The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research
Standard
The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research. / Schültke, Elisabeth; Fiedler, Stefan; Mewes, Catharina; Gargioni, Elisabetta; Klingenberg, Johannes; Abreu Faria, Guilherme; Lerch, Michael; Petasecca, Marco; Prehn, Franziska; Wegner, Marie; Scholz, Marten; Jaekel, Felix; Hildebrandt, Guido.
in: CANCERS, Jahrgang 14, Nr. 20, 5137, 20.10.2022.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - The Microbeam Insert at the White Beam Beamline P61A at the Synchrotron PETRA III/DESY: A New Tool for High Dose Rate Irradiation Research
AU - Schültke, Elisabeth
AU - Fiedler, Stefan
AU - Mewes, Catharina
AU - Gargioni, Elisabetta
AU - Klingenberg, Johannes
AU - Abreu Faria, Guilherme
AU - Lerch, Michael
AU - Petasecca, Marco
AU - Prehn, Franziska
AU - Wegner, Marie
AU - Scholz, Marten
AU - Jaekel, Felix
AU - Hildebrandt, Guido
PY - 2022/10/20
Y1 - 2022/10/20
N2 - High dose rate radiotherapies such as FLASH and microbeam radiotherapy (MRT) both have developed to the stage of first veterinary studies within the last decade. With the development of a new research tool for high dose rate radiotherapy at the end station P61A of the synchrotron beamline P61 on the DESY campus in Hamburg, we increased the research capacity in this field to speed up the translation of the radiotherapy techniques which are still experimental, from bench to bedside. At P61, dose rates of several hundred Gy/s can be delivered. Compared to dedicated biomedical beamlines, the beam width available for MRT experiments is a very restrictive factor. We developed two model systems specifically to suit these specific technical parameters and tested them in a first set of experiments.
AB - High dose rate radiotherapies such as FLASH and microbeam radiotherapy (MRT) both have developed to the stage of first veterinary studies within the last decade. With the development of a new research tool for high dose rate radiotherapy at the end station P61A of the synchrotron beamline P61 on the DESY campus in Hamburg, we increased the research capacity in this field to speed up the translation of the radiotherapy techniques which are still experimental, from bench to bedside. At P61, dose rates of several hundred Gy/s can be delivered. Compared to dedicated biomedical beamlines, the beam width available for MRT experiments is a very restrictive factor. We developed two model systems specifically to suit these specific technical parameters and tested them in a first set of experiments.
U2 - 10.3390/cancers14205137
DO - 10.3390/cancers14205137
M3 - SCORING: Journal article
C2 - 36291920
VL - 14
JO - CANCERS
JF - CANCERS
SN - 2072-6694
IS - 20
M1 - 5137
ER -