The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research

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The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research. / Schültke, Elisabeth; Fiedler, Stefan; Mewes, Catharina; Gargioni, Elisabetta; Klingenberg, Johannes; Abreu Faria, Guilherme; Lerch, Michael; Petasecca, Marco; Prehn, Franziska; Wegner, Marie; Scholz, Marten; Jaekel, Felix; Hildebrandt, Guido.

In: CANCERS, Vol. 14, No. 20, 5137, 20.10.2022.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

Harvard

Schültke, E, Fiedler, S, Mewes, C, Gargioni, E, Klingenberg, J, Abreu Faria, G, Lerch, M, Petasecca, M, Prehn, F, Wegner, M, Scholz, M, Jaekel, F & Hildebrandt, G 2022, 'The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research', CANCERS, vol. 14, no. 20, 5137. https://doi.org/10.3390/cancers14205137

APA

Schültke, E., Fiedler, S., Mewes, C., Gargioni, E., Klingenberg, J., Abreu Faria, G., Lerch, M., Petasecca, M., Prehn, F., Wegner, M., Scholz, M., Jaekel, F., & Hildebrandt, G. (2022). The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research. CANCERS, 14(20), [5137]. https://doi.org/10.3390/cancers14205137

Vancouver

Bibtex

@article{632d44783011473a9a86d673829f9ca6,
title = "The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research",
abstract = "High dose rate radiotherapies such as FLASH and microbeam radiotherapy (MRT) both have developed to the stage of first veterinary studies within the last decade. With the development of a new research tool for high dose rate radiotherapy at the end station P61A of the synchrotron beamline P61 on the DESY campus in Hamburg, we increased the research capacity in this field to speed up the translation of the radiotherapy techniques which are still experimental, from bench to bedside. At P61, dose rates of several hundred Gy/s can be delivered. Compared to dedicated biomedical beamlines, the beam width available for MRT experiments is a very restrictive factor. We developed two model systems specifically to suit these specific technical parameters and tested them in a first set of experiments.",
author = "Elisabeth Sch{\"u}ltke and Stefan Fiedler and Catharina Mewes and Elisabetta Gargioni and Johannes Klingenberg and {Abreu Faria}, Guilherme and Michael Lerch and Marco Petasecca and Franziska Prehn and Marie Wegner and Marten Scholz and Felix Jaekel and Guido Hildebrandt",
year = "2022",
month = oct,
day = "20",
doi = "10.3390/cancers14205137",
language = "English",
volume = "14",
journal = "CANCERS",
issn = "2072-6694",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "20",

}

RIS

TY - JOUR

T1 - The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research

AU - Schültke, Elisabeth

AU - Fiedler, Stefan

AU - Mewes, Catharina

AU - Gargioni, Elisabetta

AU - Klingenberg, Johannes

AU - Abreu Faria, Guilherme

AU - Lerch, Michael

AU - Petasecca, Marco

AU - Prehn, Franziska

AU - Wegner, Marie

AU - Scholz, Marten

AU - Jaekel, Felix

AU - Hildebrandt, Guido

PY - 2022/10/20

Y1 - 2022/10/20

N2 - High dose rate radiotherapies such as FLASH and microbeam radiotherapy (MRT) both have developed to the stage of first veterinary studies within the last decade. With the development of a new research tool for high dose rate radiotherapy at the end station P61A of the synchrotron beamline P61 on the DESY campus in Hamburg, we increased the research capacity in this field to speed up the translation of the radiotherapy techniques which are still experimental, from bench to bedside. At P61, dose rates of several hundred Gy/s can be delivered. Compared to dedicated biomedical beamlines, the beam width available for MRT experiments is a very restrictive factor. We developed two model systems specifically to suit these specific technical parameters and tested them in a first set of experiments.

AB - High dose rate radiotherapies such as FLASH and microbeam radiotherapy (MRT) both have developed to the stage of first veterinary studies within the last decade. With the development of a new research tool for high dose rate radiotherapy at the end station P61A of the synchrotron beamline P61 on the DESY campus in Hamburg, we increased the research capacity in this field to speed up the translation of the radiotherapy techniques which are still experimental, from bench to bedside. At P61, dose rates of several hundred Gy/s can be delivered. Compared to dedicated biomedical beamlines, the beam width available for MRT experiments is a very restrictive factor. We developed two model systems specifically to suit these specific technical parameters and tested them in a first set of experiments.

U2 - 10.3390/cancers14205137

DO - 10.3390/cancers14205137

M3 - SCORING: Journal article

C2 - 36291920

VL - 14

JO - CANCERS

JF - CANCERS

SN - 2072-6694

IS - 20

M1 - 5137

ER -