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The murine AE4 promoter predominantly drives type B intercalated cell specific transcription.

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The murine AE4 promoter predominantly drives type B intercalated cell specific transcription. / Hentschke, Moritz; Hentschke, Suna; Borgmeyer, Uwe; Hübner, Christian; Kurth, Ingo.

In: HISTOCHEM CELL BIOL, 2009.

Research output: SCORING: Contribution to journal › SCORING: Journal article › Research › peer-review

Harvard

Hentschke, M, Hentschke, S, Borgmeyer, U, Hübner, C & Kurth, I 2009, 'The murine AE4 promoter predominantly drives type B intercalated cell specific transcription.', HISTOCHEM CELL BIOL. <http://www.ncbi.nlm.nih.gov/pubmed/19544066?dopt=Citation>

APA

Hentschke, M., Hentschke, S., Borgmeyer, U., Hübner, C., & Kurth, I. (2009). The murine AE4 promoter predominantly drives type B intercalated cell specific transcription. HISTOCHEM CELL BIOL. http://www.ncbi.nlm.nih.gov/pubmed/19544066?dopt=Citation

Vancouver

Hentschke M, Hentschke S, Borgmeyer U, Hübner C, Kurth I. The murine AE4 promoter predominantly drives type B intercalated cell specific transcription. HISTOCHEM CELL BIOL. 2009.

Bibtex

@article{247ef9688abe4b21ae00131e5de2aef8,
title = "The murine AE4 promoter predominantly drives type B intercalated cell specific transcription.",
abstract = "AE4 is an anion exchanger almost exclusively expressed in the collecting ducts of the kidney. This very restricted expression prompted us to analyze its transcription in more detail. 5' RACE yielded alternative transcriptional start sites that are predicted to code for N-terminal protein variants. Comparison of the 5' genomic sequence between species identified a transcriptionally active region with three conserved spans. In transgenic mice beta-galactosidase expression driven by this fragment resembled endogenous AE4 expression and was predominantly restricted to type B intercalated cells. Hence this promoter could prove useful to target type B intercalated cells by genetic approaches.",
author = "Moritz Hentschke and Suna Hentschke and Uwe Borgmeyer and Christian H{\"u}bner and Ingo Kurth",
year = "2009",
language = "Deutsch",
journal = "HISTOCHEM CELL BIOL",
issn = "0948-6143",
publisher = "Springer",

}

RIS

TY - JOUR

T1 - The murine AE4 promoter predominantly drives type B intercalated cell specific transcription.

AU - Hentschke, Moritz

AU - Hentschke, Suna

AU - Borgmeyer, Uwe

AU - Hübner, Christian

AU - Kurth, Ingo

PY - 2009

Y1 - 2009

N2 - AE4 is an anion exchanger almost exclusively expressed in the collecting ducts of the kidney. This very restricted expression prompted us to analyze its transcription in more detail. 5' RACE yielded alternative transcriptional start sites that are predicted to code for N-terminal protein variants. Comparison of the 5' genomic sequence between species identified a transcriptionally active region with three conserved spans. In transgenic mice beta-galactosidase expression driven by this fragment resembled endogenous AE4 expression and was predominantly restricted to type B intercalated cells. Hence this promoter could prove useful to target type B intercalated cells by genetic approaches.

AB - AE4 is an anion exchanger almost exclusively expressed in the collecting ducts of the kidney. This very restricted expression prompted us to analyze its transcription in more detail. 5' RACE yielded alternative transcriptional start sites that are predicted to code for N-terminal protein variants. Comparison of the 5' genomic sequence between species identified a transcriptionally active region with three conserved spans. In transgenic mice beta-galactosidase expression driven by this fragment resembled endogenous AE4 expression and was predominantly restricted to type B intercalated cells. Hence this promoter could prove useful to target type B intercalated cells by genetic approaches.

M3 - SCORING: Zeitschriftenaufsatz

JO - HISTOCHEM CELL BIOL

JF - HISTOCHEM CELL BIOL

SN - 0948-6143

ER -