Research ExplorerPublicationsThe Rare Occurrence of the Translocation t(8;14) in Chronic ...

The Rare Occurrence of the Translocation t(8;14) in Chronic Lymphatic Leukemia: Case Report and Review of the Literature

Standard

The Rare Occurrence of the Translocation t(8;14) in Chronic Lymphatic Leukemia: Case Report and Review of the Literature. / Coym, Anja; Janjetovic, Snjezana; Bokemeyer, Carsten; Fiedler, Walter.

In: Ann Hematol Oncol, Vol. 2, No. 5, 03.06.2015, p. 1039.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Coym, A, Janjetovic, S, Bokemeyer, C & Fiedler, W 2015, 'The Rare Occurrence of the Translocation t(8;14) in Chronic Lymphatic Leukemia: Case Report and Review of the Literature', Ann Hematol Oncol, vol. 2, no. 5, pp. 1039.

APA

Coym, A., Janjetovic, S., Bokemeyer, C., & Fiedler, W. (2015). The Rare Occurrence of the Translocation t(8;14) in Chronic Lymphatic Leukemia: Case Report and Review of the Literature. Ann Hematol Oncol, 2(5), 1039.

Vancouver

Coym A, Janjetovic S, Bokemeyer C, Fiedler W. The Rare Occurrence of the Translocation t(8;14) in Chronic Lymphatic Leukemia: Case Report and Review of the Literature. Ann Hematol Oncol. 2015 Jun 3;2(5):1039.

Bibtex

@article{5bcc30db688748d18ac02723ab981fa7,
title = "The Rare Occurrence of the Translocation t(8;14) in Chronic Lymphatic Leukemia: Case Report and Review of the Literature",
abstract = "Genomic aberrations in Chronic Lymphatic Leukemia (CLL) are importantprognostic factors of disease progression and survival and contribute to thetreatment decisions and follow-up. The most common chromosomal aberrationsdetected in CLL are deletions of 13q14, 11q22, 17p13 and trisomy 12. Deletions17p13.1 and 11q22.3 are strong predictors of poor survival. We report on arare case of CLL exhibiting the MYC translocation t(8,14)(q24;q32), which is aconsistent cytogenetic finding of Burkitt lymphoma. This translocation in CLLmostly appears with other chromosomal abnormalities and is associated withmore aggressive disease behavior. After review of the literature, the outcomeof CLL patients with MYC translocation is discussed, where prognosis is oftenpoor.",
author = "Anja Coym and Snjezana Janjetovic and Carsten Bokemeyer and Walter Fiedler",
year = "2015",
month = jun,
day = "3",
language = "English",
volume = "2",
pages = "1039",
journal = "Ann Hematol Oncol",
issn = "2375-7965",
publisher = "Austin Publishing Group",
number = "5",

}

RIS

TY - JOUR

T1 - The Rare Occurrence of the Translocation t(8;14) in Chronic Lymphatic Leukemia: Case Report and Review of the Literature

AU - Coym, Anja

AU - Janjetovic, Snjezana

AU - Bokemeyer, Carsten

AU - Fiedler, Walter

PY - 2015/6/3

Y1 - 2015/6/3

N2 - Genomic aberrations in Chronic Lymphatic Leukemia (CLL) are importantprognostic factors of disease progression and survival and contribute to thetreatment decisions and follow-up. The most common chromosomal aberrationsdetected in CLL are deletions of 13q14, 11q22, 17p13 and trisomy 12. Deletions17p13.1 and 11q22.3 are strong predictors of poor survival. We report on arare case of CLL exhibiting the MYC translocation t(8,14)(q24;q32), which is aconsistent cytogenetic finding of Burkitt lymphoma. This translocation in CLLmostly appears with other chromosomal abnormalities and is associated withmore aggressive disease behavior. After review of the literature, the outcomeof CLL patients with MYC translocation is discussed, where prognosis is oftenpoor.

AB - Genomic aberrations in Chronic Lymphatic Leukemia (CLL) are importantprognostic factors of disease progression and survival and contribute to thetreatment decisions and follow-up. The most common chromosomal aberrationsdetected in CLL are deletions of 13q14, 11q22, 17p13 and trisomy 12. Deletions17p13.1 and 11q22.3 are strong predictors of poor survival. We report on arare case of CLL exhibiting the MYC translocation t(8,14)(q24;q32), which is aconsistent cytogenetic finding of Burkitt lymphoma. This translocation in CLLmostly appears with other chromosomal abnormalities and is associated withmore aggressive disease behavior. After review of the literature, the outcomeof CLL patients with MYC translocation is discussed, where prognosis is oftenpoor.

M3 - SCORING: Journal article

VL - 2

SP - 1039

JO - Ann Hematol Oncol

JF - Ann Hematol Oncol

SN - 2375-7965

IS - 5

ER -