bubnoff, N; Duyster, J.

In: LEUKEMIA, Vol. 27, No. 6, 06.2013, p. 1416-8.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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@article{d28f48a9e5cd41efb9bc7cc96caa2ad5,
title = "The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib",
keywords = "Antineoplastic Agents, Benzothiazoles, Drug Resistance, Neoplasm, Female, Humans, Indoles, Leukemia, Myeloid, Acute, Middle Aged, Mutation, Phenylurea Compounds, Pyrroles, Staurosporine, fms-Like Tyrosine Kinase 3, Case Reports, Letter",
author = "C Albers and H Leischner and M Verbeek and C Yu and Illert, {A L} and C Peschel and {von Bubnoff}, N and J Duyster",
year = "2013",
month = jun,
doi = "10.1038/leu.2013.14",
language = "English",
volume = "27",
pages = "1416--8",
journal = "LEUKEMIA",
issn = "0887-6924",
publisher = "NATURE PUBLISHING GROUP",
number = "6",

}

RIS

TY - JOUR

T1 - The secondary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD+ AML but retains in vitro sensitivity to PKC412 and Sunitinib

AU - Albers, C

AU - Leischner, H

AU - Verbeek, M

AU - Yu, C

AU - Illert, A L

AU - Peschel, C

AU - von Bubnoff, N

AU - Duyster, J

PY - 2013/6

Y1 - 2013/6

KW - Antineoplastic Agents

KW - Benzothiazoles

KW - Drug Resistance, Neoplasm

KW - Female

KW - Humans

KW - Indoles

KW - Leukemia, Myeloid, Acute

KW - Middle Aged

KW - Mutation

KW - Phenylurea Compounds

KW - Pyrroles

KW - Staurosporine

KW - fms-Like Tyrosine Kinase 3

KW - Case Reports

KW - Letter

U2 - 10.1038/leu.2013.14

DO - 10.1038/leu.2013.14

M3 - SCORING: Journal article

C2 - 23392356

VL - 27

SP - 1416

EP - 1418

JO - LEUKEMIA

JF - LEUKEMIA

SN - 0887-6924

IS - 6

ER -