The natural and the inducible interleukin (IL)-17-producing γδ T cells

Yueh-hsiu Chien; Xun Zeng; Immo Prinz

doi:10.1016/j.it.2012.11.004

The natural and the inducible interleukin (IL)-17-producing γδ T cells

Standard

The natural and the inducible interleukin (IL)-17-producing γδ T cells. / Chien, Yueh-hsiu; Zeng, Xun; Prinz, Immo.

In: TRENDS IMMUNOL, Vol. 34, No. 4, 04.2013, p. 151-4.

Research output: SCORING: Contribution to journal › SCORING: Review article › Research

Harvard

Chien, Y, Zeng, X & Prinz, I 2013, 'The natural and the inducible interleukin (IL)-17-producing γδ T cells', TRENDS IMMUNOL, vol. 34, no. 4, pp. 151-4. https://doi.org/10.1016/j.it.2012.11.004

APA

Chien, Y., Zeng, X., & Prinz, I. (2013). The natural and the inducible interleukin (IL)-17-producing γδ T cells. TRENDS IMMUNOL, 34(4), 151-4. https://doi.org/10.1016/j.it.2012.11.004

Vancouver

Chien Y, Zeng X, Prinz I. The natural and the inducible interleukin (IL)-17-producing γδ T cells. TRENDS IMMUNOL. 2013 Apr;34(4):151-4. https://doi.org/10.1016/j.it.2012.11.004

Bibtex

@article{afc44864242348bbbf7cb953a0766d49,

title = "The natural and the inducible interleukin (IL)-17-producing γδ T cells",

abstract = "γδ T cells are the major initial interleukin (IL)-17 producers in acute infections. Recent studies have indicated that some γδ T cells have IL-17-producing capabilities without explicit induction of an immune response. They are preferentially localized in barrier tissues and are likely to originate from fetal γδ thymocytes. In addition, γδ T cells present in the secondary lymphoid organs will mature and differentiate to produce IL-17 after antigen encounter in an immune response. Based on these studies, we propose that there are two different sets of IL-17-producing γδ T cells (Tγδ17) referred to as the 'natural' and the 'inducible' Tγδ17 cells. This review focuses on recent publications leading to the delineation of these two types of cells and their implied roles in host immune defense.",

keywords = "Acute Disease, Animals, Cell Differentiation/immunology, Humans, Immunity, Cellular, Infections/immunology, Interleukin-17/immunology, Receptors, Antigen, T-Cell, gamma-delta/immunology, T-Lymphocyte Subsets/immunology, Th17 Cells/immunology",

author = "Yueh-hsiu Chien and Xun Zeng and Immo Prinz",

year = "2013",

month = apr,

doi = "10.1016/j.it.2012.11.004",

language = "English",

volume = "34",

pages = "151--4",

journal = "TRENDS IMMUNOL",

issn = "1471-4906",

publisher = "Elsevier Limited",

number = "4",

}

RIS

TY - JOUR

T1 - The natural and the inducible interleukin (IL)-17-producing γδ T cells

AU - Chien, Yueh-hsiu

AU - Zeng, Xun

AU - Prinz, Immo

PY - 2013/4

Y1 - 2013/4

N2 - γδ T cells are the major initial interleukin (IL)-17 producers in acute infections. Recent studies have indicated that some γδ T cells have IL-17-producing capabilities without explicit induction of an immune response. They are preferentially localized in barrier tissues and are likely to originate from fetal γδ thymocytes. In addition, γδ T cells present in the secondary lymphoid organs will mature and differentiate to produce IL-17 after antigen encounter in an immune response. Based on these studies, we propose that there are two different sets of IL-17-producing γδ T cells (Tγδ17) referred to as the 'natural' and the 'inducible' Tγδ17 cells. This review focuses on recent publications leading to the delineation of these two types of cells and their implied roles in host immune defense.

AB - γδ T cells are the major initial interleukin (IL)-17 producers in acute infections. Recent studies have indicated that some γδ T cells have IL-17-producing capabilities without explicit induction of an immune response. They are preferentially localized in barrier tissues and are likely to originate from fetal γδ thymocytes. In addition, γδ T cells present in the secondary lymphoid organs will mature and differentiate to produce IL-17 after antigen encounter in an immune response. Based on these studies, we propose that there are two different sets of IL-17-producing γδ T cells (Tγδ17) referred to as the 'natural' and the 'inducible' Tγδ17 cells. This review focuses on recent publications leading to the delineation of these two types of cells and their implied roles in host immune defense.

KW - Acute Disease

KW - Animals

KW - Cell Differentiation/immunology

KW - Humans

KW - Immunity, Cellular

KW - Infections/immunology

KW - Interleukin-17/immunology

KW - Receptors, Antigen, T-Cell, gamma-delta/immunology

KW - T-Lymphocyte Subsets/immunology

KW - Th17 Cells/immunology

U2 - 10.1016/j.it.2012.11.004

DO - 10.1016/j.it.2012.11.004

M3 - SCORING: Review article

C2 - 23266231

VL - 34

SP - 151

EP - 154

JO - TRENDS IMMUNOL

JF - TRENDS IMMUNOL

SN - 1471-4906

IS - 4

ER -