The putative oncogene CPI-17 is up-regulated in schwannoma
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The putative oncogene CPI-17 is up-regulated in schwannoma. / Hagel, Christian; Dornblut, Carsten; Schulz, Alexander; Wiehl, Ulrike; Friedrich, Reinhard E; Huckhagel, Torge; Mautner, Victor-Felix; Morrison, Helen.
In: NEUROPATH APPL NEURO, Vol. 42, No. 7, 12.2016, p. 664-668.Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review
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TY - JOUR
T1 - The putative oncogene CPI-17 is up-regulated in schwannoma
AU - Hagel, Christian
AU - Dornblut, Carsten
AU - Schulz, Alexander
AU - Wiehl, Ulrike
AU - Friedrich, Reinhard E
AU - Huckhagel, Torge
AU - Mautner, Victor-Felix
AU - Morrison, Helen
N1 - Document Type:Letter
PY - 2016/12
Y1 - 2016/12
N2 - CPI-17 (PPP1R14A protein phosphatase 1 regulatory inhibitor subunit 14A, 17 kDa) was previously described to act as an oncoprotein in the merlin pathway. The myosin phosphatase and its substrate merlin are part of a tumour suppressor cascade that can be blocked in two ways; by mutation of the NF2 gene encoding the tumour suppressor protein merlin and by up-regulation of the specific myosin phosphatase inhibitor, CPI-17. This article is protected by copyright. All rights reserved.
AB - CPI-17 (PPP1R14A protein phosphatase 1 regulatory inhibitor subunit 14A, 17 kDa) was previously described to act as an oncoprotein in the merlin pathway. The myosin phosphatase and its substrate merlin are part of a tumour suppressor cascade that can be blocked in two ways; by mutation of the NF2 gene encoding the tumour suppressor protein merlin and by up-regulation of the specific myosin phosphatase inhibitor, CPI-17. This article is protected by copyright. All rights reserved.
U2 - 10.1111/nan.12330
DO - 10.1111/nan.12330
M3 - SCORING: Journal article
C2 - 27248983
VL - 42
SP - 664
EP - 668
JO - NEUROPATH APPL NEURO
JF - NEUROPATH APPL NEURO
SN - 0305-1846
IS - 7
ER -