The association of the appetitive peptide acetylated ghrelin with alcohol craving in early abstinent alcohol dependent individuals.

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The association of the appetitive peptide acetylated ghrelin with alcohol craving in early abstinent alcohol dependent individuals. / Koopmann, Anne; von der Goltz, Christoph; Grosshans, Martin; Dinter, Christina; Vitale, Meike; Wiedemann, Klaus; Kiefer, Falk.

In: PSYCHONEUROENDOCRINO, Vol. 37, No. 7, 7, 2012, p. 980-986.

Research output: SCORING: Contribution to journalSCORING: Journal articleResearchpeer-review

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Koopmann A, von der Goltz C, Grosshans M, Dinter C, Vitale M, Wiedemann K et al. The association of the appetitive peptide acetylated ghrelin with alcohol craving in early abstinent alcohol dependent individuals. PSYCHONEUROENDOCRINO. 2012;37(7):980-986. 7.

Bibtex

@article{3a34a866434240bbb4c01dd67b0cce0c,
title = "The association of the appetitive peptide acetylated ghrelin with alcohol craving in early abstinent alcohol dependent individuals.",
abstract = "Recent preclinical and clinical studies suggested ghrelin to have an orexigenic role in regulating appetite and energy balance. Preclinical studies also provided support for an important role of ghrelin in the neurobiology of addiction-related reward pathways, affecting the self-administration of alcohol and drugs as well as conditioned place preference. In contrast, clinical data have until now failed to support an association between ghrelin and alcohol craving, possibly due to the fact that these studies have analyzed the pharmacologically inactive, preprohormone ghrelin instead of ghrelin in its active, acetylated form.",
keywords = "Adult, Humans, Male, Middle Aged, Regression Analysis, Psychological Tests, Acetylation, Alcohol Drinking/blood, Alcoholism/*blood/*rehabilitation, Appetite/physiology, Behavior, Addictive/*blood, Ghrelin/*blood/metabolism, Obsessive Behavior/blood, Substance Withdrawal Syndrome/*blood, Adult, Humans, Male, Middle Aged, Regression Analysis, Psychological Tests, Acetylation, Alcohol Drinking/blood, Alcoholism/*blood/*rehabilitation, Appetite/physiology, Behavior, Addictive/*blood, Ghrelin/*blood/metabolism, Obsessive Behavior/blood, Substance Withdrawal Syndrome/*blood",
author = "Anne Koopmann and {von der Goltz}, Christoph and Martin Grosshans and Christina Dinter and Meike Vitale and Klaus Wiedemann and Falk Kiefer",
year = "2012",
language = "English",
volume = "37",
pages = "980--986",
journal = "PSYCHONEUROENDOCRINO",
issn = "0306-4530",
publisher = "Elsevier Limited",
number = "7",

}

RIS

TY - JOUR

T1 - The association of the appetitive peptide acetylated ghrelin with alcohol craving in early abstinent alcohol dependent individuals.

AU - Koopmann, Anne

AU - von der Goltz, Christoph

AU - Grosshans, Martin

AU - Dinter, Christina

AU - Vitale, Meike

AU - Wiedemann, Klaus

AU - Kiefer, Falk

PY - 2012

Y1 - 2012

N2 - Recent preclinical and clinical studies suggested ghrelin to have an orexigenic role in regulating appetite and energy balance. Preclinical studies also provided support for an important role of ghrelin in the neurobiology of addiction-related reward pathways, affecting the self-administration of alcohol and drugs as well as conditioned place preference. In contrast, clinical data have until now failed to support an association between ghrelin and alcohol craving, possibly due to the fact that these studies have analyzed the pharmacologically inactive, preprohormone ghrelin instead of ghrelin in its active, acetylated form.

AB - Recent preclinical and clinical studies suggested ghrelin to have an orexigenic role in regulating appetite and energy balance. Preclinical studies also provided support for an important role of ghrelin in the neurobiology of addiction-related reward pathways, affecting the self-administration of alcohol and drugs as well as conditioned place preference. In contrast, clinical data have until now failed to support an association between ghrelin and alcohol craving, possibly due to the fact that these studies have analyzed the pharmacologically inactive, preprohormone ghrelin instead of ghrelin in its active, acetylated form.

KW - Adult

KW - Humans

KW - Male

KW - Middle Aged

KW - Regression Analysis

KW - Psychological Tests

KW - Acetylation

KW - Alcohol Drinking/blood

KW - Alcoholism/blood/rehabilitation

KW - Appetite/physiology

KW - Behavior, Addictive/blood

KW - Ghrelin/blood/metabolism

KW - Obsessive Behavior/blood

KW - Substance Withdrawal Syndrome/blood

KW - Adult

KW - Humans

KW - Male

KW - Middle Aged

KW - Regression Analysis

KW - Psychological Tests

KW - Acetylation

KW - Alcohol Drinking/blood

KW - Alcoholism/blood/rehabilitation

KW - Appetite/physiology

KW - Behavior, Addictive/blood

KW - Ghrelin/blood/metabolism

KW - Obsessive Behavior/blood

KW - Substance Withdrawal Syndrome/blood

M3 - SCORING: Journal article

VL - 37

SP - 980

EP - 986

JO - PSYCHONEUROENDOCRINO

JF - PSYCHONEUROENDOCRINO

SN - 0306-4530

IS - 7

M1 - 7

ER -